Francisco Nunez

Driven doctoral student focusing on GPCR biology in various mammalian cells to uncover how the cell membrane compartmentalize signal transduction pathways into a localized signal microdomain. Research focuses on how localized signals can impact cellular function, with the goal of fine-tuning signaling responses for potential therapeutic purposes. Utilizing molecular and biochemical approaches as well as novel fluorescent biosensors to examine and characterize the kinetics of cAMP dynamics in response to drugs in live cells. Currently, my project focuses on identifying a Gαs-coupled GPCR that mediates glucocorticoid’s rapid cAMP production that initiates non-genomic signaling in the context of asthma and/or COPD. Working at Lassen Therapeutics will provide me a unique opportunity to uncover novel research approaches and to gain experience with the latest technologies, especially with exciting new research targeting the IL-11 pathway. I believe that with my research experience, especially in the area of fibrosis and pulmonary diseases, I can help advance the company’s goals of developing novel therapeutic strategies for various diseases. Moreover, I seek the grow professionally and build new relationships with team members.