Summary
Overview
Work History
Education
Skills
Accomplishments
Timeline
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Gayan Bamunuarachchi

Summary

Orderly and focused researcher dedicated to innovative, dynamic and organized work. Successful at maintaining accuracy and productivity through long and short-term projects with proven history of efficiency. Extensive knowledge of virology, cellular and molecular biology research and skill in finding additional funding for projects.

Overview

15
15
years of professional experience

Work History

Post-Doctoral Research Associate

Washington University School Of Medicine
01.2021 - Current
  • Therapeutic development for emerging vector borne viruses
  • Development of high throughput drug screens for viral diseases
  • Study the biology of emerging vector borne viruses
  • Serological assay development
  • Vaccine development
  • Maintained accurate records of research findings and provided statistical analysis of data results.
  • Contributed to and actively participated in research conception, design and execution to address defined problems.
  • Communicate research findings using publications, seminars
  • Conduct lab specific training for new trainees
  • SOP and protocol development

Graduate Research Associate

Oklahoma State University, 250 McElroy Hall
07.2014 - 12.2020
  • Identify host factors associated with influenza virus infection
  • Development of therapeutic for respiratory viruses
  • miRNA target screening and validation
  • Prepared summaries of research data for use in high-level meetings and presentations.
  • Used advanced statistical approaches and software tools to analyze data and test hypotheses.
  • Trained undergraduates and monitored progress, answered questions and provided guidance during course of research rotations study.
  • Protocol development

Teaching Assistant

Faculty Of Science, University Of Colombo
07.2013 - 05.2014
  • Lectured and demonstrated physiology, immunology and parasitology lab sessions for all levels of undergraduates on General physiology, Advance immunology and parasitology techniques, Medical parasitology, Biochemistry and molecular biology

Undergraduate Student Researcher

Faculty Of Science, University Of Colombo
01.2009 - 05.2013
  • Interpreted and analyzed research data to draw conclusions on outcomes.
  • Performed routine data analysis to correct and verify data entry.
  • Ordered supplies and equipment to maintain stock and inventory.
  • Maintain animal inventory
  • Statistical analysis (SPSS)

Education

Bachelor of Science - Immunology And Parasitology

Faculty of Science, University Of Colombo
Colombo, Sri Lanka

Ph.D. - Comparative Biomedical Science

Oklahoma State University
Stillwater, OK
12.2020

Skills

  • Serological assay development (FRNT, ELISA)
  • High throughput assay development
  • Drug testing
  • High bio containment level training (BSL2, BSL3 and ABSL3)
  • Reverse genetics and virus rescue
  • Cell culture
  • Virus infection and titration (FFA, plaque assay, TCID50)
  • Animal model development
  • Genotyping and animal colony maintenance
  • Cellular & Molecular biological techniques (PCR, cloning, WB, IF, RNAish)
  • Flow-cytometry
  • Manuscript & grant Writing
  • Findings Presentations
  • Statistical analysis (GraphPad Prism)

Accomplishments

    Publications

    1. Gayan Bamunuarachchi , Xiaoyun Yang, Chaoqun Huang, Yurong Liang, Yujie Guo and Lin Liu, MicroRNA-9-1 Inhibits Influenza A Virus Replication by Targeting Tankyrase 1. Journal of Innate Immunity- accepted (July 2023)

    2. Gayan Bamunuarachchi* , Yujie Guo *, Sunil More, Xiao Xiao, Amber Schofield 2 , Xiaoyun , Yurong Liang, Sanjay Mukherjee, Pradyumna Baviskar, Chaoqun Huang, Shitao, Antonius G. P. Oomens, Jordan Patrick Metcalf and Lin Liu. Axin1: a novel scaffold protein joins the antiviral network of interferon- Molecular Microbiology, 2022

    3. Gayan Bamunuarachchi , Houda Harastani, Paul W. Rothlauf, Ya-nan Dai, Ali, Ellebedy, Daved Fremont, Sean P.J. Whelan, David Wang, Adrianus C. M. Boon. Detection of Bourbon virus specific serum neutralizing antibodies in human serum in Missouri, USA. mSphere, 2022

