Summary
Overview
Work History
Education
Skills
Accomplishments
Publications
Extracurricular Activities
Presentationsandworkshops
Research
Certification
Affiliations
Timeline
Generic

LINTA MARUTHURETHU BIJU

Bensenville,Illinois

Summary

I am a fifth-year graduate student pursuing a Ph.D. in Chemistry with a strong academic background in Biochemistry, Molecular biology, Applied Chemistry, and Biophysics. At UIC, the central theme of my research is to understand the molecular mechanisms of photoconversion in photoreceptor proteins using spectroscopic and dynamic crystallography experiments. Experienced in recombinant DNA technology, expression in multiple hosts (E. coli, Pichia), maintaining cyanobacterial cultures, protein characterization using assays, spectroscopy, cryoEM, Cryo-crystallography, and room-temperature Laue serial crystallography. Worked on multiple projects involving photoreceptors, beta-lactamases, and membrane-associated proteins.

Overview

6
6
years of professional experience
1
1
Certification

Work History

Graduate Research

University of Illinois
Chicago, USA
08.2019 - Current
  • Understanding the structure, dynamics, and signaling mechanism of the photoreceptors
  • Expression, purification, and crystallization of soluble and membrane proteins
  • Sample preparation for single particle cryo electron microscopy
  • Edited and submitted protocols and other required research documentation
  • Presented scientific papers in meetings and at conferences
  • Supervised work of undergraduate researchers to help further studies.
  • Studied and analyzed completed research to write technical papers for faculty review and journal submission.
  • Maintained accurate records of all research activities including data collection, analysis.
  • Managed laboratory teams and delegated tasks to complete experiments.
  • Contributed to grant proposals seeking funding for future projects.

Teaching Assistant

Chicago, USA
08.2019 - Current
  • Supported students individually and in groups to carry out Organic Biochemistry experiments that are relevant to human health and healthcare
  • Instructed undergraduate students in laboratory techniques in General Chemistry and Biochemistry Laboratory courses (CHEM,123, 125, 455)
  • Conducted tutoring and review sessions to help students understand concepts and prepare for assessments
  • (CHEM 122, 124,130)
  • Carried out a special research-focused program for entering students in UIC STEM Initiative Co-Lab program
  • Conducted office hours weekly
  • Proctored and graded exams, quizzes, assignments and delivered constructive feedback to students on ways to improve

Assistant Teacher in Chemistry

St Thom Academy
India
01.2019 - 03.2019
  • Instructed Class XI and XII students on how to carry out Chemistry Laboratory experiments
  • Class XII Chemistry Lectures

Education

DOCTOR OF PHILOSOPHY CANDIDATE - CHEMISTRY

University of Illinois
Chicago, IL
01.2025

MASTER OF SCIENCE - CHEMISTRY

Mahatma Gandhi University
India
01.2018

BACHELOR OF SCIENCE - CHEMISTRY

Mahatma Gandhi University
India
01.2016

Skills

  • Biomolecular characterization
  • Protein structure determination
  • Polymerase Chain Reaction (PCR)
  • Molecular Cloning
  • Advanced molecular biology
  • Site-directed mutagenesis
  • Protein expression
  • Bacterial systems
  • Yeast systems
  • Soluble protein expression
  • Membrane protein expression
  • Protein purification
  • Protein crystallization
  • UV/Visible spectroscopy
  • Affinity chromatography
  • Ion-exchange chromatography
  • Size-exclusion chromatography
  • ÄKTA Pure FPLC systems
  • SDS-PAGE
  • Agarose gel electrophoresis
  • Protein biochemical assays
  • Protein functional assays
  • TLC
  • Distillation
  • Soap making
  • Natural product synthesis
  • Proteomics QC sample preparation
  • In-gel digestion
  • S-trap micro spin column digestion
  • Cryo-EM
  • CryoSPARC
  • Glow Discharger
  • Vitrobot
  • Clipping grids
  • X-ray crystallography
  • Data processing
  • Structure refinement
  • HKL2000
  • PHENIX
  • Coot
  • Pymol
  • Gnuplot
  • ImageJ
  • Computational chemistry

Accomplishments

  • 08/26/24, Student Presenter award for Poster Presentation at the American
  • 07/27/24, Urbach Travel Award for Poster presentation at the American Society of Photobiology
  • 03/01/22, Student Presenter Award for Oral presentation at Gordon Research Seminar.
  • 03/01/22, Gordon Research Conference Speaker Travel Award
  • 08/01/22, Student Presenter Award for Oral presentation at ACS Conference.
  • 04/01/22, Department of Chemistry, UIC Travel Award
  • 01/01/16, Best Postgraduate Student Award Winner.
  • 01/01/16, First Rank Holder in M.Sc. Applied Chemistry.
  • 01/01/13, Secured A1 GPA - 9.21/10 grade for B.Sc. Chemistry.

