Summary
Overview
Work History
Education
Skills
Certification
Publications
Presentations
Timeline
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Jam Prakash

Indianapolis,USA

Summary

Results-driven research professional with over ten years of experience in Pathology and Biochemistry, specializing in managing multiple studies and ensuring compliance with protocols. Demonstrated expertise in data collection, analysis, and reporting, consistently upholding high ethical standards while delivering accurate research outcomes. Highly skilled in statistical analysis and data visualization, with a proven track record of identifying patterns and effectively communicating findings. Known for a collaborative approach that aligns team objectives with organizational goals.

Overview

28
28
years of professional experience
1
1
Certification

Work History

Research Analyst

Indiana University, School of Medicine
Indianapolis, USA
03.2023 - Current
  • Optimized protocols for antibody validation for use in clinical IHC diagnostic tests
  • Conducted in-depth qualitative and quantitative assessment for research studies to identify best targets for xenograft and biopsy experiments
  • Collaborated with cross-functional teams to generate viable testing strategies for cancer diagnostics

Histotechnologist

AmeriPath-Indiana, Quest Diagnostics
Indianapolis, USA
05.2022 - 02.2023
  • Actively engaged in troubleshooting complex cases independently.
  • Improved turnaround time by implementing updated staining procedures and techniques.
  • Handled sensitive patient data with strict confidentiality, ensuring compliance with data protection regulations.

Histotechnologist

University of Pennsylvania, School of Medicine
Philadelphia, USA
10.2016 - 01.2018
  • Prepared tissue samples for preclinical studies under GLP conditions.
  • Performed histological consults for human tissue and body fluid specimens to prepare for clinical trials.
  • Conducted a microscopic analysis, generating supporting data for clinical target exploration.
  • Collaborated with internal departments such as Regulatory Affairs and Data Management to ensure that all studies were conducted in accordance with ICH-GCP guidelines.

Graduate Student Research Assistant - Pharmacology

Drexel University, College of Medicine
Philadelphia, USA
08.2014 - 09.2016
  • Project: To determine the role and function of chloride intracellular ion channels (CLICs) in platelet activation, shape change, and aggregation.
  • Established fractionation method for platelets to determine CLIC localization.
  • Organized materials for poster presentations at professional conferences.
  • Collaborated with other graduate student researchers on joint projects.

Graduate Research Assistant - Medical Science

Drexel University, College of Medicine
Philadelphia, USA
08.2012 - 07.2014
  • Project: To determine the role of estrogen and matrix metalloproteinase 2 (MMP2) in platelet activation, shape change, and aggregation.
  • Optimized confocal microscopy protocol for observing MMP2-platelet protein complexes in platelets.
  • Participated in manuscript preparation, leading to the publication of clinically significant articles.

Research Assistant II

Tufts University, Molecular Cardiology Research Institute
Boston, USA
12.2007 - 08.2010
  • Project: To determine the role of the bone morphogenetic protein (BMP) signaling pathway in the inflammatory response of pulmonary artery smooth muscle (PASM) and pulmonary artery endothelial (PAEC) cells during tissue damage.
  • Assisted in the design and implementation of experimental protocols.
  • Managed multiple research projects simultaneously while ensuring accurate record keeping.
  • Presented findings at professional conferences or seminars as required by faculty supervisors.

Research Assistant II - Pathology

Brown University, School of Medicine
Providence, USA
08.2000 - 02.2003
  • Project: To determine which complexes are involved in platelet clotting for possible stroke prevention targets.
  • Provided support for faculty members with grant applications related to research projects.
  • Conducted primary and secondary research to identify relevant information for project development.
  • Prepared informed consent forms for review by ethics committees.
  • Assisted in writing RO1 grant proposals for additional funding opportunities for ongoing projects.

Research Assistant I - Immunology

Brown University, School of Medicine
Providence, USA
08.1999 - 07.2000
  • Project: To find a viable drug target for the parasite T. brucei, the causative agent of African sleeping sickness.
  • Executed preparation of BSL2 samples employing multiple molecular and cell biology strategies.
  • Verified accuracy of data by conducting quality assurance checks on collected materials.

