Monara Angelim

Knowledgeable Scientist with robust background in Neuroscience and Immunometabolism and advanced analytical techniques. Notable for contributing to groundbreaking studies and publishing in peer-reviewed journals. Demonstrated expertise in data analysis, experimental design and teaching, showcasing strong problem-solving and critical thinking skills.

• Date of Birth: 10/31/87
• Nationality: Brazilian
• Visa Status: J-1

• Neuroscience
• Immunometabolism
• Nutrition

1. Castro P, (…) Angelim MKC, Vinolo MA. Hif-1 attenuates high-fiber diet-mediated proliferation and stemness of colonic epithelium. Gut Microbes. 2024 (in Review).

2. Valdivieso-Rivera F, Furino VO, Leher CE, Zanesco AM, Cruz MK, Gan FC, et al. E4BP4 Safeguards Brown Fat Mitochondria from Obesity-Induced Fragmentation via Ceramide Repression [Internet]. bioRxiv; 2025 [cited 2025 May 30]. p. 2025.05.19.652826. Available from: https://www.biorxiv.org/content/10.1101/2025.05.19.652826v1

3. Angelim MKSC. Mitochondrial Therapies for Neurodegenerative Diseases: Emerging Approaches and Challenges. PJS [Internet]. 2025; Available from: https://premierscience.com/pjs-25-757/

4. Oiticica PRA, Angelim MKSC, Soares JC, Soares AC, Proença-Módena JL, Bruno OM, et al. Using Machine Learning and Optical Microscopy Image Analysis of Immunosensors Made on Plasmonic Substrates: Application to Detect the SARS-CoV-2 Virus. ACS Sens. 2025 Feb 28;10(2):1407–18.

5. Hensel RC, Di Vizio B, Materòn EM, Shimizu FM, Angelim MKSC, de Souza GF, et al. Enhanced performance of impedimetric immunosensors to detect SARS-CoV-2 with bare gold nanoparticles and graphene acetic acid. Talanta. 2025 Jan 1;281:126903.

6. Regina-Ferreira L, Valdivieso-Rivera F, Angelim MKSC, Menezes Dos Reis L, Furino VO, Morari J, et al. Inhibition of Crif1 protects fatty acid-induced POMC neuron-like cell-line damage by increasing CPT-1 function. Am J Physiol Endocrinol Metab. 2024 May 1;326(5):E681–95.

7. Angelim MKSC, Moraes-Vieira PM. Glycolysis modulates efferocytosis in a noncanonical manner. Nat Metab. 2023 Feb 16;1–2.

8. Aguiar CF, Corrêa-da-Silva F, Gonzatti MB, Angelim MK, Pretti MA, Davanzo GG, et al. Tissue-specific metabolic profile drives iNKT cell function during obesity and liver injury. Cell Reports. 2023 Jan 31;42(1):112035.

9. Materón EM, Gómez FR, Almeida MB, Shimizu FM, Wong A, Teodoro KBR, Angelim MKSC,et al. Colorimetric Detection of SARS-CoV-2 Using Plasmonic Biosensors and Smartphones. ACS Appl Mater Interfaces. 2022 Dec 14;14(49):54527–38.

10. Rodrigues PB, Gomes GF, Angelim MKSC, Souza GF, Muraro SP, Toledo-Teixeira DA, et al. Impact of Microbiota Depletion by Antibiotics on SARS-CoV-2 Infection of K18-hACE2 Mice. Cells. 2022 Aug 18;11(16):2572.

11. Silva PB da, Silva JR da, Rodrigues MC, Vieira JA, Andrade IA de, Nagata T, Angelim MKSC, et al. Detection of SARS-CoV-2 virus via dynamic light scattering using antibody-gold nanoparticle bioconjugates against viral spike protein. Talanta. 2022 Jun 1;243:123355.

12. Soares JC, Soares AC, Angelim MKSC, Proença-Modena JL, Moraes-Vieira PM, Mattoso LHC, et al. Diagnostics of SARS-CoV-2 infection using electrical impedance spectroscopy with an immunosensor to detect the spike protein. Talanta. 2022 Mar 1;239:123076.

13. Ratelade J, Klug NR*, Lombardi D*, Angelim MKSC*, Dabertrand F, Domenga-Denier V, et al. Reducing Hypermuscularization of the Transitional Segment Between Arterioles and Capillaries Protects Against Spontaneous Intracerebral Hemorrhage. Circulation. 2020 Jun 23;141(25):2078–94.

14. Arruda NBM de, Silva LM de L, Araújo ACR de, Silva AEAO e, Angelim MKSC, Araújo AJS de, et al. Associação entre o tempo de internação e indicadores de massa muscular em idosos hospitalizados / Association between length of hospital stay and muscle mass indicators in hospitalized elderly. Brazilian Journal of Development. 2020 Apr 28;6(4):21832–47.

15. Angelim MKSC, Maia LMS de S, Mouffle C, Ginhoux F, Low D, Amancio-Dos-Santos A, et al. Embryonic macrophages and microglia ablation alter the development of dorsal root ganglion sensory neurons in mouse embryos. Glia. 2018;66(11):2470–86.

16. Boeri J, Le Corronc H, Lejeune FX, Le Bras B, Mouffle C, Angelim MKSC, et al. Persistent Sodium Current Drives Excitability of Immature Renshaw Cells in Early Embryonic Spinal Networks. J Neurosci. 2018 Aug 29;38(35):7667–82.

17. Cardoso HD, dos Santos Junior EF, de Santana DF, Gonçalves-Pimentel C, Angelim MK, Isaac AR, et al. Omega-3 deficiency and neurodegeneration in the substantia nigra: involvement of increased nitric oxide production and reduced BDNF expression. Biochim Biophys Acta. 2014 Jun;1840(6):1902–12.

18. Monteiro HMC, de Lima e Silva D, de França JPBD, Maia LMS de S, Angelim MKC, dos Santos AA, et al. Differential effects of physical exercise and L-arginine on cortical spreading depression in developing rats. Nutr Neurosci. 2011 May;14(3):112–8.

19. Maia LMSS, Amancio-dos-Santos A, Duda-de-Oliveira D, Angelim MKC, Germano PCP, Santos SF, et al. L-Arginine administration during rat brain development facilitates spreading depression propagation: evidence for a dose- and nutrition-dependent effect. Nutr Neurosci. 2009 Apr;12(2):73–80.