JACQUELINE DUNN
Ansonia,CT
Summary
Experienced Senior Associate Scientist with a strong background in laboratory operations. Proficient in cell culture, in-vivo and in-vitro assays, and assay development. Proven ability to design and execute experiments, analyze data, and contribute to scientific research projects. Committed to maintaining high quality standards and accurate documentation.
Overview
7
7
years of professional experience
Work History
Senior Associate Scientist
ARVINAS
12.2022 - Current
- Support internal targets with in-vivo and in-vitro assays, and assay development.
- Characterize drug compounds in multiple cancer cell lines through in-vitro and in-vivo assays.
- Process large scale in-vivo experiments by traditional western blotting and automated western blotting (Jes and Abby).
- Develop and optimize target engagement assays such as NanoBRET.
- Characterize cytotoxicity of lead compounds and PROTACs in disease-relevant cell lines by Cell-Titer Glo assays.
- Validate targets in relevant cell lines using genetic tools such as siRNA.
- Develop dTAG cell lines and single-cell clones.
Associate Scientist
ARVINAS
10.2021 - 12.2022
- Support external collaboration with in-vitro assays, data analysis and in-vivo studies.
- Characterize PROTACs by in-vitro assays including In-cell Westerns, Western blotting and Cell-Titer Glo.
- Select PROTACs based on generated data to move forward in-vivo.
- Maintain six cell lines including AML12, RAW 264.7, HEK293, A549, C166, and 3T3-L1 cells.
- Document and analyze data with Sciligence, ACAS, Prism and Image Lab. Present data to support external target.
- Support assay development.
Senior Research Associate
ABCAM
04.2021 - 10.2021
- Promoted to Senior Research Associate
Research Associate
ABCAM
01.2021 - 04.2021
- Developed novel antibodies through RabMab discovery pipeline.
- Used liquid handling automation to support high throughput assay screening.
- Screened serums and antibodies with assays such as ELISA, and Western and Surf blots.
- Created hybridomas with PEG fusion.
- Supported data management through recording and analyzing data with laboratory notebooks.
- Communicated results to supervisors and peers.
Histo-technician
LABCORP
09.2018 - 01.2021
- Promoted to histo-technician from a tech-trainee position in five months due to quick learning and work ethic. ASCP eligible.
- Operate and maintain equipment used for embedding and sectioning specimens.
- Follow safety requirements and appropriately handle and dispose of chemicals.
- Prepare tissue specimens for routine and special procedures.
Graduate Assistant
SOUTHERN CONNECTICUT STATE UNIVERSITY
01.2020 - 05.2020
- Selected for a graduate assistantship role by the department chair of biology.
- Setup classroom labs for professors and assemble new classrooms.
- Inventory and order stock for undergraduate classes.
Education
Bachelor's of Science -
SOUTHERN CONNECTICUT STATE UNIVERSITY
05.2018
Skills
- Western blotting proficiency
- Critical thinking and problem solving
- Cell line development
- Assay validation experience
Timeline
Senior Associate Scientist
ARVINAS
12.2022 - Current
Associate Scientist
ARVINAS
10.2021 - 12.2022
Senior Research Associate
ABCAM
04.2021 - 10.2021
Research Associate
ABCAM
01.2021 - 04.2021
Graduate Assistant
SOUTHERN CONNECTICUT STATE UNIVERSITY
01.2020 - 05.2020
Histo-technician
LABCORP
09.2018 - 01.2021
Bachelor's of Science -
SOUTHERN CONNECTICUT STATE UNIVERSITY
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