Samuel Kwakye Ayeh. MD, MPH.

• Board-certified internal medicine physician with clinical practice and research expertise, dedicated to providing the highest quality care to my patients.
• A research career path with 2 years of pre-clinical research as a postdoctoral fellow at the Johns Hopkins School of Medicine.
• A Master of Public Health degree with a Major in Epidemiology & Biostatistical Methods for Public Health & Clinical Research from the Johns Hopkins School of Public Health

• Certificate In Pharmacoepidemiology And Drug Safety- May, 2019
  Johns Hopkins University Bloomberg School Of Public Health - Baltimore, MD

• Medical Practice License(Ghana)- 2012 till date

     Medical and Dental Council, Ghana

• Central line placement
• Arterial line placement

Identifying several Immune-Modulator Drugs That Target Lipid Formation in Foam Cells.

• Identify immune based drugs that could be used as an adjunctive therapy in Tuberculosis treatment to shorten the duration of TB treatment.

Therapeutic DNA Vaccine Targeting A Mycobacterium Stringent Response Pathway Protein Called REL Protein.

• Generate a therapeutic Vaccine that will serve as an adjunct to the current treatment for Tuberculosis to shorten the Duration of treatment.

Peer Reviewed Journal Articles/Abstracts

• James T. Gordy · Kun Luo · Aakanksha Kapoor · Emily S. Kim · Samuel K. Ayeh · Petros C. Karakousis · Richard B. Markham. Treatment with an immature dendritic cell-targeting vaccine supplemented with Interferon-gamma and an inhibitor of DNA methylation markedly enhances survival in a murine melanoma model. Springer link. 2020, Jan; 2020(69): 569-580. Cited in PubMed; PMID: 31980915. Pub Status: Published

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• Enoch J Abbey, Banda A. A Khalifa, Modupe O. Oduwole, Samuel K. Ayeh, Richard D. Nudotor, Emmanuella L. Salia, Oluwatobi Lasisi, Seth Bennett, Hasiya E. Yusuf, Allison L. Agwu, Petros C. Karakousis. ( October 7, 2020 ). The Global Health Security Index is not predictive of coronavirus pandemic responses among Organization for Economic Cooperation and Development countries. https://doi.org/10.1371/journal.pone.0239398, Pub Status: Published.

• Vignesh Chidambaram, Nyan Lynn Tun, Waqas Haque, Marie Gilbert Majella, Ranjith Kumar Sivakumar, Amudha Kumar, Angela Ting-Wei Hsu, Izza Ishak, Aqsha Nur, Samuel K. Ayeh, Emmanuella Salia, Ahsan Zil-E-Ali, Muhammad Saeed, Ayu Sarena, Bhavna Seth, Muzzammil A. ( November 18, 2020 ). Factors Associated with Disease Severity and Mortality among Patients with Coronavirus Disease 2019: A Systematic Review and Meta-Analysis. https://doi.org/10.1371/journal.pone.0241541, Pub Status: Published.

• Richard Nudotor, Hasiya Yusuf, Owulatobi Lasisi, Emmanuella Salia, Banda Khalifa, Enoch Abbey, Modupe Oduwole, Samuel K Ayeh, Obeng Appiafo, Joseph Canner, Ann Scheimann & Kimberley E. Steele. A Retrospective Analysis of the Impact of Bariatric Surgery on the Management of Chronic Migraine. Obesity Surgery( 11 February 2021 ). https://doi.org/10.1007/s11695-020-05204-w, Pub Status: Published

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• Nathan P Crilly, Samuel K Ayeh, Petros C Karakousis The new frontier of host-directed therapies for Mycobacterium avium complex . Front Immunol. ( 2021 Jan 22 ). doi: 10.3389/fimmu.2020.623119 Pub Status: Published

• Zhou, L., Ayeh, S.K., Chidambaram, V. et al. Modes of transmission of SARS-CoV-2 and evidence for preventive behavioral interventions. BMC Infect Dis 21, 496 (2021). https://doi.org/10.1186/s12879-021-06222-4

• Ayeh SK, Abbey EJ, Khalifa BAA, Nudotor RD, Osei AD, Chidambaram V, et al. (2021) Statins use and COVID-19 outcomes in hospitalized patients. PLoS ONE 16(9): e0256899. https://doi.org/10.1371/journal.pone.0256899

• Vignesh Chidambaram, Nyan Lynn Tun, Marie Gilbert Majella, Jennie Ruelas Castillo, Samuel K Ayeh, Amudha Kumar, Pranita Neupane, Ranjith Kumar Sivakumar, Ei Phyo Win, Enoch J Abbey, Siqing Wang, Alyssa Zimmerman, Jaime Blanck, Akshay Gupte, Jann-Yuan Wang, Petros C Karakousis, Male Sex Is Associated With Worse Microbiological and Clinical Outcomes Following Tuberculosis Treatment: A Retrospective Cohort Study, a Systematic Review of the Literature, and Meta-analysis, Clinical Infectious Diseases, Volume 73, Issue 9, 1 November 2021, Pages 1580–1588, https://doi.org/10.1093/cid/ciab527

