Summary
Overview
Work History
Education
Skills
Websites
Recognitioncertifications
Publications
Volunteer Experience
Timeline
Generic

Prashasnika Gehlot

Houston,Texas

Summary

PhD - trained professional with seven years of industry experience and prior experience in academic settings with complex scientific project design and management. Robust drug discovery experience spanning from early-stage discovery research to life cycle management. Significant pre-clinical model development, clinical and translational research project management with responsibilities that include team management, managing multiple stakeholder collaborations, operations, and financial management.

Overview

14
14
years of professional experience

Work History

Director, Research Planning & Development

MD Anderson Cancer Center
Houston, Texas
01.2023 - Current
  • Scientific Management/Collaborations: Direct and lead 6 cross-functional teams of different functional groups focusing on clinical early discovery small molecule projects
  • Collaborate with directors, scientists, project leaders, and associate teams to identify and recommend strategic opportunities that drive scientific discovery and the development of novel therapeutics
  • Excel in fostering and sustaining strategic partnerships and collaborations with external research organizations, driving impactful and innovative outcomes
  • Proactively identify challenges, lead the team in developing solutions, and create contingency and troubleshooting plans to ensure seamless project execution
  • Effectively communicate project status updates, address inquiries, troubleshoot challenges, and clearly define scientific goals and deliverables for complex projects
  • Organized department-wide events to strengthen cross-functional team collaboration, enhancing team communication and engagement
  • Developed a standardized meeting template for the division and collaborated with other leaders to gather feedback to ensure successful implementation
  • Administrative/Budget: Provided administrative oversight of daily operations, managing a department of 50 employees, including performance review and promotions involvement with division leaders
  • Conducted regular assessments of scientific and market opportunities, identifying portfolio gaps and proposing strategic solutions
  • Coordinated departmental capital equipment requests and managed requisitions, ensuring timely procurement and resource allocation
  • Built and maintained strong relationships with key external and internal stakeholders to ensure project success and alignment with organizational goals
  • Monitored and evaluated the progress of multiple research projects, providing oversight and guidance on research activities
  • Trained teams on project management software and tools, enhancing efficiency and collaboration across projects
  • Secured funding to pursue strategic project management training at Rice University, applying new skills to improve project outcomes.

Project Scientist

The Jackson Laboratory
10.2017 - 11.2021
  • Scientific Management/Collaborations: Directed and led six cross-functional teams, encompassing operations, business development managers, research and development scientists, technical information scientists, and finance and opportunity development managers to successfully design studies, create timelines and budgets, and execute complex, large-scale projects from approval to completion
  • Managed high-impact academic, government, and pharmaceutical projects globally, including those involving Jax mice and Clinical Research Services, as well as managing global model generation initiatives using CRISPR technology
  • Collaborated with operations, research and development scientists, and research teams to identify and strategic opportunities for scientific discovery, driving the development of improved techniques, and the creation of novel therapeutics
  • Delivered expert scientific input in the design of preclinical and translational research, including data interpretation, follow-up experiment planning, and troubleshooting, ensuring successful outcomes and advancing research objectives
  • Supported and executed strategies to strengthen existing collaborations and identify new partnership opportunities with domestic and international clients, driving the expansion of research initiatives and fostering global scientific advancements
  • Communications/Campaign Creation: Recipient of the IMPACT AWARD for exceptional client communication, demonstrating a strong ability to foster positive client relationships and deliver outstanding service
  • Designed and launched successful branding and marketing campaign for research models and services, creating impactful templates that enhanced brand visibility and engagement
  • Utilized advanced project management methodologies, maintaining regular communication with domestic and international clients through various channels, including email, phone, WebEx, MS Teams, and in-person meetings
  • Provided clear and concise project status updates, addressed client inquiries, resolved challenges, and defined scientific goals and deliverables for complex projects, ensuring alignment and successful outcomes
  • Developed globally standardized “in vivo” pharmacology study templates, facilitating seamless collaboration and communication between internal and external teams across the USA and Europe
  • Coordinated and organized a high-profile Jax seminar at the MD Anderson Cancer Center in 2018, showcasing thought leadership and driving knowledge-sharing within the scientific community
  • Budget/Regulatory Issues: Spearheaded the creation and management of comprehensive scientific project budgets for the oncology program, overseeing financial planning and allocation for projects totaling up to $10 million
  • Ensured strict adherence to all compliance and regulatory requirements, including federal, state, and institutional guidelines, maintaining the highest standards of regulatory integrity and operational excellence
  • Novel solutions/Quality Improvement/Research: Developed innovative processes and solutions to increase project success and strengthen cross-functional collaborations, driving overall program efficiency
  • Performed ongoing assessments of scientific and market opportunities, identifying portfolio gaps, and devising actionable solutions to enhance competitive positioning
  • Led the creation go-to-market strategies in partnership with the sales team, ensuring seamless market entry and maximizing revenue potential.

