Summary
Overview
Work History
Education
Skills
Timeline
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Sinal Patel

Research Associate
Framingham,MA

Summary

Passionate researcher with several years of biotech/biopharma experience in the Boston area. Extensive background in cancer/immune-oncology research with strong skills in tumor processing, cell culturing, ELISAs, immunofluorescence imaging, and microscopy. Seeking career opportunities to grow as a scientist and as a leader with hopes to greatly contribute to the advancement of science.

Overview

13
13
years of professional experience

Work History

Research Associate II

Xsphera Biosciences, Inc.
02.2022 - Current
  • Processed 100+ patient tumors such as CRC, NSCLC, and RCC into spheroids for downstream analyses
  • Created and maintained 200+ 3D cell-cultures of patient-derived organoids and cancer cell lines
  • Developed and refined several immunoassays to be implemented with company’s major platform including Immunofluorescence Staining, ELISAs, and RNA isolations
  • Designed, led, refined, and presented study designs/experiments for eventual incorporation into workflow
  • Utilized NIS-microscopy imaging to capture cytotoxicity via staining techniques
  • Calculated drug concentrations for accurate treatment schemes in accordance with platform capabilities
  • Performed PBMC and CAR-T isolations, ELLA experiments, and flow cytometry
  • Maintained physical and electronic lab inventory and general lab maintenance.

PCR Scientist

Eurofins USA Clinical Diagnostics
10.2020 - 01.2022
  • Performed RNA extraction on human SARS-CoV2 virus using automated liquid handling systems
  • Utilized rt-PCR and q-PCR on extracted nucleic acids for RNA amplification via the Agilent Bravo Plating instrument and performed quantitative analysis of data
  • Validated new instruments and improved extraction methods to increase accurate throughput
  • Trained junior lab members on CLIA protocols to maintain proper lab certification
  • Maintained instruments via daily checks and troubleshooted PCR instruments through QA/QC protocols
  • Maintained GLP/GMP for R&D method validation.

Pharmacy Technician

CVS Pharmacy
03.2019 - 12.2020
  • Prepared hundreds of medical prescriptions for patients through efficient communication with pharmacists
  • Accurately completed patient paperwork relating to prescription filling and insurance claims
  • Ensured availability of drugs by maintaining the physical inventory and ordering/stocking when necessary
  • Adhered to pharmacy’s safety rules by following infection-control procedures, policies, and regulations.

Laboratory Technician

Indian Red Cross Society
10.2012 - 08.2013
  • Drew blood samples via direct venipuncture from the patient’s finger or vein
  • Conducted chemical analysis of biological fluids including blood and urine samples via several methods
  • Supervised and instructed other technicians and training new employees/students
  • General blood bank work including specimen collection, procurement, processing, testing, cross matching, transfusion, component separation, and maintaining proper storage conditions
  • Performed testing such as ICT/DCT and ELISA on specimens positive for HIV, HBsAg, MP, etc.

Education

BSc in Microbiology -

Sardar Patel University
Anand, Gujarat
08.2014

Skills

  • General lab Skills: micro-pipetting, aseptic techniques, microscopy/imaging, lab upkeep/maintenance, electronic and physical notebooking, drug preparation
  • Assays: immunofluorescence imaging, ELISA, flow cytometry, RNA isolations, cellular staining, RT-PCR, qPCR, ELLA, PBMC and CAR-T isolations, mouse and patient tumor processing, mechanical and enzymatic digestion of tumors
  • Personal Skills: strong communication, teamwork, leadership and effective delegation, curiosity and asking questions, strong time management
  • Background: mom of a 2-year-old daughter, hoping to earn Masters degree in biotechnology, owner of a fashion business
  • Critical thinking
  • Organizational skills
  • Problem solving
  • Decision making
  • Protocol development
  • Cross-Functional Teamwork

Work Type

Full Time

Work Location

On-SiteHybrid

Timeline

Research Associate II

Xsphera Biosciences, Inc.
02.2022 - Current

PCR Scientist

Eurofins USA Clinical Diagnostics
10.2020 - 01.2022

Pharmacy Technician

CVS Pharmacy
03.2019 - 12.2020

Laboratory Technician

Indian Red Cross Society
10.2012 - 08.2013

BSc in Microbiology -

Sardar Patel University

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Sinal PatelResearch Associate