• Chidambaram V, Zhou L, Ruelas Castillo J, et al. Higher Serum Cholesterol Levels Are Associated With Reduced Systemic Inflammation and Mortality During Tuberculosis Treatment Independent of Body Mass Index. Front Cardiovasc Med. 2021;8:696517. Published 2021 Jun 22. doi:10.3389/fcvm.2021.696517

• An intranasal stringent response vaccine targeting dendritic cells as a novel adjunctive therapy against tuberculosis Styliani Karanika, James T. Gordy, Pranita Neupane, Theodoros Karantanos, Jennie Ruelas Castillo, Darla Quijada, Kaitlyn Comstock, Avinaash Kaur Sandhu, Yinan Hui, Samuel K. Ayeh, Rokeya Tasneen, Stefanie Krug, Carina Danchik, Tianyin Wang, Courtney Schill, Rirchard B. Markham, Petros C. Karakousis bioRxiv 2022.04.19.488816; doi: https://doi.org/10.1101/2022.04.19.488816

• IFNα and 5-Aza-2’-deoxycytidine combined with a dendritic-cell targeting DNA vaccine alter tumor immune cell infiltration in the B16F10 melanoma model. Gordy JT, Sandhu AK, Fessler K, Luo K, Kapoor AR, Ayeh SK, Hui Y, Schill C, Chen F, Wang T, Karanika S, Sunshine JC, Karakousis PC, Markham RB. IFNα and 5-Aza-2'-deoxycytidine combined with a dendritic-cell targeting DNA vaccine alter tumor immune cell infiltration in the B16F10 melanoma model. Front Immunol. 2023 Jan 19;13:1074644. doi: 10.3389/fimmu.2022.1074644. PMID: 36741387; PMCID:PMC9892704.

• Best worker (Physicians and Physician Assistants Category) at the St. Gregory Catholic Hospital. Ghana- 01/2016 - 12/2016
• A full term(One-time) Merit-Based Scholarship from the Johns Hopkins Bloomberg School of Public Health- 2018-2019 Academic year

Head of Zero Maternal mortality Team and Maternal Mortality Audit Team at St Gregory Catholic Hospital, Buduburam, Ghana

01/2015-12/2017

• The team's role is to review every case of maternal death to address issues underlying each maternal death at the hospital,

Head of Project Five -Alive Team at St Gregory Catholic Hospital,Ghana.

01/2016-12/2016

• To Review every under -five death and come up with intervention to address underlying causes.

Addressing Hypertension Control in Africa (ADINCHRA) study-2019

• My collaboration with clinical investigators at the Johns Hopkins School of Nursing on the Addressing Hypertension Control in Africa (ADINCHRA) study, has led to production of a medical education video to be used in training health professionals in Ghana and Africa on hypertension management.

Denver health Community Outreach- 05/ 2019

• Volunteer Activity involving Denver Health and Wish for wheels where we assembled about 100 bicycles and gave these new bicycles
  to the less-privileged children in Denver community,Colorado.
• Together with the social worker for Denver Health(Pena Clinic), Sophia Chavez, we visited a Spanish Community and helped with food stuff distribution.

Johns Hopkins Bloomberg School Of Public Health International Students day-06/24/2019

• As a facilitator for the Johns Hopkins Bloomberg School Of Public Health International Students day, I led a small of group of students through a round-table discussion on how to maximize their MPH experience and took them on a school-wide tour.

• Ghana Medical Association-2012 till date

• Anita Tamara

Associate Chair of Medicine

Associate Program Director, Medstar Health Internal Medicine Residency Program (MHIM)
Medical Director, Primary Care Center at Medstar Franklin Medical Center

Assistant Professor, Division of General Internal Medicine/Department of Medicine, Georgetown University Medical Center

Email: Anita.Tammara@medstar.net

Phone:240-481-8087

• Chardon-Borrero Madai

Medstar Primary Care Clinic Attending

Email: madai.chardon-borrero@medstar.net

Phone: 443-691-0501

• Gregory Nizialek

Program Director

Medstar Health Internal Medicine Residency Program

201 East University Parkway

Baltimore, Maryland, 21218 

Email: gregory.a.nizialek@medstar.net

Phon

• Https://www.jhsph.edu/research/centers-and-institutes/center-for-drug-safety-and-effectiveness/training/
• (https://www.youtube.com/watch?v=SNyhoG__ciU)