Summary
Overview
Work History
Education
Skills
Websites
Accomplishments
Leadership Experience
Presentations
Affiliations
Office Address
Office
Correspondence
Current Grant Support
Completed Grant Support
Grant Participation
Proposals In Preparation
Unfunded Proposals
Underrepresented Minority Student Mentoring
Teaching
Service Experience
Bibliography
Research
Personal Information
Awards
Timeline
Generic

Simone Marsha-Lee Smith

Greensboro,NC

Summary

Skilled Researcher enthusiastic about supporting advancements in cell biology. Passionate about increasing knowledge to drive growth and needed improvements. Ready to apply knowledge and 23 years of experience in research.

Overview

20
20
years of professional experience

Work History

Assistant Professor of Anatomy and Physiology

North Carolina A&T State University

Senior Research Fellow in Bone and Extracellular Matrix

National Institute of Child Health and Human Development
01.2013 - 01.2016
  • Supervisor: Joan C
  • Marini, M.D., PhD

Research Associate in Molecular Pharmacology & Physiology

Morsani College of Medicine at University of South Florida (USF)
01.2012 - 01.2013
  • Supervisor: David E
  • Birk, PhD

Postdoctoral Research Fellow in Pathology & Cell Biology

Morsani College of Medicine at USF
01.2007 - 01.2012
  • Supervisor: David E
  • Birk, PhD

Graduate Research Assistant in Biochemistry & Molecular Biology

USF College of Medicine
01.2000 - 01.2007
  • Supervisor: John R
  • Hassell, PhD
  • Dissertation title: The proteoglycan perlecan regulates long bone growth through interactions with developmental proteins in the growth plate.

Graduate Research Assistant

University of Florida College of Medicine Interdisciplinary PhD Program
01.1998 - 01.1999
  • Research conducted with: William Hauswirth, PhD; Margaret Wallace, PhD; William Kem, PhD

Undergraduate Honors Research Fellow in Biochemistry & Molecular Biology

USF College of Medicine and the James A. Haley VA Hospital
01.1996 - 01.1998
  • Supervisor: William R
  • Gower, PhD
  • Honors Thesis Title: Expression of the gastrointestinal regulatory peptides, i.e
  • Atrial natriuretic peptides, and their receptors in a mouse model of congestive heart failure.

Education

Doctor of Philosophy - Medical Science, Biochemistry & Molecular Biology

Morsani College of Medicine at the University of South Florida (USF)
01.2007

Bachelor of Science - Biology

Judy Genshaft Honors College at USF
01.1998

Skills

  • Mentoring students
  • Lecturing
  • Classroom Management
  • Faculty Collaboration
  • Scientific Writing
  • Data Analysis
  • Laboratory techniques
  • Research program planning
  • Research methods
  • Results interpretation
  • Statistical modeling
  • Experiment Design
  • Qualitative Research
  • Research grants
  • Quantitative Research
  • Experimental design
  • Training and mentoring
  • Analytical Thinking
  • Microsoft Excel proficiency
  • Report Writing
  • Self-Driven and Motivated
  • Laboratory Studies
  • Effective Multitasking
  • Advanced Research Techniques
  • Data Collection
  • Scientific Method
  • Grant Writing
  • Research ethics knowledge
  • Systematic literature review
  • Data management planning

Accomplishments

  • Achieved [Result] by introducing [Software] for [Type] tasks.
  • Documented and resolved [Issue] which led to [Results].
  • Achieved [Result] through effectively helping with [Task].
  • Collaborated with team of [Number] in the development of [Project name].
  • Supervised team of [Number] staff members.
  • Used Microsoft Excel to develop inventory tracking spreadsheets.
  • Achieved [Result] by completing [Task] with accuracy and efficiency.

