Noah Jacobs-Rebhun
Brooklyn,New York
Summary
Analytical Researcher with excellent communication skills and 3+ years of educational and hands-on experience in Cell & Gene Therapy. Adaptive team player with in-depth knowledge of data collection, confidential document control and problem-solving.
Overview
4
4
years of professional experience
Work History
Research Associate II
Bluerock Therapeutics
06.2021 - Current
- Responsible for the generation, CRISPR screening, maintenance, and characterization of multiple edited iPSC cell lines in parallel
- Tasked with the education, mentoring, management, and general oversight of a student enrolled in the emerging talent program
- Designed and Engineered methods for transition of CRISPR clone screening workflow into an automated format to optimize workflow efficiency and save FTE hours
- Independently initiated a research collaboration between Integrated DNA Technologies and Bluerock therapeutics
- Generated centralized repository for all team-specific protocols including wet and dry lab procedures, vendor procurement, and CRO requests.
Graduate Research Assistant
University of Vermont Larner College of Medicine
06.2019 - 05.2021
- Stafford Laboratory for Neuropharmacology and Chromatin Dynamics, Evaluating H3K36 Methyltransferase Activity in Neurodevelopmental Disease, Tasked with the characterization of methyltransferase enzymatic function on the epigenome in the context of neurodevelopmental diseases such as pediatric brain tumors and autism spectrum disorders
- Responsible for culture of previously derived primary pediatric brain tumor cell lines as well as HEK293 cells
- Design and perform CRISPR-Cas9 mediated knockout of methyltransferase genes to assess effect on methylation pattern in the epigenome
- Analyze impact of manipulating H3K36 methyltransferase activity on neurodevelopment disease models such as histone modifications, cell viability and other phenotypes.
Education
Master of Science - Pharmacology
University of Vermont Graduate College
Bachelor of Science - Biological Sciences
University of Vermont College of Arts and Sciences
Skills
- Professional Skills
- Cell & Gene Therapy
- Communication
- DNA Sequencing
- Process Improvement
- Aseptic Tissue Culture
- Data Presentation
- Molecular Assays
- Microsoft Office
- CRISPR Editing
- Strategy Development
- Workflow Optimization
Timeline
Research Associate II
Bluerock Therapeutics
06.2021 - Current
Graduate Research Assistant
University of Vermont Larner College of Medicine
06.2019 - 05.2021
Master of Science - Pharmacology
University of Vermont Graduate College
Bachelor of Science - Biological Sciences
University of Vermont College of Arts and Sciences
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