Leslee Bertram
Lexington,KY
Summary
Healthcare and biopharmaceutical leader with more than 20 years of experience spanning oncology, bone marrow transplant, pediatric hematology/oncology, and neurological rare diseases. Doctor of Nursing Practice–prepared clinician with extensive expertise in patient services, reimbursement support, patient education, and specialty therapy access across complex healthcare environments. Proven success supporting healthcare providers, gene therapy centers, and multidisciplinary care teams in navigating payer coverage, prior authorization, appeals, coding, and reimbursement pathways for HCP-administered therapies, including oncology and rare disease products.
Demonstrated leadership across regional, multi-state territories throughout Kentucky, Tennessee, Ohio, West Virginia, and Indiana, with deep experience collaborating cross-functionally to improve patient access, therapy initiation, adherence, and provider education. Successfully supported and launched multiple specialty and rare disease therapies, including disease-modifying therapies for Duchenne muscular dystrophy and spinal muscular atrophy. Recognized for translating strategic initiatives into operational execution through strong stakeholder engagement, clinical credibility, relationship-building, and solutions-oriented leadership.
Known for influencing healthcare professionals, payer stakeholders, and internal cross-functional partners through exceptional communication, accountability, and business acumen. Brings a strong track record of driving patient-centered outcomes, leading educational initiatives, supporting field-based operations, and fostering collaboration and leadership across commercial, clinical, and access functions.
Overview
20
20
years of professional experience
1
1
Certification
Work History
Duchenne Account Manager-KY, TN, OH, and IN
Sarepta Therapeutics
2025.09 - Current
- Strategic account selling and management skills. Develop comprehensive territory/account/customer plans to drive achievement of desired objectives.
- Consistently demonstrates emphasis on the “total account call” insuring that all personnel in the account are educated on commercially available Sarepta products including gene therapy and phosphorodiamidate morpholino oligomers (PMOs).
- Educated healthcare professionals on significance of antibody assays and genetic testing for effective treatment selection.
- Develop strategy and execute tactics within key accounts in the rare neurology therapeutic area to establish, generate and expand market share.
- Proactively identifies business opportunities with assigned accounts and leads appropriate coordination of effort by the Sarepta Rare Neurology account team, evaluating operational effectiveness/readiness in key accounts.
- Gains deep knowledge of each assigned account through internal research and proactive gathering and integration of information from various stakeholders within the account, e.g. business model, relevant business metrics, unique challenges, and strategic goals.
Oncology Reimbursement Manager-KY and WV
Johnson & Johnson
2024.04 - 2025.09
- Collaborated with cross-functional partners to facilitate patient therapy initiation and adherence post-prescription.
- Educated healthcare professionals on product coverage, prior authorization, appeals process, and coding requirements.
- Addressed critical access and affordability issues for patients with a proactive approach.
- Gained expertise in HUB and specialty distribution channels to enhance practice and patient support.
Therapeutic Area Manager-KY, WV and TN
Genentech
2016.06 - 2024.04
- Therapeutic Area Manager – Neurological Rare Disease.
- Launched disease-modifying therapy (DMT) for people living with spinal muscular atrophy (SMA).
- Built strong rapport and trust with healthcare professionals in neuromuscular centers across Kentucky, Tennessee, and West Virginia.
- Identified treatment-naïve patients within the community and educated community healthcare providers on the importance of a DMT for patients living with SMA.
- Educated healthcare professionals and staff on the safety and efficacy of DMT, as well as administration guidelines.
- Worked collaboratively with healthcare professionals to ensure that once a prescription was written, the patient was able to access the therapy in a timely fashion.
- Worked collaboratively with cross-functional partners to ensure that thought leaders in our area were able to speak as subject matter experts in front of state Medicaid pharmacy review boards. This resulted in favorable coverage policies for the DMT.
- Educated healthcare providers and staff on access and reimbursement policies and procedures as they were published by payers.
- Therapeutic Area Manager – Oncology.
- Served as the primary point of contact for oncology products in hospital systems and community oncology practices in eastern Kentucky, and eastern Tennessee. Therapeutic areas of focus included HER2+ breast cancer, PD-L1+ non-small cell lung cancer, hepatocellular carcinoma, diffuse large B-cell lymphoma, follicular lymphoma, and basal cell carcinoma.
- Addressed and identified opportunities for pulling through local market strategies at the point of care.
- Launched multiple new products in oncology including products for HER2+ breast cancer and lymphoma.
- Led the end-to-end experience for assigned customers/accounts and was responsible for driving clinical and non-clinical decision-making at the point of care. Educated practitioners on topics including screening, testing, palliative care, as well as non-clinical education including reimbursement, contract awareness, patient advocacy, etc.
- Delivered education to health care providers regarding product information, appropriate use, and dosing and administration based on FDA-approved product information and formulary/pathway guidelines.
- Kept abreast of customer and healthcare industry trends. Initiated development actions to constantly adapt and grow capabilities, to increase impact.
Advanced Registered Nurse Practitioner
University of Kentucky
Lexington, KY
2011.06 - 2016.06
- Worked collaboratively with multidisciplinary team to provide advanced practice nursing care to children adolescents, and young adults with cancer in the inpatient and outpatient settings.
- Educated patients, families and caregivers on patient diagnosis and treatment plan,
- Member of the multidisciplinary care team responsible for management of patients in the pediatric cancer survivor clinic.