Leadership Experience

Faculty lead in redesign of BIOL210 (Writing in Biology), NC A&T

Presentations

  • Analysis of phenolic compounds in Bryophyllum Pinnatum leaf using different organic solvents, Annual Biomedical Research Conference for Minority Students (ABRCMS), 11/2023, Phoenix, AZ
  • Unraveling the Skin Aging Mosaic, NC A&T Scientific Research Preparatory Program Closing Session, 07/2023
  • Molecular Biomarker Discovery in Aging and Injury Repair of Skin, NC A&T Undergraduate Research and Creativity Symposium, Spring 2021
  • Molecular Biomarker Discovery in Aging and Injury Repair of Skin, ABRCMS, 11/2018, Indianapolis, IN
  • CRTAP, the causative protein in type VII OI, is an ER membrane-tethered molecule, 2015 Annual Meeting of the ASBMR (American Society for Bone and Mineral Research), 10/2015, Seattle, WA
  • Is CRTAP, the causative protein in type VII OI, an ER membrane-tethered molecule?, 12th International Conference on Osteogenesis Imperfecta, 10/2014, Wilmington, DE
  • Cell surface tethers of the regulatory collagen type V on the tendon fibroblast, Orthopaedic Research Society 58th Annual Meeting, 02/2012, San Francisco, CA
  • Pericellular proteins of the developing mouse tendon: a proteomic analysis, American Society for Matrix Biology Biennial Meeting, 10/2010, Charleston, SC
  • The tendon fibroblast surfaceome in collagen fibrillogenesis, Orthopaedic Research Society 56th Annual Meeting, 03/2010, New Orleans, LA
  • Interactions in the tenocyte surfaceome regulate collagen fibrillogenesis, Gordon Research Conference on Collagen, 07/2009, New London, NH
  • Binding partners of the proteoglycan perlecan in developing growth plate, American Society for Matrix Biology Biennial Meeting, 10/2004, San Diego, CA
  • The proteoglycan perlecan in the developing growth plate, Gordon Research Conference on Proteoglycans, 07/2004, Andover, NH

Affiliations

  • American Society for Cell Biology (2017-present)
  • American Society for Bone and Mineral Research (2014-present)
  • American Association for the Advancement of Science (2011-present)
  • Orthopaedic Research Society (2010-2013)
  • International Society for Matrix Biology (2008-2013)
  • American Society for Matrix Biology (2002-2007)
  • Phi Kappa Phi International Honor Society (1998-present)

Office Address

Barnes Hall 104, 1601 E. Market St, Greensboro, NC, 27411

Office

Barnes Hall, G19

Correspondence

(336) 285-2207, smsmith8@ncat.edu

Current Grant Support

  • Scientific Research Preparatory Program (STEM Ed contract), National Institutes of Health (NIH) NINDS, 6480155, Co-Coordinator, $249,949.00, 09/2022 - 09/2025
  • Broadening Participation Research: Strategic Application of Science Capital to Increase African-American Students' Motivation, Retention and Persistence in STEM at an HBCU, National Science Foundation (NSF), 1912585, Co-PI, Checo Rorie, Karen Jackson, $349,999.00, 06/2019 - 05/2025

Completed Grant Support

  • Isolation and Characterization of Protein Complexes Involved in Wound Healing, NC A&T TraCS Office Interdisciplinary Team Science Award (ITSA), 881, PI, Robert Newman, Jenora Waterman, Kristen Rhinehardt, $20,000.00, 01/2021 - 06/2021
  • Molecular signatures of chronically impaired wounds in diabetes and aging, Summer Research Seed Funding Program, PI, $5,000.00, 06/2019 - 08/2019
  • Regulation of tendon extracellular matrix assembly by the fibroblast surfaceome, Ruth L. Kirschstein Postdoctoral National Research Service Award (NRSA #F32AR056937), National Institute of Arthritis and Musculoskeletal and Skin Diseases/NIH, PI, David Birk, University of South FL, $149,898.00, 100%, 08/2009 - 07/2012

Grant Participation

Bridges to Doctorate - Bioinformatics and Biomedical Bridges Between NCAT and UNC-CH (STEM Ed), National Institutes of Health (NIH), 190025, Participating Faculty, Patrick Martin, N. Bhattarai, M. Bikdash, G. Byrd, C. Doss, K. Flurchick, G. Goins, J. Han, S. Harrison, L. Jeffers-Francis, D. KC, M. McCullough, S. Mills, R. Newman, E. Ongeri, C. Rorie, M. Thomas, J. Waterman, $1,463,762.88, 01/2018 - 01/2023

Proposals In Preparation

  • Identifying the wound healing properties of bioactive compounds in a Leaf of Life (Kalanchoe pinnata, bryophyllum pinnatum) extract using a full-thickness animal-free skin injury model, NIH Exploratory/Developmental Research Grant (R21), 11/16/2024, PI, 08/2025 - 07/2027
  • Identifying additive wound healing effects of the Integrin-Fibronectin repertoire in a full-thickness animal-free skin injury model, NIH Exploratory/Developmental Research Grant (R21), 11/16/2024, PI, 08/2025 - 07/2027

