HAIYI HUANG

Teaching Classes, Grading Student Assignments, Leading Lab or Discussion Groups in a Course Setting, Proctoring Exams, Holding Office Hours, other duties as assigned.

Principal Investigator： Hua Wang

• Study of Unnatural Sugars Synthesis and immunomaterials

Job Position: Undergraduate Research assistant

- Designed and synthesized novel unnatural sugar molecules, optimizing reactivity and functionality.

- Integrated synthesized unnatural sugars into immunomaterials for targeted immunomodulation studies.

- Conducted extensive in vitro and in vivo experiments to evaluate immunological responses, analyzing complex data.

-Investigated signaling pathways triggered by unnatural sugars, elucidating underlying mechanisms.

• UV responsible of metabolic

Job Position: Main Researcher

-Synthesizing the compound using chemistry synthesis techniques.

-Conducting cell culture using 4T1 cancer cells. In this step, the synthesized compound is added to the cells under UV light.

-The compound will release the azido group, which will then label the cell surface for further drug applications.

• Synthesize immune cell homing bioadhesive macroporous hydrogel by cryo-polymerization.

Job Position: Undergraduate Research assistant

-UV initiated free radical polymerization of double crosslinking polymer network with gelatin and poly acrylic acid.

-Used FACS analysis to analyze immune cell profile of recruited cells in the biomaterials after the subcutaneous implantation.

-Analyzed the activation of dendritic cells after in vitro treatment of tumor exosome by FACS analysis with different activation markers (i.e. CD86, MHCII, CD40, and CCR)