Postdoctoral Fellow - Immunology

University of Michigan
Ann Arbor, Michigan
01.2014 - 01.2017
  • Group project research leader for Rheumatology, Dental school, and Orthopedic Surgery departments Project: “A novel bone destruction inflammatory pathway and the association of Rheumatoid arthritis and periodontitis”
  • Spearheaded independent research on periodontal disease and rheumatoid arthritis, designing and executing experiments using shared epitope positive and negative mice, as well as collagen-induced arthritic models, contributing to key scientific insights
  • Designed animal protocols (eRAM) for nanoparticles drug delivery targeting HCC, prostate and breast cancer across for the entire laboratory, ensuring rigorous experiment design and compliance
  • Secured rapid approval of HCC IACUC protocols in less than one month
  • Wrote amendments for the protocols
  • DEA licensure for eRAM protocols
  • Mentored and trained a biomedical engineering graduate student in performing animal surgeries, conducting biological research experiments, and crafting detailed animal-protocols, fostering development into a skilled researcher
  • Wrote independent grants and assisted advisor in grant writing for 5 NIH and internal grants within 3 years
  • Three grants were funded from my scientific writing contributions (2 NIH and 1 internal grant)
  • Contributed to the scientific community by writing and publishing peer-reviewed 4 manuscripts, book chapters including Encyclopedia of Immunobiology, and detailed study reports, enhancing the visibility and impact of research findings
  • Partnered with the University of Florida’s College of Dentistry to provide specialized training in immuno-histochemistry techniques and immunology concepts, bridging the gap between biomedical research and clinical education.

Postdoctoral Fellow - Oncology

UT MD Anderson Cancer Center
Houston, Texas
11.2010 - 12.2013
  • Project: Radiological, Histological and Molecular Characterization of a Swine HCC Model and Isolation & Characterization of Liver Cancer Stem Cells
  • Pioneered the introduction of pre-clinical research capabilities to the laboratory
  • Independently designed and executed comprehensive research experiments across multiple high-impact projects, including: Development of a DENA-induced Gottingen minipig cirrhosis HCC model, advancing the understanding of hepatocellular carcinoma
  • Isolation and characterization of liver cancer stem cells and cancer, alongside the development of stem cell-based tumor models, driving innovative therapeutic approaches
  • Utilization of phage display peptide libraries in mice hepatocellular carcinoma (HCC) models to explore novel therapeutic targets
  • Implementation of nano-particles drug delivery in mice HCC models
  • Designed animal protocols, responded to amendments, and ensured compliance with IACUC standards, taking on the role of protocol manager
  • Served as a crucial liaison between the veterinary medicine department, pathologists, and research group, acting as the group leader for the four complex projects, ensuring seamless collaboration and project success
  • Mentored and guided undergraduate and graduate students, fostering the next generation of researchers
  • Established a key international collaboration with the University of Copenhagen, Denmark focusing on various aspects of the Gottingen mini pig project, driving global research initiatives
  • Collaborated on different projects with labs across multiple leading institutions, including MD Anderson, Rice University, and Methodist.

Senior Scientific Clinical Project Manager

Personalis Inc.
11.2021
  • Scientific Clinical Research Management/Collaborations: Spearheaded the advancement of multiple clinical programs in collaboration with top-tier pharmaceutical companies, driving innovations in treatment protocols and therapeutic development
  • Led the clinical development of advanced cancer genomics, facilitating the next generation of precision cancer therapies and diagnostics
  • Collaborated closely with operations, research and development scientists, and research teams to pinpoint strategic opportunities for scientific discovery, resulting in the development of enhanced research techniques and methodology
  • Provided expert scientific input across the design of clinical research studies, data interpretation, and follow-up experiment planning, ensuring the successful troubleshooting of issues and achievement of program objectives
  • Developed and implemented dashboards, tools and processes that streamlined processes for an innovation-driven product development team
  • Ensured that projects were delivered on time, within budget, and to the highest quality standards, in compliance with SOPs, GLP, CLIA, and relevant regulatory guidelines
  • Maintained ongoing communication with stakeholders, delivering timely project updates and ensuring alignment with strategic objectives
  • Anticipated and identified potential challenges, driving the team to develop proactive solutions and implement contingency plans, ensuring project continuity and success.

