MANGESH KURADE
Harrison,NJ
Summary
Clinical research professional with over 5 years of experience managing IRB-regulated human and preclinical studies at academic medical center. Expertise in developing research initiatives from inception to execution, including budget management, regulatory compliance, and daily trial operations while adhering to GCP and HIPAA standards. Proven ability to enhance operational efficiency and reduce costs through data-driven strategies and strong financial oversight. Recognized for fostering collaboration among investigators, clinicians, and support staff to achieve project goals on time and within budget.
Overview
7
7
years of professional experience
Work History
Laboratory Manager
Columbia University, Department Of Psychiatry
New York, NY
11.2022 - Current
- Lead the clinical sample workflow for the MiSBIE study, coordinating the receipt, processing, and full chain-of-custody documentation for all participant specimens.
- Advanced the laboratory’s mitochondrial biomarker validation program, and bolstered a novel metabolic biomarker investigation.
- Manage and grow the MiSBIE biobank, maintaining meticulous freezer inventories, barcode tracking, and retrieval logs for thousands of diverse clinical specimens.
- Administer and QA the REDCap database, entering, cleaning, and updating key clinical data points to support real-time analyses.
- Draft study plans and SOPs for new projects and assay methodologies, ensuring regulatory and scientific rigor from project launch.
- Troubleshoot molecular assays (qPCR, ELISA), revise protocols, and minimize downtime in daily clinical operations.
- Partner with the Principal Investigator and finance team to forecast laboratory needs, build annual budgets, and track cost variances.
- Develop cost-allocation models and budget justifications for NIH and other federal grant submissions, strengthening funding proposals.
- Oversee vendor management—negotiating pricing, monitoring supply chains, and coordinating purchasing reports with the central finance office.
- Manage 20+ vendor relationships for consumables and equipment, proactively resolving supply chain issues before they disrupt workflows.
- Ensure HIPAA/privacy compliance by collaborating with Psychiatry IT, and implementing secure data-handling measures.
- Coordinate interdisciplinary projects focused on mitochondrial health, aligning timelines and deliverables across clinical, basic science, and data teams.
- Direct day-to-day research operations, prioritizing tasks, allocating resources, and maintaining seamless lab functionality.
- Navigate institutional administrative channels to expedite purchasing, service contracts, and facilities requests, streamlining overall workflow.
- Maintain IRB compliance, updating protocols, consent forms, and continuing-review submissions with zero audit findings.
- Train staff and interns in Good Laboratory Practices (GLP) and safety procedures, fostering a culture of quality, and continuous learning.
- Serve as the laboratory safety liaison, conducting inspections with Environmental Health & Safety (EH&S) to ensure full adherence to biosafety regulations.
Technician B
Columbia University College Of Physicians And Surgeons
New York, New York
12.2019 - 11.2022
- Supervising laboratory operations including day-to-day research operations, financial management, personnel training, and inventory control
- Maintaining Columbia Biobank for Translational Studies (CBTS), drafting IRB protocols for clinical studies, and personnel training.
- Leading projects involving novel approaches and troubleshooting obstacles to meet research goals.
- Fluent with Redcap and Epic applications for patient surveys and updating Biobank data as per research requirements.
- Complete responsibility for developing in-vivo models, training associated personnel, drafting IACUC protocols, overseeing colony maintenance, and corresponding cost management.
- Designing research protocols in adherence to studies proposed in grant applications.
- Assisting in grant application, literature survey, and cost assigning.
- Overseeing laboratory's essential regulatory aspects for clinical and pre-clinical studies.
- Coordinating with Clinical Trials team for laboratory compliance, sample processing, and personnel training.
- Validating/troubleshooting molecular assays to achieve research compliance and goals.
- Optimized operations and facilitated decision-making by examining problem-solving concepts, quantitative methods, and techniques.
- Maintaining lab safety protocols and ensuring timely updates with EH&S safety officers
- Supervising supplies ordering and negotiating prices with 15+ vendors to secure top-quality items at best possible pricing.
Research Associate
Locus Biosciences
Raleigh, NC
07.2019 - 09.2019
- Developed and executed pre-clinical infectious model in mice to test company's leading CRISPR-engineered bacteriophages.
- Executing all studies as double-blinded trials in coordination with third-party vivarium and CROs.
- Expanding pre-clinical models to achieve research standards in accordance with CROs and retaining costs in range of 30k+ per study.
- Responsibilities included developing new protocols and revising existing ones in adherence to IACUC set guidelines.
- Maintaining lab supplies and budgeting for upcoming projects.
- Gathered, arranged, and corrected research data to create representative graphs and charts highlighting results for presentations
Research Technician
University Of Vermont Medical Center
South Burlington, VT
01.2019 - 05.2019
- Assisted post-doctoral research fellows in maintaining cell lines and related in vitro work
- Coordinated with ICM staff in maintaining, genotypic and colony management for genetically altered mice and saving vivarium costs in range of 10K+
- Developed ELISA assays and flow cytometry samples as routine in vitro testing.
- Followed research protocols when gathering data and performing lab experiments
Education
Master of Science - Pharmacology And Toxicology
Long Island University
Brooklyn, NYBachelor of Science - Pharmaceutical Sciences
VIVA Institute of Pharmacy
Mumbai, IndiaSkills
- Clinical study and laboratory management
- Research administration and coordination
- Financial oversight
- Study design and data management
- Data interpretation and monitoring
- Cross-functional teamwork
- Inventory control
- In vivo studies and flow cytometry
- Literature review
- Client relations and communication
- Microsoft Office suite
- GraphPad Prism and R Studio
Accomplishments
- Kurade, M., et al., Mitochondrial and Stress-Related Psychobiological Regulation of FGF21 in Humans.medRxiv, 2025. (Nature Metabolism - Acceptance in Principle)
- Liu, C.C., et al., Immune cell mitochondrial phenotypes are largely preserved in mitochondrial diseases and do not reflect disease severity. bioRxiv, 2025: p. 2025.01.18.633635.
- Huang, Q., et al., The mitochondrial disease biomarker GDF15 is dynamic, quantifiable in saliva, and correlates with disease severity. Molecular Genetics and Metabolism, 2025: p. 109179.
- Kelly, C., et al., A platform to map the mind-mitochondria connection and the hallmarks of psychobiology: the MiSBIE study. Trends in Endocrinology & Metabolism, 2024. 35(10): p. 884-901.
- Castillero, E., et al., Decreased serotonin transporter activity in the mitral valve contributes to progression of degenerative mitral regurgitation. Science Translational Medicine, 2023. 15(677): p. eadc9606.
- Abramov, A., et al., Bioprosthetic heart valve structural degeneration associated with metabolic syndrome: Mitigation with polyoxazoline modification. Proceedings of the National Academy of Sciences, 2023. 120(1): p. e2219054120.
References
References available upon request.
Timeline
Laboratory Manager
Columbia University, Department Of Psychiatry
11.2022 - Current
Technician B
Columbia University College Of Physicians And Surgeons
12.2019 - 11.2022
Research Associate
Locus Biosciences
07.2019 - 09.2019
Research Technician
University Of Vermont Medical Center
01.2019 - 05.2019
Master of Science - Pharmacology And Toxicology
Long Island University
Bachelor of Science - Pharmaceutical Sciences
VIVA Institute of Pharmacy
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