Research Assistant I - Pathology

Brown University, School of Medicine
Providence, USA
10.1997 - 07.1999
  • Project: To determine which proteins regulate platelet clotting.
  • Collaborated with other researchers in developing study designs, methods, and tools for data collection.
  • Drafted manuscripts for submission to peer-reviewed journals.
  • Assisted in the preparation of Institutional Review Board documentation for RO1 grant submissions.

Education

Master of Science - Medical Sciences - Incomplete

University of Queensland
Queensland, Australia
01-2020

Master of Science - Histotechnology

Drexel University
Philadelphia, PA
05.2015

Master of Science - Interdisciplinary Health Sciences

Drexel University
Philadelphia, PA
05.2013

Bachelor of Arts - Biology

Boston University
Boston, MA
01.1997

Bachelor of Arts - Archaeological Studies

Boston University
Boston, MA
01.1997

Skills

  • Team collaboration
  • Statistical analysis
  • Protocol optimization
  • Protocol development
  • Data collection and analysis
  • Interpersonal skills
  • Disease research
  • Analytical mindset
  • Cross-functional collaboration
  • Regulatory compliance
  • Research methodology
  • Documentation skills
  • Good clinical practices
  • Research design

Certification

ASCP - HTL certification, #8155

Publications

  • Ruizhong Wang, Adedeji K. Adebayo, Steven Westphal, Hala Fatima, Carla Fisher, Hongyu Gao, Yunlong Liu, Ryla Grace House, George Sandusky, Jamunabai M Prakash, Amber Roberts, Matt Thomas, Mohammad Al-Haddad, Sujani Yadlapati, Pam Rockey, William A. C. Berry, Mary Beth James, Rana German, Emily Nelson, April Giron, Kathy D. Miller, Harikrishna Nakshatri, The Impact of Oxygen Exposure on Clinical Biomarkers an underrecognized source of pre-analytic variability, Abstract
  • Guohua Liang, Jamunabai M. Prakash, Dongwei Zhang, Iván A. González, The Role of Adenovirus Immunohistochemistry in Acute Appendicitis in Children, Abstract
  • Yukiko Kitagawa, Mehdi Nassiri, Hector Mesa, Jamunabai Prakash, Nikolay Popnikolov, Possible role of anastrozole-induced hormonal alterations in pathogenesis of mammary apocrine carcinoma and follicular lymphoma: a case report and literature analysis, Journal of Medical Case Reports, 2024
  • Soslau G, Mason C, Lynch S, Benjamin J, Ashak D, Prakash JM, Moore A, Bagsiyao P, Albert T, Mathew LM, Jost M, Intracellular matrix metalloproteinase-2 (MMP-2) regulates human platelet activation via hydrolysis of talin, Thrombosis and Haemostasis, 2014, 111, 1, 140-53, 10.1160/TH13-03-0248, 2013-10-17
  • Patel NH, Mitteer, R. Alan, Prakash JM, Borodevyc, OV, Soslau, G, New Clues To The Mechanism of Cardioprotection by Estrogen, Abstract, Blood, 2013, 122, 21, 4736, 10.1160/TH13-03-0248, 2013-10-17
  • Wang D, Prakash JM, Nguyen, P, Davis B, Hill N, Layne, MD, Hata A, Lagna G, Bone morphogenetic protein signaling in vascular disease: anti-inflammatory action through myocardin-related transcription factor A, Journal of Biological Chemistry, 2012, 287, 33, 28067-77, 10.1074/jbc.M112.379487, 2012-06-20
  • Bearer EL, Prakash JM, Li Z, Actin Dynamics in Platelets, International Review of Cytology, 2002, 217, 137-82
  • Bearer EL, Prakash JM, Manchester RD, Allen PG, VASP Protects Actin Filaments From Gelsolin: An In Vitro Study With Implications for Platelet Actin Reorganizations, Cell Motility and the Cytoskeleton, 2000, 47, 351-64

