Seairah Demers

The Global Quality Control Technical Services team is responsible for the analytical method lifecycle including transfer and validation, stability, reference standard and critical reagent, product specification, equipment and computer systems validation support, and pharmacopoeia program. These activities are all performed in accordance with cGMP guidelines and are supported by departmental and inter-departmental policies and standard operating procedures.

• Worked under general guidance to support critical material program, including stock inventory management, initial qualification and annual requalification
• Owned various quality records, such as Change Controls, Deviations and CAPAs
• Wrote protocols and reports, and facilitated in comment reconciliation
• Assisted with data trending and aid in compilation of trend reports
• Established, revised, reviewed and maintained procedures (including protocol and technical report).
• Completed all training and documentation in accordance with current Good Manufacturing Practices (cGMP)
• Assisted QC leads in support of computer systems lifecycle, including validation, operation, and maintenance
• Data Mined for QC raw data results
• Used SmartSheets to record data and calculate expiration dates of drugs, drug stability, along with various other calculations
• Used JMP Statistical Software to analyze data and determine trends from QC test results
• Participated in Six Sigma Certification Training

As a part of my research position, I evaluated the effects of mechanical stimuli on cell behavior in engineered tissues. I used C2C12 cells (myoblasts) and human mesenchymal stem cells to look at how mechanical stimuli impact muscle tissue function. Individual tasks included:

• Basic cell culture (feeding, passing, counting, microscopic evaluation)
• Creation of GelMA hydrogels (weighing, calculating, UV exposure)
• Mechanical evaluation of hydrogels (compression testing w/Instron)
• Analysis of mechanical testing (using Matlab routine to analyze stress-strain data)
• Creation/culturing of cell-laden hydrogels
• Microscopic evaluation of cell-laden hydrogels to assess tissue formation/function
• Fabrication of GelMA precursor from gelatin (reacting gelatin with methacrylic anhydride to incorporate methacrylate groups onto gelatin, also involves dialysis and lyophilization.

The Orientation Leader (OL) program is a nine-month student leadership opportunity; the commitment consists of consecutive spring and fall semesters, including the summer and fall orientation sessions. Things completed:

• Enhanced student orientation experience by organizing interactive activities and icebreakers.
• Ensured student success by providing resources, guidance, and support throughout the orientation process.
• Developed strong connections with students through active listening and empathetic communication skills.
• Demonstrated excellent interpersonal skills by fostering a sense of community and camaraderie among new students.

An outdoor adventure company focused on bringing adventure to those with disabilities. There I volunteer as a rock climbing instructor teaching participants skills such as outdoor climbing safety, belaying, knot tying, anchor building, rappelling, rock climbing rescue maneuvers, rock climbing history, geology of rock faces, as well as rock climbing techniques. In addition, I also teach mountaineering skills such as search and rescue skills, wilderness first aid, land navigation, survival skills, as well as lead groups of participants on hikes. My acomplishments:

• Improved safety standards by conducting thorough equipment inspections before each climbing session.
• Contributed to the growth of the rock climbing program by actively seeking feedback from clients to continually refine instructional methods and practices.
• Collaborated with colleagues on creating new instructional courses for advanced climbers looking to expand their skillsets further.
• Evaluated clients' progress regularly and adjusted instructional strategies accordingly to help them achieve their personal climbing goals effectively.

• Supported staff members in their daily tasks, reducing workload burden and allowing for increased focus on higher-priority assignments.
• Gained valuable experience working within a specific industry, applying learned concepts directly into relevant work situations.
• Sorted and organized files, spreadsheets, and reports.
• Gained hands-on experience in various software programs, increasing proficiency and expanding technical skill set.