Hi, I’m
Joanna Winstone
PhD Candidate
Phoenix,AZ.
Summary
Self-driven PhD candidate currently preparing to defend her dissertation June 2023. Exceptionally organized and productive scientist with over seven years of laboratory experience performing high level neuroscience, molecular/cellular biology, genetics, and genomics. Strong communicator with expertise in written publication and oral dissemination of research findings to broad audiences. Seeking a position that offers professional and scientific challenges utilizing interpersonal skills, excellent time management and problem-solving skills.
Overview
7
years of professional experience
7
years of post-secondary education
Work History
The Biodesign Institute, Tempe, AZ
Graduate Research Assistant
08.2019 - Current
Job overview
- Conceptualized and conducted impactful preventative and therapeutic preclinical research in the Alzheimer’s disease field
- Investigated the role of environmental toxins in the progression of neurodegenerative diseases
- Developed and implemented computational pipelines to maximize data analytics in genomics and large volume animal behavior data
- Co-wrote and obtained a $100,000 grant from the Edson Initiative for Dementia Care and Solutions
- Co-authored two manuscripts in high impact journals
- Primary author on one high impact publication with two additional first-author publications in preparation
- Collaborated with others in team-based environment to conduct multidisciplinary studies
- Performed statistical, qualitative, and quantitative analysis.
Indiana University, IN
Undergraduate Research Assistant
01.2016 - 06.2019
Job overview
- Examined a link between adolescent exposure to endo- and phytocannabinoids and increased risk of adult-onset schizophrenia
- Designed a CRISPR/Cas9 system for genetic knockdown of a gene commonly associated with endocannabinoid signaling
- Integrated RNAseq data, Ingenuity Pathway Analysis, RTqPCR, and Western Blot analyses to assess brain function following adolescent cannabinoid exposure
Education
Arizona State University , Tempe, AZ
Ph.D. from Neuroscience
08.2019 - Current
University Overview
- 4.0 GPA
- Recipient of the Service Award from the Graduate and Professional Student Association (2023)
- Recipient of the Research Excellence Award from the Graduate and Professional Student Association (2022)
- Recipient of the Crisis Innovation Award from the Graduate and Professional Student Association (2020)
- Recipient of 8 separate travel awards
- Named a School of Life Sciences Student Leader
- Leader of both the Biodesign Student Association and the School of Life Sciences Graduate Executive Board
- PHX Walk to End ALZ Team Captain
- Relevant Coursework: Molecular Genetics & Genomics, Functional Genomics, Computing for Research, Advanced Statistics
Indiana University , Bloomington, IN
Bachelor of Science from Neuroscience
08.2015 - 05.2019
University Overview
- Ranked in top 1% of class
- Graduated with High Distinction
- Recipient of numerous Hutton Honors College research awards
- Involved in many philanthropic organizations
Skills
Experimental designundefined
Accomplishments
As a Graduate Student:
Dave, N., Judd, J.M., Decker, A., Winslow, W., Sarette, P., Villarreal Espinosa, O., Tallino, S., Bartholomew, S.K., Bilal, A., Sandler, J., McDonough, I., Winstone, J. K., Blackwood, E.A., Glembotski, C., Karr, T., Velazquez, R. Dietary choline intake is necessary to prevent systems-wide organ pathology and reduce Alzheimer's disease hallmarks. Aging Cell. (2023) Jan 15:e13775. https://doi.org/10.1111/acel.13775.
Winstone, J. K., Pathak, K., Winslow, W., Piras, I., White, J., Sharma, R., Huentelman, M. J., Pirrotte, P., Velazquez, R. Glyphosate infiltrates the brain and increases pro-inflammatory cytokine TNFα: implications for neurodegenerative disorders. J Neuroinflammation 19, 193 (2022). https://doi.org/10.1186/s12974-022-02544-5
Dave, N., Vural, A., Stefano Piras, I., Surendra, L., Winstone, J. K., Winslow, W., Huentelman, M., and Velazquez, R. Identification of retinoblastoma binding protein 7 (Rbbp7) as a mediator against tau acetylation and subsequent neuronal loss in Alzheimer’s disease and related tauopathies. Acta Neuropathologica 142, 279–294 (2021). https://doi.org/10.1007/s00401-021-02323-1
As an Undergraduate Student:
Winstone, J., Shafique, H., Clemmer, H. E., Mackie, K., Wager-Miller, J. Effects of Tetrahydrocannabinol and Cannabidiol on Brain-Derived Neurotrophic Factor and Tropomyosin Receptor Kinase B Expression in the Adolescent Hippocampus. Cannabis and Cannabinoid Research. (2022). https://doi.org/10.1089/can.2021.0025
Murphy, M., Mills, S., Winstone, J., Leishman, E., Wager-Miller, J., Bradshaw, H., & Mackie, K. Chronic Adolescent Δ9-Tetrahydrocannabinol Treatment of Male Mice Leads to Long-Term Cognitive and Behavioral Dysfunction, Which Are Prevented by Concurrent Cannabidiol Treatment. Cannabis and Cannabinoid Research, 2(1), 235–246 (2017). http://doi.org/10.1089/can.2017.0034
Press Releases
- 2022 AZ PBS Interview with Drs. Velazquez and Pirrotte: TV coverage of my most recent first author paper
- 2022 AZ Central Article: Press Interview with myself and Dr. Velazquez about my most recent first author paper
- 2022 The New Lede: Press interview with Dr. Velazquez about my most recent first author paper
- 2022 ASU News Article: Press Interview with myself and Dr. Velazquez about my most recent first author paper
- 2020 ASU News Article: Coverage of the grant Dr. Velazquez and I wrote to fund my recently published work
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