KARAN PRAJAPATI
Piscataway,NJ
Summary
Pursued Master of Science in Biotechnology, University of South Florida. Experienced in pharmaceutical and development of drug formulations including nano formulation, dermatological formulation, analgesic formulations, ophthalmic formulations etc. Determined and well-rounded individual with more than 1 and half years working as Scientist within Amneal Pharmaceuticals industry. Sharp and focused professional offering skills in Drug Development and Formulaton . Communicative Scientist proficient in Formulation . Talented individual educated in safety procedures, processes and regulations. Pursuing role and leveraging exceptional technical knowledge to better satisfy customer needs.
Overview
22
22
years of professional experience
Work History
SCIENTIST II
AMNEAL PHARMACEUTICALS LLC.
03.2022 - Current
- Performed and executed formulation development projects including, suspension, ophthalmic emulsion, and topical ointment, injection etc
- Performed and executed ANDA (Abbreviated new drug application) batches including the cGMP (Good manufacturing practices) and scale up batches of 500L and 200L batch size using the 500L and 200 L jacketed tank and propeller mixer
- Hands on experience in document preparation for ANDA batches for example MBR (Master Batch record) and PBR (Packaging Batch record) and Planned deviation
- Performed and executed packaging procedure for the ANDA batches using the IPS filler (Integrated packaging system And Semi-Automatic filler for bottles Under supervision)
- Performed and executed the Dosage cup filling using Inline cup filling machine and sealing
- Hands on experience in making Lab scale R&D batches using IKA mixers and IKA LR 1000 mixer (Closed chamber) with IKA RC 2 (for cooling) and Silverson Homogenizer (high shear lab mixer) and maintaining the stability schedule
- Hands on experience in making a scale up batch of Ointment using Becomix machine operate on PROMAS CS software and after that filling the tubes using REB Air operated Tabletop single
- Documented changes during experiments, noting unexpected issues arising during research activities.
- Conducted experiments in laboratory environment for product development purposes.
- Performed complex troubleshooting and assisted in leading initiatives to solve challenging scientific problems with assays or instrumentation.
- Trained new employees on areas of technical expertise and compliance issues relevant to lab setting.
- Read literature related to scientific area of expertise to remain current in knowledge.
- Self-motivated, with a strong sense of personal responsibility.
- Worked effectively in fast-paced environments.
- Worked well in a team setting, providing support and guidance.
RESEARCH ASSOCIATE
SGN NANOPHARMA INC
12.2020 - 01.2022
- Performed and executed formulation development projects including analgesic, ophthalmic and topical nanoformulation
- Performed the pre-clinical procedures for the penetration and retention studies of the developed formulation using the human skin and corneal tissue binding studies using Franz Diffusion cell system
- Performed the various characterization using the Malvern zetasizer, viscometer, Lumisizer, and osmometer to analyze the particle size, zeta potential, phase separation, viscosity and osmolality
- Hands on experience in handling the Chromatographic techniques using HPLC (High pressure liquid chromatography and UPLC (Ultra pressure liquid chromatography
- Hands on experience in method development and validation using the HPLC and UPLC instruments
- Experienced with LCMS under supervision of the Lab Research scientist
- Hands on experience in Interpretation of Purity plot and chromatograph
- Internship project: Method development and validation of Cyclosporine Drug using the UPLC method
- O
- Piston Filler with Hopper
- Hands on experience in Handling the GRISO TUB MS (double fold Crimper) for crimping the tubes
- Hands on experience in using Brookfield viscometer for measuring Viscosity
- Hands on Experience in carrying out the Particle size of the API using The Microscopy
- Hands on experience in Handling the Control substance under DEA (Drug enforcement administration) regulations
- Performed and executed the operation on Dyno mill for dispersion and wet grinding in the suspension.
- Gathered, arranged, and corrected research data to create representative graphs and charts highlighting results for presentations.
- Helped team meet regulatory requirements by coordinating documentation and filings.
STUDENT VOLUNTEER
University Of South Florida College Of Medicine
02.2002 - 04.2020
- Assisted in analytical techniques such as HPLC, UV-Vis spectroscopy
- Assisted in maintaining ARPE-19 cell line
- Took and followed detailed directions from others.
- Worked in team environment to maintain high levels of productivity.
- Assisted preparation and characterization of nanoparticles
OPERATION MANAGER
M/S KAPSAN PHARMATECH
10.2018 - 04.2019
- Acquainted with pharmaceutical machinery and services division
- Lead the team of 5 people for the operations carried out in the company
- Hands-on experience in fixing various parts of the pharmaceutical machinery.
UDENT INTERN, AGOG PHARMA LTD
07.2018 - 08.2018
- Successfully completed practical training in production, Quality Assurance and Quality Control
- Department.
RESEARCH INTERN
DAIWIK PHARMASPHERE PVT. LTD
05.2018 - 06.2018
- Successfully completed practical training in the Research and development department and production and packing department.
Education
BACHELOR'S - PHARMACY
GUJARAT TECHNOLOGICAL UNIVERSITY
Master of Science - BIOTECHNOLOGY
UNIVERSITY OF SOUTH FLORIDA
Tampa, FL12.2021
Skills
- Computational:
- Microsoft suite
- Minor Repairs
- Project Requirements
- Critical Thinking
- DNA Sequencing
Accomplishments
- CGMP
- REB Air operated Tabletop single piston Filler with Hopper
- Bioanalytical: HPLC(Empower), UHPLC, LCMS
- Handling Formulation including API such as cannabinoids
- Skin penetration study
- Laboratory experience (wet lab)
- Zetasizer, Lumisizer, Brookfield viscometer
- Franz Diffusion cell
- Handling the controlled substances
- Documentation
- Interaction and calculation
- Purity plot
Additional Information
- PCR (polymerase chain reaction) and electrophoretic techniques. Gene editing technique using Snap gene software and Pymol. e Media preparation and sterilization. Inoculation and culture preparation of micro-organisms via streak plate method Nanoscale drug delivery.
Languages
English
Professional Working
Hindi
Native or Bilingual
Timeline
SCIENTIST II
AMNEAL PHARMACEUTICALS LLC.
03.2022 - Current
RESEARCH ASSOCIATE
SGN NANOPHARMA INC
12.2020 - 01.2022
OPERATION MANAGER
M/S KAPSAN PHARMATECH
10.2018 - 04.2019
UDENT INTERN, AGOG PHARMA LTD
07.2018 - 08.2018
RESEARCH INTERN
DAIWIK PHARMASPHERE PVT. LTD
05.2018 - 06.2018
STUDENT VOLUNTEER
University Of South Florida College Of Medicine
02.2002 - 04.2020
BACHELOR'S - PHARMACY
GUJARAT TECHNOLOGICAL UNIVERSITY
Master of Science - BIOTECHNOLOGY
UNIVERSITY OF SOUTH FLORIDA
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