Maryam Saifaldeen
Research Scientist In Molecular Biosciences
Doha
Summary
Skilled Research Scientist enthusiastic about supporting advancements of Scientific Research in Qatar. Passionate about increasing knowledge to drive growth and needed improvements. Ready to apply the knowledge and 11 years of international and local research experience in research development.
Work History
Qatar Research Leadership Program (QRLP)
Qatar Foundation
2013 - Current
- Participated in many research projects of different biomedical disciplinaries.
- Authored and co-authored peer-reviewed publications, contributing to the broader scientific community's understanding of broad topics.
- Conducted thorough literature reviews, and gained massive experience in designing, optimizing, executing and analyzing experiments and results.
- Collaborated with researchers and scientists to design and execute experiments.
- Trained and supervised junior students in laboratory protocols.
Head of CHLS-Lab Committee
Hamad Bin Khalifa University
2020 - 2021
- Helped meet changes in laboratory demands by recommending improvements to different systems or procedures.
- Demonstrated creativity and resourcefulness through the development of innovative solutions.
- Conducted regular reviews of operations and identified areas for improvement.
- Enforced rules and regulations to create a more productive and efficient laboratory work environment.
- Developed strong communication and enhanced group work and interaction between professors, staff and students to build healthy and positive relationships.
Site Manager at COVID-19 Quarantine Hotel
Red Crescent
2020 - 2020
- Led successful initiatives to ensure seamless organizational structuring during a pandemic crisis.
- Developed systems and procedures to improve operational quality and team efficiency and to reduce turnaround time.
- Collaborated with multidisciplinary teams (primary care providers, specialists, and other governmental authorities) to provide comprehensive healthcare services.
- Cultivated an environment of trust within the workplace through open communication, transparent decision-making, and empathy for team members.
- Mentored junior team members and allocated tasks and duties to each member.
- Educated patients and assisted residents with basic hygiene and healthcare needs.
Education
Doctor of Philosophy (PhD) - Genomics And Precision Medicine
04.2001 -
College of Health and Life sciences
Masters of Research (MRes) - Molecular And Cellular Biosciences
04.2001 -
- Faculty of Life Sciences
- MRes degree with Upper Second Class with Honors
Bachelor of Science (BSc) - Biomedical Sciences
04.2001 -
- Faculty of Natural Sciences
- Science Foundation Programme (1 Year) with a Distinction
- BSc degree with an Upper Second Class Honors
High School Diploma -
04.2001 -
Skills
Language (Arabic) - Native
undefinedLaboratory Experience
- PhD degree Dissertation Project
HBKU, Qatar. Supervised by Professor Johan Ericsson.
Dissertation Title: Identification of beta-TrCP1 E3 Ubiquitin Ligase as a Novel Regulator of the SCAP-mediated SREBP Pathway Activation.
- PhD Side Projects
HBKU, Qatar, Dr. Mustapha Aouida
Projects: Applications of the CRISPR/Cas9 Systems Beyond Gene Editing.
- Lab Rotations During the PhD program
HBKU, Qatar
Title: Engineering a reporter system to assess activities of CRISPR/Cas system platforms. Supervised by Dr Mustapha Aouida.
Title: Studying the effect of SCAP/SREBP interaction in the lipid metabolism regulatory pathway. Supervised by Professor Johan Ericsson.
- Master's Degree Research Project in Structural Biology
Imperial College of London, United Kingdom. Supervised by Dr Tiago Costa
Thesis Title: Tetracysteine tagging of TraA to understand the biogenesis and assembly of conjugative F-pilus
- Master's Degree Research Project in Molecular Parasitology
Imperial College of London, United Kingdom. Supervised by Professor Gloria Rudenko
Thesis Title: Understanding the dynamic ribosomal DNA transcription by RNA Polymerase I in Trypanosoma brucei using novel Fluorescent Timer
- Master's Degree Research Project in Molecular Microbiology
Imperial College of London, United Kingdom. Supervised by Professor Martin Buck
Thesis Title: Regulation of the Rtc RNA repair system in Escherichia coli
- Research Internship
Weill Cornell-Medicine, Qatar. Supervised by Dr. Nayef Mazloum
Project Title: Oxidative stress induction of pre-adipocyte cells to characterise genes responsible for the inflammatory response in diabetes
- Bachelor's Degree Research Project
University of Southampton, United Kingdom. Supervised by Dr. Joern Werner
Project Title: Biosynthesis of peptide using Escherichia coli as an expression system
Accomplishments
- CHLS Annual Students Research Forum
- Gulf Math Olympiad
- I am a researcher program - Qatar
Presentation titled: 'Identification of the Ubiquitin Ligase β-TrCP1 as a Regulator of the SREBP Pathway'.
First place of the best PhD student presentation
United Arab Emirates, Bronze medal (Second place)
Presentation titled: 'Surveillance of disease-causing bacterial growth on different surfaces'.
First place of the best movie and second place of the best presenters and project idea.
Publications
- Saifaldeen, M., Al-Ansari, D. E., Ramotar, D., & Aouida, M. (2020). CRISPR FokI Dead Cas9 System: Principles and Applications in Genome Engineering. Cells, 9(11). https://doi.org/10.3390/cells9112518
- Saifaldeen, M., Al-Ansari, D. E., Ramotar, D., & Aouida, M. (2021). Dead Cas9–sgRNA Complex Shelters Vulnerable DNA Restriction Enzyme Sites from Cleavage for Cloning Applications. The CRISPR Journal, 4(2), 275–289. https://doi.org/10.1089/crispr.2020.0134
- Sharari, S., Aouida, M., Mohammed, I., Haris, B., Bhat, A. A., Hawari, I., Nisar, S., Pavlovski, I., Biswas, K. H., Syed, N., Maacha, S., Grivel, J. C., Saifaldeen, M., Ericsson, J., & Hussain, K. (2022). Understanding the Mechanism of Dysglycemia in a Fanconi-Bickel Syndrome Patient. Frontiers in Endocrinology, 13. https://doi.org/10.3389/fendo.2022.841788
- Aouida M, Saifaldeen M, Al-Ansari DE, Taleb S, Hssain AA, Ramotar D. A CRISPR-based approach using dead Cas9-sgRNA to detect SARS-CoV-2. Front Mol Biosci. 2023 Jun 14;10:1201347. doi: 10.3389/fmolb.2023.1201347. PMID: 37388245; PMCID: PMC10300348.
Timeline
Hamad Bin Khalifa University - Doctor of Philosophy (PhD), Genomics And Precision Medicine
04.2001 -
Imperial College of London - Masters of Research (MRes), Molecular And Cellular Biosciences
04.2001 -
Southampton University - Bachelor of Science (BSc), Biomedical Sciences
04.2001 -
Al-bayyan Independent Secondary School - High School Diploma,
04.2001 -
Qatar Research Leadership Program (QRLP) - Qatar Foundation
2013 - Current
Head of CHLS-Lab Committee - Hamad Bin Khalifa University
2020 - 2021
Site Manager at COVID-19 Quarantine Hotel - Red Crescent
2020 - 2020
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