Morteza Rajabi

I'm a motivated and enthusiastic researcher with a strong background in molecular genetics and a keen interest in understanding the molecular mechanisms of human diseases. My primary research interests include cancer biology, molecular genetics, gene regulation, and the development of innovative diagnostic and therapeutic strategies.

My M.Sc. thesis focused on the effects of Epirubicin on the expression of miR-143-3p and miR-145 in MCF7 and MDA-MB231 breast cancer cell lines. Through this project, I gained valuable experience in experimental design, mammalian cell culture, RNA extraction, real-time PCR, gene expression analysis, and scientific data interpretation.

Currently, I'm investigating the antitumor effects of 4T1-derived exosomes enriched with miR-124 in a mouse model of breast cancer, with the goal of understanding the therapeutic potential of exosome-based microRNA delivery for cancer treatment.

Through my academic and research experience, I've developed strong skills in experimental design, molecular biology techniques, and data analysis. I am seeking a Ph.D. opportunity to further expand my research expertise and contribute to meaningful discoveries in biomedical science.

• Rajabi, M., Mohammadi, N.G., Mombeyni, M. et al. Epirubicin-Induced Upregulation of miR-143-3p and miR-145 Enhances Cytotoxicity in MCF-7, MDA-MB-231, and BT-474 Breast Cancer Cell Lines. Biochem Genet. 2026. DOI:10.1007/s10528-026-11408-z.
• Javadian M, Zeinali T, Rajabi M, Mehrasa Z, Boogari M, Ramezani F, et al. Exosomal lncRNAs as molecular switches driving macrophage-tumor co-evolution in breast cancer. Clin Exp Med. 2026. DOI:10.1007/s10238-026-02199-z.
• Najafi A, Dastbaz E, Mehrabani A, Rajabi M, et al. Identifying Differentially Methylated Sites for Methylation-Sensitive qPCR-based NIPT of Trisomies 13 and 18, Advanced Biomedical Research, 2025. DOI:10.4103/abr.abr_37_25.
• Rajabi M, et al. Primary progressive multiple sclerosis: New therapeutic approaches. Neuropsychopharmacol Rep. 2025. DOI:10.1002/npr2.70039.
• Jamshidi, N, khodarahmi , P, Rajabi, M, et al. Comparative investigation of miRNA422a serum expression level in healthy and metastatic lung cancer Patients by Real Time PCR method . Life Sciences Student Journal, 2023. DOI:10.22034/LSSJ.2023.1.59.
• Ghandehari Z, Salahi Ardekani O, Hammami B, Arabi M, Rajabi M, et al. Clinical findings and mortality rate of patients with multiple myeloma following COVID-19 infection: Report from Iranian Network for Research in Viral Diseases (INRVD). Iran J Virol. 2023.

• Rajabi M, et al. Epirubicin-Induced Alterations in miR-143-3p Expression in MCF-7 and MDA-MB-231 Breast Cancer Cells. Poster presentation. 9th International USERN Congress and Prize Awarding Festival, Medical University of Plovdiv, Plovdiv, Bulgaria; November 2024.
• Rajabi M, Gholyaf E, et al. Expression Alteration and Function of Small Non-Coding RNA in Retinoblastoma. Poster presentation. Second International Congress of Cancer Genomics (CGC2024), Tehran, Iran; October 2024.
• Rajabi M, Ghadyani F, Deldadeh N, Kia MM, Siadat SD. The Effect of Probiotics on Lung Cancer and Its Relationship with COVID-19. Poster presentation. 6th International and 18th Iranian Genetics Congress, Shahid Beheshti University, Tehran, Iran; July 2024.
• Rajabi M, Yavoddoost S. A Review on the Effect of gyrC Gene on the Virulence and Antibiotic Resistance of Pseudomonas aeruginosa. Essay presentation. 7th International Congress on Biomedicine (ICB2023), Tehran, Iran; November 2023.
• Nazari A, Rajabi M, et al. Genetics and Epigenetics of Hodgkin's Lymphoma. Oral presentation. Second International Congress of Cancer Genomics (CGC2024), Tehran, Iran; October 2024.
• Deldadeh N, Rajabi M, et al. Targeted Therapy of Kidney Cancer. Poster presentation. Second International Congress of Cancer Genomics (CGC2024), Tehran, Iran; October 2024.

• Nazari A, Osati P, Fakhry SS, Akhound-Attar M, Pazhouhesh Far N, Karimi MS, Ebrahimi N, Haji-Fattahalha M, Reza Raef A, Rajabi M. Prostate Cancer and Noncoding RNAs: A Focus on miRNAs, lncRNAs, and circRNAs. In: Prostate Cancer: Molecular Events and Therapeutic Modalities. Springer Nature; 2024. pp. 183–201. DOI:10.1007/978-981-97-4612-6_8. (Book chapter)
• Rajabi M, et al. Genetics and Its Association with Neurological Disorders. In: Genetic and Its Association with Neurological Disorders. Dr. Mehdi Nasiri (Ed.). 2024.
• Naderimotlagh A, Talebzadeh S, Ghasiri F, Behzadi M, Rajabi M, Fard N, Rashid M, Kargar M, Siadat SD, Aslani J, Sharifzadeh M. Association of Virus with Colorectal and Liver Cancer. In: Association of Virus with Colorectal and Liver Cancer. 2024.

• CRISPR Gene Editing in Human Diseases with a Focus on Cancer: A Comprehensive Review

• Research Methodology & Proposal Writing Workshop
• Meta-analysis Workshop
• Introductory R Programming Workshop
• FlowJo Software Workshop
• Medical Diagnostic Laboratory Techniques Workshop