KSHAMA Patel

• Conducted literature review on NLRP3 inflammasome pathways, cytokine signaling (IL-1β, IL-18), and macrophage polarization in vascular inflammation, identifying research gaps and formulating hypotheses to advance understanding of vascular inflammation mechanisms.
• Performed cell culture experiments with macrophages and endothelial cells to investigate inflammasome activation in response to stimuli such as cholesterol crystals and oxidized LDL, contributing to insights on inflammatory responses.
• Utilized molecular assays including qPCR, ELISA, and Western blotting to quantify gene and protein expression associated with inflammatory signaling, enhancing knowledge of inflammation pathways.
• Analyzed experimental data using GraphPad Prism and R, quantifying inflammatory mediators and immune cell infiltration.
• Using C57BL/6 mice, performed in vivo experiments by injecting rAAV6 viral constructs (Ormdl1/3 and PIP5kα) to investigate their effects on sphingolipid and cholesterol levels through membrane protein regulation in the context of atherosclerosis.

• Accompanied providers during patient visits, accurately documenting assessments, physical exams, and medical histories in real time.
• Documented diagnostic results, procedures, treatment plans, medications, and follow-up instructions to enhance clinical decision-making.
• Analyzed patients’ prior history and test results to guide current medical decisions.
• Tracked pending lab and radiology results, facilitating timely patient care for providers.
• Navigated electronic medical record (EMR) systems to ensure accurate and organized patient documentation.
• Adapted to multiple medical specialties and terminology in fast-paced environments.

• Delivered direct patient care by assisting with daily living activities, mobility, and personal hygiene to enhance patient comfort and well-being.
• Monitored vital signs, weights, and overall physical, mental, and emotional conditions, promptly reporting abnormal findings or changes to the RN. Documented patient observations to maintain accurate and complete medical records.
• Facilitated patient transfers, transport, dressing changes, pulse oximetry, point-of-care testing, and application/removal of external monitoring devices and urinary Foley catheters to support effective treatment.
• Engaged in interdisciplinary meetings to inform and contribute to collaborative care planning for optimal patient outcomes.

Supported system maintenance and troubleshooting of technical issues, optimizing data workflows for improved efficiency. Assisted in quality assurance checks, ensuring data integrity across platforms. Collaborated with cross-functional teams to streamline processes and enhance user experience.

• Provided technical support via helpdesk software, resolving user issues efficiently.
• Collaborated with team members to troubleshoot hardware and software issues, enhancing overall operational effectiveness.
• Documented IT processes and procedures for user reference and training purposes.

• Conducted in vitro MSC therapy experiments, overseeing cell culture maintenance, treatment administration, and monitoring of cellular responses to evaluate therapy effectiveness.
• Conducted literature review on autism spectrum disorder (ASD) pathophysiology and mesenchymal stromal cell (MSC) therapy, identifying gaps in current research and informing experimental design.
• Collected and entered data from behavioral assessments, cell culture experiments, and clinical records to enhance accuracy and reliability of study results.
• Performed statistical analyses using software tools (e.g., SPSS, Excel) to quantify behavioral or cellular outcomes and assess treatment efficacy.
• Presented findings to peers and faculty, emphasizing methodology and potential clinical implications of MSC therapy for ASD.

• Assisted in behavioral analyses to investigate cognitive and neurological impairments.
• Contributed to data collection and analysis, supporting ongoing experiments and advancing research objectives.
• Investigated neurodegenerative mechanisms related to Alzheimer’s-like dementia.
• Presented research findings through a scientific poster to enhance community awareness.
• Enhanced understanding of collaborative laboratory practices and brain function research through active participation.