Kavitha Priya Kettimuthu Ph.D

Developed and validated robust MRM-based methods using AGILENT: LC-MS/MS 6495 using HILIC – Z column in 1290 Infinity II LC System triple-quadrupole mass spectrometry for the accurate quantitation of TCA cycle analytes.

Phospholipids in mouse embryo eye lens tissues were identified using AB SCIEX QTRAP 5500 – Linear Ion Trap Quadrupole LC/MS/MS coupled to a Shimadzu EXION HPLC using C18 column in reversed-phase approaches.

Established metabolomics panel in cell culture samples using LC/Q-TOF 6546 and Write HPLC information.

Accurate quantification of Non- Esterified Fatty acids was carried out by derivatization (write the information) and extraction using Biotage® Extrahera™ Classic (write Hamilton project information.

Possess in-depth knowledge of metabolite and lipid structures and their metabolic pathways, for the interpretation and integration of targeted metabolomics and lipidomics data.

Demonstrated leadership skills by fostering a collaborative and positive working environment with peers and associates, ensuring successful completion of research projects.

Contributed to the investigations exploring links to Stress, Emotional Regulation, and Cognitive Control in a Nonhuman Primate Model using6500 Triple Quad Mass Spectrometry-Based Biomarker Analysis.

Proficiently executed testosterone LC-MS/MS analyses to study the role of puberty on physical and brain development in a longitudinal study in male Rhesus Macaques.

I am an expert in reviewing literature and providing assistance in grant and funding applications. Additionally, I have a thorough understanding of GLP/GCP regulations.

Performed mass spectrometry analysis of drug-like candidate small molecules to explain pharmacokinetics/pharmacodynamics (PK/PD) studies in mice to explain maternal P7C3-A20 Treatment Protects Offspring from Neuropsychiatric Sequelae of Prenatal Stress

Skilled in optimizing sample preparation workflows for various biological matrices (human, animal tissues, cell cultures) utilizing protein precipitation, solid-phase extraction, and multi-phase extraction techniques.

Developed and Validated Cortisol awakening response and fractional exhaled nitric oxide in asthma.

Quantified Benzo thiourea Derivatives using mass spectrometry to Target the Secretory Pathway of the Human Fungal Pathogen Cryptococcus neoformans.

Contributed to protocol generation and SOP optimization for complex and routine LC-MS methods and scientific publications.