Years of Research Experience
Hi, I’m
MEGAN MARIE BIESINGER
Research Scientist
Holladay,Utah
Science does not know its debt to imagination.
Ralph Waldo Emerson
Summary
Innovative and passionate research scientist with an unique background in genetics and immunology identifying molecular patterns in complex tissues through designing experiments and producing data from advanced genomic and spatial technologies followed by bioinformatic analyses. Eager to increasing knowledge for myself and others to drive growth and needed improvements in the biomedical scientific field. Ready to learn more and experience research in a new ways.
Education
Icahn School of Medicine At Mount SinaiNew York, New York
Master of Science from Biomedical Sciences
09.2023
University Overview
- Thesis: Characterizing the immune microenvironment of type 1 diabetes using in situ spatial transcriptomics
Brigham Young UniversityProvo, Utah
Bachelor of Science from Genetics, Genomics, And Biotechnology
07.2021
University Overview
- Minor: Chemistry
Overview
9
2
Internships
6
Programming Certificates
Availability
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Work History
Van Andel Institute Graduate School
Mentored Researcher
01.2024 - 06.2024
Job overview
- Participated in a variety of research topics including epigenetics, metabolism, skeletal biology, and immunology
- Cell cultured colon cancer cells and induced specific cellular death pathways with clinical trial drug combinations, cultured stem cells prior to performing viral transfections, weighed mice in dietary study, isolated T cells from mouse spleen and lymph nodes, performed flow cytometry, and explored various sex specific gene isoform expression following T cell activation.
Icahn School of Medicine at Mount Sinai
Mentored Researcher
11.2021 - 09.2023
Job overview
- Characterized the immune niche and microenvironment of Type I Diabetes using in situ spatial transcriptomics from Veranome and 10X Genomics with a focus on major histocompatibility complex (MHC) composition
- Cyrosectioned tissue samples from OCT blocks, performed single cell bioinformatic data analyses, and collaborated with interdisciplinary teams to design a custom probe panel for spatial transcriptomics at subcellular resolution for human pancreas and tonsil
University of Kentucky
Research Assistant/Laboratory Technician
01.2021 - 06.2021
Job overview
- Utilized data from Bionano Genomic’s Saphyr and Next Generation Sequencing from Oxford Nanopore Technologies to compare structural variants identified using in haplotypes of the major histocompatibility complex and top genes associated with various neurodegenerative diseases
- Organized research materials, maintaining a well-ordered workspace conducive to productivity
Brigham Young University
Mentored Researcher
09.2019 - 12.2020
Job overview
- Generated data models, performed bioinformatic analyses, and assisted in producing a scientific review outlining results to test the hypothesis that there are metabolic differences in mitochondrial haplogroups known to have risk and protective associations to Alzheimer's Disease.
University of Canberra
Internship Abroad Researcher
02.2017 - 05.2017
Job overview
- Performed various research responsibilities including evolutionary analyses involving the number of vertebrae and bones in dorsal and anal fins in native Australian fish using X-rays, co-designed an experiment exploring the effects caffeine has on wildlife due to spilled beverages, gathered data on native and invasive plant species from the Outback to aid a PhD student in his ongoing ecological field research, and recorded wildlife that uses Outback waterholes leading to preservation of the waterholes.
Nelson Laboratories Inc.
Laboratory Analyst Intern
06.2016 - 08.2016
Job overview
- Tested medical equipment before approval for clinical use through a variety of methods including bacterial endotoxin testing, measuring particulates, bacterial and fungal identification, and logging tests regularly while observing work in cell culture, microbiology, and pharmaceuticals.
Jordan Academy for Technology and Careers
Biotechnologist
08.2015 - 06.2016
Job overview
- At a research symposium, presented independent research inducing the unfolded protein response in HeLa cells to explore the point of protein damage cells can undergo before inducing apoptosis
- Techniques included cell culture and western blots
- Studied the metabolism of tardigrades (water bears) to create a biotechnology design incorporating stimulating high metabolism in astronauts who spend excess time in space
- Won first place in State biotechnology design conference and participated in the following National conference.
Leadership Experience
Scientific Mentor, ASMP New York Academy of Sciences
- Once a week mentored third and fourth grade students at Chinese American Planning Council (CPC) at Pike St. through the New York Academy of Sciences in the After School Mentorship Program (ASMP). I worked with the directors in creating experiments to better teach specific scientific concepts. Fall 2022 held the theme “Water Wonders” and Spring 2023 “Light”
Skills
- Team Collaboration
- MS Office
- Sample Preparation
- Meticulous Record-Keeping
- Scholarly Research
- Data Analysis and Interpretation
- Data Collection and Organization
- Scientific Communication (Writing and Presentation)
- Mentoring
- Positive Attitude
- Public Speaking
- Goal Identification
- Results Interpretation
- Leadership Roles
- Strategic Planning
Certification
- Programming in R: Introduction to R
- Introduction to Data Visualization with ggplot 2
- Introduction to the Tidyverse
- Intermediate R
- Data Manipulation with dplyr
- Introduction to Shell
Languages
English
Native or Bilingual
Italian
Limited Working
Python (Coding)
Professional Working
R (Coding)
Full Professional
Accomplishments
- Presented and won poster competition as a first year PhD student
- First person to explore human tonsil and pancreas using 10X Genomics Xenium spatial analyzer using a custom probe panel I designed through collaborations with interdisciplinary scientists.
Affiliations
- New York Academy of Sciences
Timeline
Mentored Researcher
Van Andel Institute Graduate School
01.2024 - 06.2024
Mentored Researcher
Icahn School of Medicine at Mount Sinai
11.2021 - 09.2023
Research Assistant/Laboratory Technician
University of Kentucky
01.2021 - 06.2021
Mentored Researcher
Brigham Young University
09.2019 - 12.2020
Internship Abroad Researcher
University of Canberra
02.2017 - 05.2017
Laboratory Analyst Intern
Nelson Laboratories Inc.
06.2016 - 08.2016
Biotechnologist
Jordan Academy for Technology and Careers
08.2015 - 06.2016
Icahn School of Medicine At Mount Sinai
Master of Science from Biomedical Sciences
Brigham Young University
Bachelor of Science from Genetics, Genomics, And Biotechnology
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