Publications

  • Biju, L., Wang, C., Kang, W., Tom, I., Kumarapperuma, I., Yang, X., and Ren, Z, 2022, inSi-tuX: On-chip Crystallization and Large-Scale Serial Diffraction at Room Temperature., JoVE, 10.3791/63022
  • Kumarapperuma, I., Joseph, K, L., Wang, C., Biju, L., Tom, I., Grébert, T., Partensky, F., Schluchter, W., Yang, X, 2022, Crystal structure and molecular mechanism of an E/F type bilin lyase-isomerase., Structure, http://doi.org/10.1016/j.str.2022.01.007

Extracurricular Activities

8th Kyu (Greenbelt) in Dragon Karate and Kobudo. Trained in Fabric and Glass Painting. Sports Captain at Holy Angels Model School, Pathanamthitta, Kerala (2009). Sports Champion at Holy Angels Model School, Pathanamthitta, Kerala (2010 - 2013).

Presentationsandworkshops

  • Poster presenter at 42nd Steenbock Symposium, 06/07/22, Wisconsin, Madison, Light Induced structural Changes and Allosteric Activation in a Far-Red Photoreceptor.
  • Speaker at 1st Annual Biophysical Student Research Symposium, 05/13/22, University of Illinois at Chicago
  • Attendee - Sample Preparation workshop for CryoEM, 04/12/22 - 04/14/22, PNCC, Portland, Oregon
  • Speaker at the Gordon Research Seminar on Photosensory Receptors and Signal Transduction (GRS), 03/26/22 - 03/27/22, Ventura Beach Marriott, Ventura, CA
  • Poster Presenter at the Gordon Research Conference on Photosensory Receptors and Signal Transduction, 03/27/22 - 04/01/22, Ventura Beach Marriott, Ventura, CA
  • Attendee - RIC Summer Workshop series - Introduction to R, 07/01/21
  • Oral presentation at CTriC 2018 National Seminar on Current Trends in Chemistry, 2016, Cochin University of Science and Technology

Research

  • Graduate Research, Xiaojing Yang, 08/01/19, Ongoing, Understanding the structure, dynamics, and signaling mechanism of the photoreceptors., Expression, purification, and crystallization of soluble and membrane proteins., Sample preparation for single particle cryo electron microscopy., Edited and submitted protocols and other required research documentation., Presented scientific papers in meetings and at conferences.
  • Masters Research, Dr. Vipin Ipe Thomas, 08/01/16, 04/30/18, Aromaticity of various transition states involved in SEAr Bromination, Chlorination, Sulphonation and Nitration reactions of benzene.
  • Masters Research, Dr. Rony Rajan Paul, 08/01/16, 04/30/18, Synthesis and characterization of few aldonitrones and ketonitrones.

Certification

  • 08/01/19, Vitrobot Mark IV Certification - PNCC, Oregon
  • 08/01/19, Autogrid Clipping Certification - PNCC, Oregon

Affiliations

  • 07/27/24, I performed a spectroscopic demo on photoreceptor proteins for undergraduate students in the ASP 2024 outreach program
  • 06/17/23, Conducted Demo Day at Baker Demonstration school
  • 01/01/16, Served as an Internal Complaints Committee member at CMS College, Kottayam, India.
  • 01/01/16, Served as The Association Treasurer - Department of Chemistry, CMS College, Kottayam.
  • 01/01/13, Served as a member of National Service Scheme (2013-2014).
  • 01/01/13, Served as Member of Bhoomithrasena (Earth's friend) scheme (2013-2014).
  • 01/01/13, Served as member of 'Janaseva 2015' conducted by NSS and Social Justice Department.

Timeline

Graduate Research

University of Illinois
08.2019 - Current

Teaching Assistant

08.2019 - Current

Assistant Teacher in Chemistry

St Thom Academy
01.2019 - 03.2019

DOCTOR OF PHILOSOPHY CANDIDATE - CHEMISTRY

University of Illinois

MASTER OF SCIENCE - CHEMISTRY

Mahatma Gandhi University

BACHELOR OF SCIENCE - CHEMISTRY

Mahatma Gandhi University
LINTA MARUTHURETHU BIJU