Presentations

  • Localization and Function of CLICs in Human Platelet Aggregation, Jamunabai M Prakash, Nishi H Patel, Ahmed T Hussain, Devasena Ponnalagu, Harpreet Singh, Drexel Discovery Day, 2016, Poster presentation, Philadelphia, PA, USA
  • Localization and Role of CLICs in Human Platelet Aggregation, Jamunabai M Prakash, Nishi H Patel, Ahmed T Hussain, Devasena Ponnalagu, Harpreet Singh, Drexel Discovery Day, 2015, Poster presentation, Philadelphia, PA, USA
  • Human Platelet Estrogen Receptors: Localization and their Role in Aggregation, Nishi H Patel, Richard A Mitteer, Jamunabai M. Prakash, Oresta Borodevyc, Gerald Soslau, Harpreet Singh, American Society for Cell Biology Meeting, 2014, Poster presentation, Philadelphia, PA, USA
  • Human Platelet Estrogen Receptors: Localization and their Role in Aggregation, Nishi H Patel, Richard A Mitteer, Jamunabai M. Prakash, Oresta Borodevyc, Gerald Soslau, Drexel Discovery Day, 2014, Poster presentation, Philadelphia, PA, USA
  • New Clues to the Mechanism of Cardioprotection by Estrogen, Nishi H Patel, Richard A Mitteer, Jamunabai M. Prakash, Oresta Borodevyc, Gerald Soslau, Drexel Discovery Day, 2013, Poster presentation, Philadelphia, PA, USA
  • BMP signaling in Vascular homeostasis: Anti-inflammatory action through Inhibition of NF-κB signaling, Dahai Wang, Jamunabai M. Prakash, Peter Nguyen, Akiko Hata, Giorgio Lagna, 8th International Conference on Bone Morphogenetic Proteins, 2010, Poster presentation, Leuven, Belgium
  • BMP signaling in Vascular homeostasis: Anti-inflammatory action through Inhibition of NF-κB signaling, Dahai Wang, Jamunabai M. Prakash, Brandi Davis, Richard Warburton, Nicholas Hill, Akiko Hata, Giorgio Lagna, MCRI Annual Retreat, 2010, Poster presentation, Woods Hole, MA, USA
  • BMP signaling potently inhibits inflammation in both Pulmonary Artery Smooth Muscle and Endothelial Cells, Jamunabai M. Prakash, Dahai Wang, Akiko Hata, Giorgio Lagna, MCRI Annual Retreat, 2009, Poster presentation, Woods Hole, MA, USA
  • The Role of BMP Signaling in Vascular Calcification, Jamunabai M. Prakash, Maria Nurminskaya, Akiko Hata, Giorgio Lagna, MCRI Annual Retreat, 2008, Poster presentation, Woods Hole, MA, USA
  • Regulation of Arp2/3, Actin Polymerization, and the Role of Small G-Proteins in Human Blood Platelets, Jamunabai M. Prakash, Eric S. Kim, Elaine L. Bearer, American Society for Cell Biology Meeting, 2002, Poster presentation, San Francisco, USA
  • The Arp2/3 complex is Required for Platelet Shape Change, Elaine L. Bearer, Jamunabai M. Prakash, Eric S. Kim, Zhi Li, American Society for Cell Biology, 2001, Poster presentation, Washington D.C., USA
  • Effects of Platelet Gelsolin and VASP on Actin Filament Dynamics, Jamunabai M. Prakash, Robert D. Manchester, Elaine L. Bearer, American Society for Cell Biology, 1998, Poster presentation, San Francisco, USA

Timeline

Research Analyst

Indiana University, School of Medicine
03.2023 - Current

Histotechnologist

AmeriPath-Indiana, Quest Diagnostics
05.2022 - 02.2023

Histotechnologist

University of Pennsylvania, School of Medicine
10.2016 - 01.2018

Graduate Student Research Assistant - Pharmacology

Drexel University, College of Medicine
08.2014 - 09.2016

Graduate Research Assistant - Medical Science

Drexel University, College of Medicine
08.2012 - 07.2014

Research Assistant II

Tufts University, Molecular Cardiology Research Institute
12.2007 - 08.2010

Research Assistant II - Pathology

Brown University, School of Medicine
08.2000 - 02.2003

Research Assistant I - Immunology

Brown University, School of Medicine
08.1999 - 07.2000

Research Assistant I - Pathology

Brown University, School of Medicine
10.1997 - 07.1999

Master of Science - Medical Sciences - Incomplete

University of Queensland

Master of Science - Histotechnology

Drexel University

Master of Science - Interdisciplinary Health Sciences

Drexel University

Bachelor of Arts - Biology

Boston University

Bachelor of Arts - Archaeological Studies

Boston University
Jam Prakash