Golam Iftakhar Khandakar

Innovative, hard-working, and result-oriented Postdoctoral research scholar with expertise in cancer cell biology, immunology, and Vascular biology. Strong research experience in cell culture, evaluation of gene expression profiles, protein expression, cell-based assays, and Bioinformatics. Ability to successfully meet scientific challenges and execute diverse scientific projects both individually and in teams. Diligent to deadlines of multiple tasks to ensure completion of project goals. Effective in communication of scientific content to a variety of audiences. Experience in mentoring and leadership skills.

U.S Permanent Resident (No visa sponsorship required)

Completed Clinical Research Training through the Ohio State University Clinical and Translational Science Institute (2026), including coursework in clinical research regulations, clinical trial protocol design and implementation, informed consent, investigational product approval processes, and the role of Institutional Review Boards (IRBs), with emphasis on compliance with U.S. Food and Drug Administration guidelines and ethical standards.

• President’s Research Excellence Accelerator Grant Reviewer, Fall 2025 (Ohio State University)
• Reviewer for Biology Direct, 2023
• Reviewer for Journal of Molecular Histology, 2023-Present
• Reviewer for Scientific Reports, 2024-Present
• Reviewer for Cytotechnology, 2025-Present
• Reviewer for Cancer Gene Therapy, 2025-Present
• Reviewer for European Journal of Medical Research, 2026-Present
• Hayes Forum Abstract Judging, 2026 (Ohio State University)
• Denman Undergraduate Research Forum (Reviewer) , 2026 (Ohio State University)
• Reviewer for BMC Cancer, 2026
• Judge for 2026 State Science Day, The Ohio Academy of Science
• Naunyn-Schmiedeberg's Archives of Pharmacology, 2026

1. Khandakar GI, Satoh R, Takasaki T, et al. ACAGT-007a, an ERK MAPK Signaling Modulator, in Combination with AKT Signaling Inhibition Induces Apoptosis in KRAS Mutant Pancreatic Cancer T3M4 and MIA-Pa-Ca-2 Cells. Cells. 2022;11(4):702. Published 2022 Feb 17. doi:10.3390/cells11040702

2. Khandakar GI, Miyamoto Y, Satoh R, et al. ACAGT-007a, an anti-cancer compound that modulates ERK MAPK signaling, induces nuclear enrichment of phosphorylated ERK in T3M4 pancreatic cancer cells. Genes Cells. 2023;28(6):457-465. doi:10.1111/gtc.13026

3. Takasaki T; Obana R; Fujiwara D; Tomimoto, N; Khandakar, GI; Satoh R; Sugiura, R (2023). ACA-28, an anticancer compound, induces Pap1 nuclear accumulation via ROS-dependent and -independent mechanisms in fission yeast. microPublication Biology. 10.17912/micropub.biology.000711.

4. Takasaki T, Hamabe Y, Touchi K, Khandakar GI, Ueda T, Okada H, Sakai K, Nishio K, Tanabe G, Sugiura R. ACA-28, an ERK MAPK Signaling Modulator, Exerts Anticancer Activity through ROS Induction in Melanoma and Pancreatic Cancer Cells. Oxid Med Cell Longev. 2024 Mar 11;2024:7683793. doi: 10.1155/2024/7683793. PMID: 38500559; PMCID: PMC10948229.

5. Du, W., Ringer, M., Huang, W., Desai, D., Khandakar, G. I., Tron Esqueda, L., Wang, C., Guan, J. L., Becker, R. C., Sadayappan, S., Fan, G. C., Wang, Y., & Fan, Y. (2025). Endothelial Transcription Factor EB Protects Against Doxorubicin-Induced Endothelial Toxicity and Cardiac Dysfunction. Circulation, 10.1161/CIRCULATIONAHA.124.071774. Advance online publication. https://doi.org/10.1161/CIRCULATIONAHA.124.071774

6. Khandakar, G. I., Du, W., Wang, C., Corriere, M., & Fan, Y. (2026). Iron Dysregulation and Vascular Diseases: A Contemporary Review. Journal of the American Heart Association, 15(8), e046547. https://doi.org/10.1161/JAHA.125.046547

7. Du, Wa, Khandakar, Golam Iftakhar, Zhang, Yiting, Wang, Yigang, Fan, Yanbo “Role of Endothelial Reelin in diabetic cardiomyopathy and chronic inflammation”. Circulation Research 2025. doi:10.1161/res.137.suppl_1.Thu112

● Vascular Discovery: From Genes to Medicine

Bellevue, Washington 

May 2026 

Poster Presentation

● The Protein Phosphatase Conference

Palm Springs, CA, USA 

December 2022 

Poster Presentation

● The 44th Annual Meeting of the Molecular Biology Society of Japan (MBSJ)

Pacifico Yokohama, Japan 

December 2021 

Poster Presentation

● 140th Japanese Pharmacological Society Conference 

Nara Prefectural Convention Center, 

Nara, Japan November 2021

Short talk 

● 14th International Conference on Protein Phosphatases

Sysmex Hall and Shinryoku Hall, Kobe University, Graduate School of Medicine, Japan 

December 2020

Short talk and Poster presentation

● International Symposium on Pharmaceutical Science; A Global Approach

University of Science & Technology Chittagong, Bangladesh 

February 2013

Attended

• Research Trainee National Institutes of Biomedical Innovation, Health and Nutrition (NIBIOHN), Ibaraki, Osaka, Japan May 2022–September 2022 Completed a project, “A spatiotemporal analysis of ERK phosphorylation mediated by GT-7” Laboratory of Nuclear Transport Dynamics Project Supervisor: Dr. Masahiro Oka
• Internship Trainee Beximco Pharmaceuticals Ltd, Dhaka, Bangladesh April 2014—May 2014 A 15-day training programme on human resource department, production planning, warehouse, quality control, quality assurance, and development, solid and liquid dosage formulation, infusion unit, engineering services and utilities, environment health & safety and training. Training activities included HPLC, GC, AAS, IR, FTIR, NMR, PH Meter, UV Spectrophotometer, Colorimeter, Liquid and Paper Chromatography, Electronic Balance, and Autoclave.