Grace Guzman
Eau Claire,WI
Summary
Detail-oriented undergraduate student with expertise in cell culture techniques, gene editing, and PCR methods. Strong background in antisense oligonucleotide therapies for rare diseases. Demonstrated ability to analyze data and present findings effectively, contributing to advancements in ALS research.
Overview
3
3
years of professional experience
Work History
Summer Undergraduate Research Fellow
Mayo Clinic
Rochester, Minnesota
05.2026 - 07.2026
- Performed RT-qPCR and ddPCR, analyzed RNA-seq alternative splicing, identified therapeutic targets, and designed splice-switching and Gapmer ASOs to increase TBK1 expression.
- Investigated antisense oligonucleotide (ASO) therapies for TBK1-associated ALS, quantifying TBK1 gene, natural antisense transcripts, and poison exon expression in patient-derived iPSCs and fibroblasts to identify potential therapeutic strategies.
- Analyzed gene-expression changes through statistical evaluation, presenting findings in a scientific research poster to communicate research impact.
Student Peer Mentor
Winnebago Area Literacy Council
Oshkosh, Wisconsin
05.2023 - 08.2023
- Mentored refugee children through individualized support and social activities for integration into American culture.
- Built positive relationships while fostering confidence, communication skills, and personal growth in a supportive environment.
Education
Bachelor of Science - Biochemistry/Molecular Biology
University of Wisconsin, Eau Claire
Eau Claire, WI05-2028
Skills
- Cell culture techniques
- In vitro assays
- Gene editing
- PCR techniques
- Primer & ASO design
- Aseptic technique
- DNA/RNA/Protein purification
- Biosafety protocols
Affiliations
- Founder, Charitable Clothing—Oshkosh, WI (2022-2023)
- Small mammal socialization—Oshkosh, WI (2022-2024)
Timeline
Summer Undergraduate Research Fellow
Mayo Clinic
05.2026 - 07.2026
Student Peer Mentor
Winnebago Area Literacy Council
05.2023 - 08.2023
Bachelor of Science - Biochemistry/Molecular Biology
University of Wisconsin, Eau Claire