- Collaborated with division chief to provide medical management for ~50 patients with chronic ITP.
- Collaborated with leadership to devise initiatives for improving nursing satisfaction, retention and morale including implementation of the Association of Pediatric Hematology and Oncology Nurses (APHON) Chemotherapy/Biotherapy curriculum for nursing staff.
- Founder and past-president of the Lexington APHON Chapter.
- Planned and executed successful pediatric oncology nursing symposium beginning in 2014. This symposium continues to be an annual event.
- Led team in driving successful patient outcomes by prioritizing standard of care and best practices.
- Pediatric Clinical Instructor for the University of Kentucky College of Nursing.
- Preceptor for numerous APRN students during clinical rotations.
RN, Kentucky Children's Hospital
University of Kentucky
2009.10 - 2011.06
- Collaborated with healthcare team to quickly assess patients and deliver appropriate treatment while managing rapidly changing conditions.
- Educated patients, families and caregivers on diagnosis and treatment options, and disease process.
- Trained new nurses in proper techniques, standards of care, operational procedures and safety protocols.
- Managed patient care from admission to discharge.
RN, Pediatric Bone Marrow Transplant
Cincinnati Children's Hospital Medical Center
2009.05 - 2009.10
- Collaborated with healthcare team to quickly assess patients and deliver appropriate treatment while managing rapidly changing conditions.
- Educated patients, families and caregivers on diagnosis and treatment options, and disease process.
- Monitored patient reactions to drugs and carefully documented findings.
- Prepared patients for clinical procedures, providing reassurance and practical advice to ease concerns.
- Demonstrated compassionate communication skills, empathetically delivering difficult news to patients and families.
- Managed patient care from admission to discharge.
RN, Pediatric Oncology and Bone Marrow Transplant
Trustaff Travel Nurses
2007.12 - 2009.05
- Provided age-appopriate nursing care to infants, children and adolescents and young adults.
- Collaborated with healthcare team to quickly assess patients and deliver appropriate treatment while managing rapidly changing conditions.
- Addressed and answered questions for families regarding patient treatment, health and progress.
- Worked with a consistently positive, friendly bedside manner to enhance patient experiences during difficult times.
RN, Pediatric Oncology and Bone Marrow Transplant
Methodist Children's Hospital
2006.11 - 2007.12
- Collaborated with healthcare team to quickly assess patients and deliver appropriate treatment while managing rapidly changing conditions.
- Educated patients, families and caregivers on diagnosis and treatment options, and disease process.
- Monitored patient reactions to drugs and carefully documented findings.
- Prepared patients for clinical procedures, providing reassurance and practical advice to ease concerns.
- Demonstrated compassionate communication skills, empathetically delivering difficult news to patients and families.
- Managed patient care from admission to discharge.
RN, Medical-Surgical Oncology
South Georgia Medical Center
2006.07 - 2006.12
- Addressed and answered questions for families regarding patient treatment, health and progress.
- Worked with meticulous accuracy in administering patient medication according to correct, appropriate doses.
- Evaluated patients at prescribed times to assess conditions and monitor progress against treatment goals.
- Monitored, recorded, and reported symptoms or changes in patient conditions in a timely manner.
Education
Doctor of Nursing Practice -
University of Kentucky
Lexington, KY2015
Master of Science in Nursing -
Northern Kentucky University
Newport, KY2011
Bachelor of Science - Nursing
University of Kentucky
Lexington, KY2006
Skills
- Ability to quickly establish trust and credibility with leadership teams across health systems
- Excellent analytical skills and ability to think critically
- Ability to be flexible and receptive to change
- Ability to synthesize multiple points of view and accurately represent the view of both patients, healthcare providers and key stakeholders
- Demonstrated leadership and complex organizational skills
- Demonstrated commitment to diversity, integrity, responsibility, excellence, compassion, empathy, creativity and teamwork
- Extensive knowledge of medication access channels including pharmacy and medical benefit, buy and bill, & assignment of benefit across multiple sites of care
Certification
- ANCC-PNP, BC
Licenses
- RN: Kentucky/Multistate
- APRN: Kentucky
Timeline
Duchenne Account Manager-KY, TN, OH, and IN
Sarepta Therapeutics
2025.09 - Current
Oncology Reimbursement Manager-KY and WV
Johnson & Johnson
2024.04 - 2025.09
Therapeutic Area Manager-KY, WV and TN
Genentech
2016.06 - 2024.04
Advanced Registered Nurse Practitioner
University of Kentucky
2011.06 - 2016.06
RN, Kentucky Children's Hospital
University of Kentucky
2009.10 - 2011.06
RN, Pediatric Bone Marrow Transplant
Cincinnati Children's Hospital Medical Center
2009.05 - 2009.10
RN, Pediatric Oncology and Bone Marrow Transplant
Trustaff Travel Nurses
2007.12 - 2009.05
RN, Pediatric Oncology and Bone Marrow Transplant
Methodist Children's Hospital
2006.11 - 2007.12
RN, Medical-Surgical Oncology
South Georgia Medical Center
2006.07 - 2006.12
Doctor of Nursing Practice -
University of Kentucky
Master of Science in Nursing -
Northern Kentucky University
Bachelor of Science - Nursing
University of Kentucky