Education

Ph.D. in Radiation and Cancer Biology -

University of Rajasthan - Jaipur
Jaipur

Skills

  • Scientific Management/Collaborations
  • Administrative/Budget
  • Scientific Clinical Research Management/Collaborations
  • Communications/Campaign Creation
  • Budget/Regulatory Issues
  • Novel solutions/Quality Improvement/Research

Recognitioncertifications

  • Recognized as outstanding Alumni in Alumni Spotlight, 09/01/23, MD Anderson Cancer Center, Houston, TX
  • Leading Teams Leadership certification, 05/01/24, Leadership Institute, Houston, TX
  • Strategic Project Management Certification, 10/01/24, Susanne M. Glasscock School of Continuing Studies, Houston, TX

Publications

  • Spontaneous Destructive Periodontitis and Skeletal Bone Damage in Transgenic Mice Carrying a Human Shared Epitope-Coding HLA-DRB1 allele, Prashasnika Gehlot, S Volk, H Rios, K Jepsen and Joseph Holoshitz, RMD open, 2016
  • Periodontal bacterial colonization in synovial tissues exacerbates collagen-induced arthritis in B10.RIII mice, Sasanka Chukkapalli, Mercedes Rivera-Kweh, MS, Prashasnika Gehlot, PhD; Irina Velsko, PhD; Indraneel Bhattacharyya, BDS, DDS, MS; John Calise, BS; Minoru Satoh, MD, PhD; Edward Chan, PhD; Joseph Holoshitz, MD; Kesavalu Lakshmyya, Arthritis Research & Therapy, 2016
  • HLA (Human Leukocyte Antigen) and Autoimmunity, Prashasnika Gehlot and Joseph Holoshitz, Encyclopedia of Immunobiology, Volume 2, 2015
  • Detection of ALDH activity in rabbit vx2 liver tumor, Gehlot P
  • V Shukla, S Gupta and P E Makidon, J Transl Med, 2016
  • Enrichment of Gottingen minipigs - models of hepatocellular carcinoma, Prashasnika Gehlot, Newsletter published at Gottingen minipig research, 2013
  • Prevention of Radiation-induced Hepatic Damage in Swiss Albino Mice by Aloe vera Leaf Extract, Gehlot P., Soyal D and Goyal P K, Nuclear Technology & Radiation Protection, 2010
  • Inflammation and cancer: How friendly is the relationship for cancer patients?, Aggarwal BB and Gehlot P, Current opinion in pharmacology, 2009
  • Models for prevention and treatment of cancer: Problems vs promises, Aggarwal BB, Danda D, Gupta S and Gehlot P, Biochem Phrmacology, 2009

Volunteer Experience

  • Invited panel leader and invited speaker for career development, 09/01/23, Baylor College of Medicine
  • Citizen Science Program Faculty, 2017, Bard College, Albany, NY, Mentored and trained students on various lab techniques. Led one-on-one and group discussions with students in the classroom.
  • Liaison for the organizing committee Board member, 05/01/15, University of Michigan, National conference entitled 'Future of Bioscience Graduate and Postdoctoral Training'
  • Vice President and Co-Chair for Career Development, 07/01/14 - 12/31/16, Association of Women in Science (AWIS), Served as a representative of women postdocs in the AWIS team. Wrote articles for AWIS magazine under leadership to promote professional development for STEM postdocs.
  • Chair & Board Member, 03/01/14 - 12/31/15, Postdoctoral Association, University of Michigan, Attended postdoctoral advisory committee (PDAC) meetings and facilitated collaborative initiatives such as the postdoctoral science symposium at MDA, science fair, and coffee networking for international postdoctoral fellows. Functioned as the liaison for the office of Trainee and Alumni Affairs (TAA) between faculty and the community of over 1500 postdoctoral fellows for postdoctoral-related issues. Organized the speakers and sessions according to the NIH grant writing workshops for postdocs.
  • Liaison, Trainee & Alumni Affairs and Postdoctoral Chair, Responsible Conduct of Research (RCR), 10/01/11 - 12/31/13, The University of Texas MD Anderson Cancer Center, Houston, TX, Functioned as the liaison for Trainee and Alumni Affairs (TAA) between TAA and the community of over 600 postdoctoral fellows for postdoctoral-related issues. RCR committee: organized the development of RCR training with TAA from reviewing policies to speaker selection and event hosting for training. Reviewed and rated Trainee Excellence awards. Facilitated collaborative initiatives for the annual postdoctoral science symposium at MDA and science fair and coffee networking events for International postdocs. Served on the Mentor Award Selection Committee and helped plan and execute the ceremony for TAA.

Timeline

Director, Research Planning & Development

MD Anderson Cancer Center
01.2023 - Current

Senior Scientific Clinical Project Manager

Personalis Inc.
11.2021

Project Scientist

The Jackson Laboratory
10.2017 - 11.2021

Postdoctoral Fellow - Immunology

University of Michigan
01.2014 - 01.2017

Postdoctoral Fellow - Oncology

UT MD Anderson Cancer Center
11.2010 - 12.2013

Ph.D. in Radiation and Cancer Biology -

University of Rajasthan - Jaipur
Prashasnika Gehlot