    4. Gayan Bamunuarachchi, Samuel Jeyasingh, Lin Liu, (review), Interplay between host-non-coding RNAs and influenza viruses, RNA Biology, 2021

    5. Gayan Bamunuarachchi , Xiaoyun Yang, Chaoqun Huang, Yurong Liang, Yujie Guo and Lin Liu, MicroRNA-206 Inhibits Influenza A Virus Replication by Targeting Tankyrase 2- Cellular Microbiology, 2020

    6. Bamunuarachchi GS , Ratnasooriya WD, Premakumara S, Udagama PV. Antimalarial properties of Artemisia vulgaris L ethanolic leaf extract in a Plasmodium berghei murine malaria model. J Vector Borne Dis 2013

    7. Bamunuarachchi GS , Ratnasooriya WD, Premakumara S, Udagama PV. Artemisia vulgaris L. ethanolic leaf extract reverses thrombocytopenia/ thrombocytosis and averts end-stage disease of experimental severe Plasmodium berghei murine malaria. J Vector Borne Dis 2013

    6. Tamarand L. Darling, Baoling Ying, Bradley Whitener, Laura A. VanBlargan, Traci L. Bricker, Chieh-u Liang, Astha Joshi, Gayan Bamunuarachchi , Kuljeet Seehra, Aaron J. Schmitz, Peter J. Halfmann, Yoshihiro Kawoaka, Sayda M. Elbashir, Darin K. Edwards, Larissa B. Thackray, Michael S. Diamond, Adrianus C. M. Boon.mRNA-1273 and Ad26.COV2.S vaccines protect against the B.1.621 variant of SARS-CoV-2. Med. Cell press. 2022.

    7. Lakmini Kumari Senavirathna, Yurong Liang, Chaoqun Huang, Xaioyun Yang, Gayan Bamunuarachchi , Dao Xu, Sivasami Pulavendran, Kishore Vaddadi, Paul Cheresh, David W. Kamp, and Lin Liu. Long noncoding RNA FENDRR inhibits fibroblast proliferation by binding SRSF9 and reducing β-catenin level. International Journal of Molecular Sciences. 2021

    8. Gou, X., Q. Zhang, S. More, G. Bamunuarachchi , Y. Liang, F. Haider Khan, R. Maranville, E. Zuniga, C. Wang and L. Liu (2019). "Repeated Exposure to Streptococcus pneumoniae Exacerbates Chronic Obstructive Pulmonary Disease." Am J Pathol, 2019

    9. Xiaoyun Yang, Chunling Zhao, Gayan Bamunuarachchi , Yang Wang, Zhengyu Zhu, Kong Lin, Lan Xu, Chaoqun Huang, Yurong Liang,Sunile More, Lin Liu. miR-193b represses influenza A virus infection by inhibiting Wnt/β-catenin signaling. Cellular Microbiology. 2019

    10. Sunil More; Xiaoyun Yang; Gayan Bamunuarachchi ; Yujie Guo; Chaoqun Huang; Keith Bailey; Jordan Metcalf; Lin Liu. Regulation of influenza virus replication by Wnt/β-catenin signaling. PLOS ONE. 2018;

    11. Xiaoyun Yang, Yurong Liang, Gayan Bamunuarachchi, Yanzhao Xu, Dao Xu, , Zhengyu Zhu, Rachel Blaha, Chaoqun Huang and Lin Liu, miR-29a is a negative regulator of influenza virus infection through targeting frizzled 5. Archives of Virology, 2020

    12. Qinan Yin, Haodi Ma, Gayan Bamunuarachchi , Xuewei Zheng, Yan Ma. LncRNAs, cell cycle and human breast cancer (review), Human Gene Therapy, 2023

Timeline

Post-Doctoral Research Associate

Washington University School Of Medicine
01.2021 - Current

Graduate Research Associate

Oklahoma State University, 250 McElroy Hall
07.2014 - 12.2020

Teaching Assistant

Faculty Of Science, University Of Colombo
07.2013 - 05.2014

Undergraduate Student Researcher

Faculty Of Science, University Of Colombo
01.2009 - 05.2013

Bachelor of Science - Immunology And Parasitology

Faculty of Science, University Of Colombo

Ph.D. - Comparative Biomedical Science

Oklahoma State University
Gayan Bamunuarachchi