Matthew Comienski

• Led financial operations for four global clinical studies (hematology & oncology), managing $10M+ in site payments YTD and supporting accurate forecasting across multi-cycle study budgets.

• Conducted financial analysis on payment trends, variances, and reconciliation discrepancies, improving payment accuracy and reducing outstanding liabilities.

• Implemented and optimized Medidata Payments workflows, improving operational efficiency and standardizing financial processes across study teams.

• Built and maintained Excel-based trackers for invoice processing, approval flow, forecasting, and aging analysis to support financial decision-making.

• Trained cross-functional project teams on payment processes, budget reconciliation, and compliance expectations to ensure consistency across studies.

• Developed SOPs and tools that enhanced data accuracy, reduced processing redundancies, and strengthened operational compliance.

• Led sponsor-facing Investigator Grant calls weekly, presenting financial updates, resolving issues, and ensuring alignment between Finance, Clinical Operations, and external partners.

• Supported operational and financial components across three clinical studies by managing study documentation, budget-related items, and data accuracy across CTMS and eTMF systems.

• Prepared and maintained detailed trackers, meeting minutes, and action items to support forecasting, planning, and cross-functional decision-making.

• Assisted in budget reviews, financial documentation audits, and protocol deviation analysis to ensure compliance and accuracy in financial reporting.

• Collaborated with multicultural global teams to support site communications, financial documentation, and operational planning.

• Managed global payments for 250+ clinical sites, processing $5M+ in payments in 2020.

• Reconciled 80+ sites in 3 months, resolving over $1M in outstanding liabilities, improving accuracy in budget tracking and financial documentation.

• Analyzed weekly financial reports and data trends from CTMS and EDC systems to support operational decisions and forecasting.

• Reviewed contracts, budgets, and FMV terms to ensure compliance and accurate financial execution.

• Developed SOPs to standardize payment practices across regions, including LATAM, improving process consistency and audit readiness.