OLGA MIKHAYLICHENKO
Martinez,CA
Summary
Ph.D.-level molecular geneticist with over a decade of global research expertise. Proven track record in product development, molecular diagnostics, and innovation. Proficient in cultivating strong internal and external relationships, resulting in successful scientific collaborations and partnerships that drive impactful outcomes for patients. Committed to advancing strategic goals and enhancing patient outcomes through effective collaboration and innovation.
Overview
7
7
years of professional experience
1
1
Certification
Work History
Staff Scientist, External Collaborations
Bio-Rad Laboratories
2023.01 - Current
- Leading 10+ external collaborations with industry and academic partners focusing on digital PCR (dPCR) applications in Reproductive Health in close collaboration with Scientific Affairs.
- Generating and curating scientific content for oral and poster presentations at international and domestic conferences resulting in 6 peer-reviewed abstracts and 1 journal submission.
- Contributed to the development of intellectual property and patents, safeguarding the organization''s competitive edge in scientific innovation.
- Assisting Market & Business Development groups in identification of new technology application opportunities and carrying out on-demand R&D due diligence analysis, contributing to $1M+ corporate investment decisions.
- Organizer and host of monthly Global R&D Forum featuring presenters from various areas of Clinical Diagnostics Business Unit and invited guest speakers with 500+ registered attendees.
Senior Scientist, External Collaborations
Bio-Rad Laboratories
2021.01 - 2023.01
- Completed cell-free DNA size selection technology evaluation for internal product development under tight deadlines and on budget.
- Managed 5+ external collaborations with industry and academic partners by providing experimental design, assay development and dPCR & NGS data analysis expert support.
- Organized on-site and remote technology-focused workshops and training visits for external partners and KOLs.
Scientist I, Process Development
Myriad Women's Health
2020.01 - 2021.01
- Integrated novel, automated DNA quantification method into CLIA production workflow.
- Supported quality control assay development for NIPT pipeline in collaboration with Manufacturing and Data Science teams.
- Performed complex troubleshooting in CLIA laboratory under time pressure.
Postdoctoral Molecular Biologist
King's College London
2018.01 - 2020.01
- Profound NGS expertise resulted in successful establishment of complete (sample to data processing) genomic pipelines for the School of Cardiovascular Medicine, allowing to secure $3 million in grant funding.
- Successfully established 5+ productive collaborations with medical doctors, physiologists and computer scientists within the School of Cardiovascular Medicine.
Education
Doctor of Philosophy - Molecular Biology
Heidelberg University
Heidelberg, Germany10.2017
Master of Science - Molecular Genetics
Moscow State University
Moscow, Russia06.2012
Skills
- Strong analytical skills and critical thinking capacity.
- Extensive experience with NGS and dPCR assay development including low input material quantification and library preparation from cell-free DNA.
- Operation, troubleshooting and maintenance of next-generation sequencers (Illumina NextSeq, Novaseq, PacBio Sequel II) and real-time PCR instruments.
- Molecular biology: western blot, chromatin immunoprecipitation, luciferase assay, PCR (including long range PCR, multiplex PCR, qPCR, dPCR), bacterial transformation, molecular cloning.
- Cell biology: cell culture techniques, transfection, fluorescence-activated cell sorting, confocal microscopy imaging.
- Design and execution of feasibility and guardbanding studies, SOP preparation, phase exit report preparation.
- Project management: project documentation, Kanban board management, Gantt chart organization & tracking, Jira. Automation: Basic principles of automated liquid handler operation (Beckman, Tecan, Integra).
- Data analysis: Familiar with Unix computational environment, bash scripting, R and python for data visualization.
- Marketing: market size analysis, marketing materials generation, KOL outreach and relationship building.
- Presentation skills: Excel at presenting complex scientific data & concepts to audiences with diverse backgrounds
- Leadership and Mentoring: proven track record of supervising, supporting and guiding junior team members toward project completion and professional development in industry and academic roles.
Keywords
- Product Development
- Next-Generation Sequencing
- Molecular Diagnostics
- Leadership
- Cross-functional Innovation
- Collaborations & Partnerships
- Scientific writing & presentation
- Scientific/Medical Affairs
Certification
mini-MBA, Biopharma Innovation | Rutgers Business School (Feb 2024 - May 2024)
Certification course focusing on commercialization, FDA regulations, market strategies, financial decision-making, supply chain management, strategic alliances, intellectual property, ethics, and innovation in biopharma
Selected Publications
- Mikhaylichenko, O., et al. Single Well Multiplex Droplet Digital PCR 22q11.2 Microdeletion Assay for Prenatal Diagnosis and Newborn Blood Spot Screening (2024). Abstracts of the ISPD 27th International Conference on Prenatal Diagnosis and Therapy, 18-21 June 2023. Journal of Prenatal Diagnosis. DOI: 10.1002/pd.6488.
- Ramesh., M., ... Mikhaylichenko, O., et al. A novel, iteratively designed and highly multiplexed droplet digital PCR assay for non-invasive prenatal screening (2023). Genetics in Medicine Open. https://doi.org/10.1016/j.gimo.2023.100682.
- Camargo, L., ... Mikhaylichenko O., et al. (2024). Protein disulfide isomerase-mediated transcriptional upregulation of Nox1 contributes to vascular dysfunction in hypertension. Journal of Hypertension. doi: 10.1097/HJH.0000000000003677.
- Papadopoulos, A., Chalmatzi, A., Mikhaylichenko, O., et al. (2020). Combined transcriptomic and phosphoproteomic analysis of BMP4 signaling in human embryonic stem cell. Stem Cell Research. doi: 10.1016/j.scr.2020.102133.
- Mikhaylichenko, O., et al. (2017). The degree of enhancer or promoter activity is reflected by the levels and directionality of eRNA transcription. Genes & Development. doi: 10.1101/gad.308619.117
Timeline
Staff Scientist, External Collaborations
Bio-Rad Laboratories
2023.01 - Current
Senior Scientist, External Collaborations
Bio-Rad Laboratories
2021.01 - 2023.01
Scientist I, Process Development
Myriad Women's Health
2020.01 - 2021.01
Postdoctoral Molecular Biologist
King's College London
2018.01 - 2020.01
Doctor of Philosophy - Molecular Biology
Heidelberg University
Master of Science - Molecular Genetics
Moscow State University
mini-MBA, Biopharma Innovation | Rutgers Business School (Feb 2024 - May 2024)
Certification course focusing on commercialization, FDA regulations, market strategies, financial decision-making, supply chain management, strategic alliances, intellectual property, ethics, and innovation in biopharma
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