Summary
Overview
Work History
Education
Skills
METHODOLOGIES DEVELOPED
Timeline
Generic

Mark Santangini (MLS ASCP)

Providence

Summary

Medical Technologist with extensive experience at Brown University Health, excelling in developing innovative laboratory methodologies. Proficient in LC-MS/MS and chromatography techniques and quality control processes. With years of experience troubleshooting and maintaining complex laboratory equipment

Overview

11
11
years of professional experience

Work History

Sr. Medical Technologist

Brown University Health - Toxicology
Providence
12.2018 - Current
  • Develop and validate new laboratory methodologies and techniques on multiple chromatographic and mass spectrum platforms
  • Serve as main point of contact for laboratory operations, maintain working relationships with vendors, collaborators, and physicians
  • Author and maintain all SOP laboratory documentation
  • Perform instrument start up and cleaning for all HPLC, LC-MS/MS instrumentation, including disassembling and cleaning of internal components, seals, and quadrupoles
  • Oversee daily operations including staffing, scheduling, QC/QA, and regulatory compliance with CAP, CLIA, and conforming to GxP(GLP, GDP)
  • Conduct review of all laboratory quality control processes, OOS, Levey-Jenning, maintenance and repair logs
  • Manage inventory and procurement of laboratory supplies for daily operations.
  • Maintain and troubleshoot all HPLC, LC-MS/MS, GC-MS, ICP-MS, AA, LC-QTOF instruments, including routine repairs, calibration, tuning, and preventative maintenance, hardware and software troubleshooting.

Medical Technologist

Rhode Island Hospital - Toxicology
Providence
06.2016 - 12.2018
  • Perform high complexity testing and analysis using manual and automated methods.
  • Conduct manual specimen preparation including hydrolysis, extractions (SPE, LLE), and derivatization.
  • Prepare manual reagents and buffers for analysis following all regulatory guidelines and requirements.
  • Perform instrument startup, tuning and routine cleaning of all laboratory equipment
  • Interpreted chromatographic and mass spectrometry data on GC/MS, LC-MS/MS, HPLC, and GC-FID platforms.

Student Technologist

Rhode Island Hospital Chemistry Department
Providence
06.2014 - 06.2016
  • Prepared specimens by receiving and loading them on automated immunoassay and chemiluminescence analyzers
  • Conduct specimen integrity review pre and post analysis

Education

Bachelor of Science - Chemistry with a concentration in Medical Technology

Rhode Island College
01.2016

MLS (ASCP) Certification -

01.2016

Skills

  • LC-MS/MS – Agilent 6420, 6460, Sciex 4500
  • HPLC – Waters Acquity w/ UV/VIS, Electrochemical detection
  • GC-MS – Agilent 7890B, 5975C
  • LC-QTOF – Sciex X500R
  • HS GC-FID – Agilent 7890B, 6975
  • ICP-MS – PerkinElmer NexION 350X
  • GFAAS – PerkinElmer PinAAcle900Z

METHODOLOGIES DEVELOPED

  • Copper, Zinc, Selenium in Serum: ICP-MS
  • Mercury in Urine and Whole Blood: ICP-MS
  • Buprenorphine and Norbuprenorphine in urine: LC-MS/MS
  • Opiates, Methadone, and Tramadol in urine: LC-MS/MS
  • Alcohols and Ethylene glycol in serum: Headspace GCFID
  • Antiepileptic drugs in serum: LC-MS/MS
  • Comprehensive Drug Screen in serum and urine: LC-QTOF
  • Vitamin B1(Thiamine pyrophosphate) in Whole Blood: LC-MS/MS

Timeline

Sr. Medical Technologist

Brown University Health - Toxicology
12.2018 - Current

Medical Technologist

Rhode Island Hospital - Toxicology
06.2016 - 12.2018

Student Technologist

Rhode Island Hospital Chemistry Department
06.2014 - 06.2016

Bachelor of Science - Chemistry with a concentration in Medical Technology

Rhode Island College

MLS (ASCP) Certification -

Similar Profiles

CREATE PROFILE
Mark Santangini (MLS ASCP)
Resume profile built at Resume-Now.com