Michael Hanna, PhD
Postdoctoral Research Scientist
Summary
Spirited and innovative scientist capable of providing powerful solutions to complex biological and biochemical problems. I am currently seeking a position where my creative skillset will be more appropriately utilized to advance the horizons of biotechnology for the betterment of societal health from on a global scale. I take pride in my ability to efficiently acquire new skills and I am confident in my ability to rationally interpret new knowledge or information that is presented.
Overview
10
10
years of professional experience
Work History
Postdoctoral Research Scientist
University Of Florida, Chemical Engineering
08.2023 - Current
- Current work is focused on advancing the horizon of gene therapy and diagnostic tools using the latest in CRISPR/Cas technology.
- Tasked with handling several different projects, both independently and as a member of a team, to discover, design, and develop new RNA-guided endonuclease systems that are better capable of performing desired genetic modifications and improving current detection methods for impactful diseases.
- Primary project is the rapid identification of bladder cancer from patient urine samples by detection of specific mRNA biomarker fingerprints without the need for RNA-signal amplification.
Graduate Student (Ph. D. Candidate)
University Of Florida, Department Of Chemistry
08.2017 - 08.2023
- PhD dissertation research focused on the discovery and development of novel chemotherapeutic drugs by combining computational and in vitro lab techniques, connecting mechanistic enzymology with structural biology.
- Significantly advanced understanding of allosteric regulatory mechanisms in enzymes while directing the design and discovery of small-molecule drug targets with increased specificity and affinity for the ubiquitous, essential enzyme ribonucleotide reductase.
Undergraduate Research Assistant
University Of Florida, Department Of Chemistry
08.2014 - 01.2017
- Combined classic biochemical methodology with contemporary techniques to engineer enzymatic systems to produce novel bio-organic compounds.
Bartender
Oozoo, Gainesville
11.2016 - 04.2017
- Connected daily with customers and vendors to encourage and enhance present situations while promoting a welcoming and comfortable environment in an effort to sustain business and life satisfaction
- Served high customer volumes during special events, nights, and weekends.
- Handled simultaneous customer, team, and business needs while avoiding unnecessary delays or errors.
Lead Barback / Pizza Chef
Oozoo & Dough Religion
08.2016 - 04.2017
- Operated pizza oven and other kitchen equipment safely to provide quality meals to customers while protecting team members from harm and equipment from damage.
- Recruited and trained new barbacks and kitchen staff to help maintain talented team.
Education
Ph.D. - Chemistry | Chemical Biology
University of Florida
Gainesville, FL 08.2017 - 2023.08
Bachelor of Science - Biochemistry
University of Florida
Gainesville, FL 01.2012 - 2016.05
High School Diploma -
Lake Howell High School
Winter Park, FL 03.2010 - 2011.05
Skills
Research
Accomplishments
- Four-time USA Wakeboard Collegiate National Champion (Gator Wake 2014-2017)
- Graduate Teaching Award (UF 2020)
- Eagle Scout (2011)
Publications
Michael P. Hanna , Kandice Simmons, Swapnil Joshi, Maria del Pilar Buteler, Adrian E. Roitberg* & Michael E. Harris*, Advanced Understanding of Ribonucleotide Reductase Allosteric Regulatory Mechanisms Reveal New Avenues for Small-Molecule Inhibition. (2024, in prep)
Maria del Pilar Buteler, Michael P. Hanna , Kandice Simmons, Swapnil Joshi, Maria del Pilar Buteler, Adrian E. Roitberg* & Michael E. Harris*, ATP and dATP Driven Activation and Inhibition of Ribonucleotide Reductase. (2024, in prep)
Michael Hanna , The Deoxy Code: Uncovering The Mechanisms That Control Human Ribonucleotide Reductase Allosteric Regulation. Dissertation - University of Florida, Department of Chemistry, 2023
Beaudoin SF, Hanna MP , Ghiviriga I, Stewart JD. Progress in using threonine aldolases for preparative synthesis. Enzyme Microb Technol. 2018 Dec;119:1-9. doi: 10.1016/j.enzmictec.2018.07.004. Epub 2018 Jul 30. PMID: 30243380.
Leadership Positions
- Captain of Gator Wake (UF National Champion Wakeboard Team) (2014-2017) - Vice President (2015-2016)
- Captain of Hume-Fogg Academy Ice Hockey Team (2008-2010) - Assistant Captain (2007-2008)
- Captain and co-founder of Hume-Fogg Academy Lacrosse Team (2007-2010)
- Boy Scout Troop 217 Assistant Senior Patrol Leader (2009-2010)
- Order of the Arrow Representative (2007-2010)
- Patrol Leader (2005-2007)
- Captain of Meigs Magnet School Wrestling Team (2005-2007)
- Captain of Meigs Magnet School Soccer Team (2006-2007)
- Captain of Meigs Magnet School Chess Team (2004-2006)
Timeline
Postdoctoral Research Scientist
University Of Florida, Chemical Engineering
08.2023 - Current
Graduate Student (Ph. D. Candidate)
University Of Florida, Department Of Chemistry
08.2017 - 08.2023
Ph.D. - Chemistry | Chemical Biology
University of Florida
08.2017 - 2023.08
Bartender
Oozoo, Gainesville
11.2016 - 04.2017
Lead Barback / Pizza Chef
Oozoo & Dough Religion
08.2016 - 04.2017
Undergraduate Research Assistant
University Of Florida, Department Of Chemistry
08.2014 - 01.2017
Bachelor of Science - Biochemistry
University of Florida
01.2012 - 2016.05
High School Diploma -
Lake Howell High School
03.2010 - 2011.05
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