Kun Ho Kim

Self-motivated stem cell biologist with 6+years of experience in muscle research and expertise in stem cells. Strong independent research skills including design, execution of experiments and interpretation of experimental results asdemonstrated by many publications in peer-reviewed journals. Excellent in-vivo and in-vitro techniques along with strong skills in communication and organization to collaborate and work in a team environment

• Best Student Award, Medicinal Bioconvergence Research Center (2017)
• Merit-based Scholarship, Seoul National University (2017)
• Travel Award, Purdue University (2022)

1. Kun Ho Kim, Stephanie N. Oprescu, Madigan M. Snyder, Aran Kim, Zhihao Jia, Feng Yue, Shihuan Kuang. “PRMT5 is essential for muscle development as it mediates FoxO1 methylation and subcellular localization to regulate lipophagy in myogenic progenitors.” Cell Reports (2023).

2. Kun Ho Kim, Zhihao Jia, Madigan Snyder, Jingjuan Chen, Jiamin Qiu, Stephanie Oprescu, Xiyue Chen, Sabriya A Syed, Feng Yue, Bruno T. Roseguini, Anthony N. Imbalzano, Changdeng Hu, Shihuan Kuang. “PRMT5 links lipid metabolism to contractile function of skeletal muscles.” EMBO Reports (2023).

3. Jiamin Qiu, Feng Yue, Peipei Zhu, Jingjuan Chen, Fan Xu, Lijia Zhang, Kun Ho Kim, Madigan M. Snyder, Nanjian Luo, Fang Huang, W. Andy Tao, Shihuan Kuang. “FAM210A regulates cold-induced thermogenesis of brown adipocytes by modulating cristae remodeling." Nature Communications (2023).

4. Christopher K. Kargl, Zhihao Jia, Deborah A. Shera, Brian P. Sullivan, Lundon C. Burton, Kun Ho Kim, Yaohui Nie, Monica J. Hubal, Jonathan H. Shannahan, Shihuang Kuang, Timothy P. Gain "Angiogenic potential of skeletal muscle derived extracellular vesicles differs between oxidative and glycolytic muscle tissue in mice.” Scientific Reports (2023).

5. Jingjuan Chen, Feng Yue, Kun Ho Kim, Peipei Zhu, Jiamin Qiu, W. Andy Tao, Shihuan Kuang. FAM210A mediates an inter-organelle crosstalk essential for protein synthesis and muscle growth in mouse.” BioRxiv (2023).

6. Michael Belbis, Bohyun Ro, Luke Schepers, Kun Ho Kim, Kyroungrae Kim, Terence Ryan, Craig Goergen, Shihuan Kuang, Timothy Gavin, Bruno Roseguini, Daniel Hirai. “Effects of heat therapy on skeletal muscle interstitial oxygenation and exercise tolerance in HFpEF rats.” Physiology (2023).

7. Farrokh Sharifi, Kun Ho Kim, Sankar Renu, Zhihao Jia, Shihuan Kuang, Meng Deng. “Impact of Gamma-secretase Inhibitor RO-PLGA Nanoparticle on Obesity Parameters: An Obese Mouse Study.” Obesity (2022).

8. Madigan M. Snyder, Feng Yue, Lijia Zhang, Renjie Shang, Jiamin Qiu, Jingjuan Chen, Kun Ho Kim, Ying Peng, Stephanie N. Oprescu, Shan S. Donkin, Pengpeng Bi, and Shihuan Kuang. “LETMD1 is required for mitochondrialstructure and thermogenic function of brown adipocytes. FASEB (2021).

9. Naagarajan Narayanan, Zhihao Jia, Kun Ho Kim, Liangju Kuang, Paul Lengemann, Gabrielle Shafer, Victor Bernal-Crespo, Shihuan Kuang, and Meng Deng. “Biomimetic Glycosaminoglycan-based Scaffolds Improve Skeletal Muscle Regeneration in a Murine Volumetric Muscle Loss Model”, Bioactive Materials (2021).

10. Naagarajan Narayanan, Paul Lengamann, Kun Ho Kim, Liangju Kuang, Tiago Sobreira, Victoria Hedrick, Uma Aryal, Shihuan Kuang, and Meng Deng. “Harnessing Nerve-Muscle Cell Interactions for Biomaterials-based Skeletal Muscle Regeneration”, Journal of Biomedical Materials Research Part A (2021).

11. Kun Ho Kim, Jiamin Qiu, and Shihuan Kuang. “Isolation, Culture, and Differentiation of Primary Myoblasts Derived from Muscle Satellite Cell”, Bio-protocol (2020).

12. Alexander M. Loiben#, Kun Ho Kim#, Sharon Y. Soueid-Baumgarten#, Victor M. Aguilar#, Jonathan Chin Cheong, Ruth F. Kopyto, Paula Fraczek, Ern Hwei Hannah Fong, Rahul Mangal, Lynden A. Archer, and Benjamin D. Cosgrove. “Long-tern high-yield skeletal muscle stem cell expansion through staged perturbation of cytokine signaling in a soft hydrogel culture platform”, BioRxiv (2020).

“Therapeutic agent for immune cell migration-caused disease and method for screening same” Sunghoon Kim, Nam Hoon Kwon, Jin Young Lee, Kun Ho Kim. US 11378572B2 (2022)

1. “Prmt5 is essential for maintaining lipid metabolism in skeletal muscle via regulation of Atgl” presented at 7th Annual Diabetes Symposium (IND, USA). 2021

2. “Prmt5 is Essential for ATGL mediated Lipid Metabolism in Skeletal muscle Presented at LOUJA competition (Purdue University, USA). 2021

3. “PRMT5 catalyzes H4R3Me2s to mediate epigenetic suppression of Pnpla2 and regulate lipid metabolism in skeletal muscle” presented at LOUJA competition (Purdue University, USA). 2022

1. “tRNA-mediated enhancement of RSK/MSK signaling and its connection to tumorigenesis” presented at Gordon Research Conference (Galveston, TX, USA). 2017

2. "The Role of tetraspanin proteins in muscle stem cell function" Best Combined Poster Award at the American Society for Engineering Education (ASEE) St. Lawrence 2018 Section Conference (WA, USA). 2018

3. "Engineering biomaterial microenvironment to facilitate long-term, clinical-scale skeletal muscle Stem cell expansion" at Stem Cell Retreat at Cornell University (NY, USA). 2018

4. “The Indispensable Function of PRMT5 in the Control of Lipid Droplet Formation in Myogenic Progenitor Cells” presented at Health and Disease at Purdue University (IN, USA). 2020

5. “PRMT5 regulates lipid metabolism in skeletal muscle via epigenetic suppression of Pnpla2” presented at Experimental Biology Conference (Philadelphia, PA, USA). 2022

6. Impact of Gamma-secretase Inhibitor RO-PLGA Nanoparticle on Obesity Parameters: An Obese Mouse Study at obesity week conference (San Diego, CA, USA). 2022