Shankaran Kothandaraman
Plain City
Summary
Performance-driven scientist with extensive experience in leading complex R&D projects within the pharmaceutical sector. Proficient in organic, medicinal, heterocyclic, peptides, and biological chemistry, alongside advanced laboratory techniques. Proven ability to develop high-performing technical teams and manage competing project flows in dynamic environments. Expertise in data modeling, analysis, and interpretation, with a strong focus on aligning research findings with business strategies.
Overview
35
35
years of professional experience
Work History
Senior Scientist
Moderna Therapeutics
Cambridge
08.2021 - 03.2025
- Maintained cutting-edge knowledge of Nucleotide chemistry thorough literature review.
Resolved complex issues within experimental setups, achieving successful outcomes amid challenges.
Enhanced team performance by mentoring fellow chemists and sharing best practices.
Cultivated collaborative partnerships with other research group members to optimize resources.
Research Chemist
Ohio State University
Columbus
09.2009 - 05.2020
- Led design of diagnostic and therapeutic peptides and small molecules targeting breast, head and neck, and prostate cancers.
Prepared heterocyclic analogs for collaborative Alzheimer's disease research focusing on Abeta plaque.
Proposed chemical synthesis of peptide and non-peptide molecules for radioactive ligand preparation.
Discovered cell penetrating peptide molecule targeting head and neck cancer cells; developed structure-activity relationship.
Conjugated cell penetrating peptide to NIR probes to enhance optical surgical navigation for tumor detection.
Senior Research Fellow
Merck and Co., Inc.
Rahway
07.1990 - 10.2008
- Defined project scope and design for lead discovery, target validation, and optimization initiatives.
Tracked milestones and analyzed data while maintaining communication through oral and written reports.
Collaborated with 20+ team members to enhance research on inflammation, focusing on enzyme inhibitors and receptor antagonists.
Engaged team members to foster innovation and mitigate research drawbacks using key literature.
Drove chemistry advancements in anemia, obesity, pain management, and arteriosclerosis.
Coordinated with cross-functional teams to prepare heterocyclic analogs targeting HIV cellular penetration.
Received multiple awards for significant contributions to lead discovery and optimization projects.
Managed comprehensive communication channels to ensure project alignment and stakeholder engagement.
Education
Ph.D. - Organic Chemistry
University of Poona
PuneSkills
- Team collaboration
Comprehensive documentation
Laboratory management
Data analysis
Clear communication
Project timeline management
Attention to detail
Stakeholder engagement
Creative problem-solving
Logical evaluation
Accomplishments
- Senior and Junior Research Fellowship of Government of India., Multiple awards from Merck for contribution to various programs.
Languages
English
Professional
References
References available upon request.
Timeline
Senior Scientist
Moderna Therapeutics
08.2021 - 03.2025
Research Chemist
Ohio State University
09.2009 - 05.2020
Senior Research Fellow
Merck and Co., Inc.
07.1990 - 10.2008
Ph.D. - Organic Chemistry
University of Poona
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