Unfunded Proposals

  • Isolation and Characterization of Protein Complexes Involved in Wound Healing, North Carolina Diabetes Research Center (NCDRC) Pilot Grant Proposal, 10/19/2022, PI, $50,000.00, 04/2023 - 03/2024
  • Molecular Biomarker Discovery in Injury Repair of Skin, UNC-CH North Carolina Translational and Clinical Sciences (NC TraCS) Institute Proposal #19-0132, PI, $50,000.00, 02/2019 - 01/2020
  • Molecular Signatures of Chronically-Impaired wounds in diabetes and aging, NC TraCS Career Development Scholars Program, 03/2020, PI
  • Molecular Biomarker Discovery in Aging and in Injury Repair of Skin, National Institutes of Health (NIGMS/NIH) Support of Competitive Research (SCORE) Pilot Project Award (SC2), 18-0475, Principal Investigator, David E. Birk, University of South FL, $367,341.12, 01/2018 - 01/2021
  • Scar Tactics: Molecular Biomarker Discovery in Aging and Injury Repair of Flexor Tendon and Skin, Historically Black Colleges and Universities Undergraduate Program (HBCU-UP) Research Initiation Awards (RIA), 16-538, PI

Underrepresented Minority Student Mentoring

  • 08/2023, Christen Daniel (NC A&T Biology B.S. class of 2025), Kennedy Williams (class of 2026)
  • 08/2021, Jakara Jordan (NC A&T Biology M.S. class of 2024), Korwen Mouzon (NC A&T Biology B.S. class of 2023, 2-year post-bac scholar at ORISE)
  • 09/2021, 11/2021, Caio Silva (NC A&T Biology M.S. 2023 student), Withdrew for health and professional reasons
  • 06/2021, Jayla Watson (GTCC Graduate and Intern in the LSAMP B2B Program, current NC A&T student)
  • 08/2019, 05/2022, Nia Hammett (NC A&T Biology B.S. class of 2022, finalist for EBONY's 2022 HBCU STEM QUEEN, Duke University Master of Biomedical Sciences Program class of 2023, matriculant to ECU Brody School of Medicine class of 2028)
  • 08/2019, 05/2021, Aliyah Anderson (NC A&T Biology B.S. class of 2021, current Ph.D student at Morehouse School of Medicine, Atlanta, GA, class of 2026)
  • 06/2019, Jayla Watson (GTCC Intern in the LSAMP B2B Program, current NC A&T student)
  • 06/2018, Sheliah Harris (GTCC Graduate and Intern in the LSAMP B2B Program, NC A&T State Biology B.S. class of 2021, current High school Chemistry teacher, New Garden Friends School, Greensboro, NC)
  • 08/2017, 05/2020, Mariah McKinnon (NC A&T Biomedical Engineering B.S. class of 2020, current Onsite Endoscopic Specialist II at KARL-STORZ Endoscopy-America, Inc., El Segundo, CA)
  • 08/2017, 05/2020, Trevor Surratt (NC A&T Biomedical Engineering B.S. class of 2020, inaugural (2021) class of Corning Scholars and Fellows at NC A&T, current SMDP MedTech scholar at NC A&T)
  • 06/2017, Paul Nyarko (GTCC Graduate and Intern in the LSAMP B2B Program, current Laboratory Technician at City of Wilson, NC Water Reclamation Facility)

Teaching

  • BIOL205, Biology Orientation II, Freshmen and Sophomores, NC A&T State University, 01/2024
  • BIOL789/792, Biological Seminar I, Master's students in Biology, NC A&T State University, 01/2021
  • AST992, Doctoral Seminar Bioscience, Graduate students in Bioscience concentration of Applied Science and Technology Ph.D. program, NC A&T State University, 01/2021
  • BIOL105, Biology Orientation, Freshmen, NC A&T State University, 08/2018
  • BIOL210, Writing in Biology, Sophomores/Juniors, NC A&T State University, 08/2017
  • BIOL350, Human Anatomy & Physiology, Juniors/Seniors, NC A&T State University, 08/2017
  • BIOL450, Human Anatomy & Physiology, Juniors/Seniors, NC A&T State University, 08/2016
  • BIOL355, Principles of Biology of Bone and Other Connective Tissues, Graduate School at NIH, FAES (Foundation for Advanced Education in the Sciences), 08/2015

Service Experience

  • Seminar and Publicity Committee, Biology, NC A&T
  • Judge, NC A&T Undergraduate Spring Research Symposium, 04/2023
  • College of Science and Technology faculty senate alternate, NC A&T
  • Search Committee, Biology Department Associate Professor (Cancer), Biology, NC A&T, 06/2022
  • Dissertation Graduate Faculty Representative, Marki Johnson, Leadership Studies and Adult Education, NC A&T, Ph.D class of 2023, A Critical Study of College Administrator Responses to Institutional Policies & Practices that Support Students on the Spectrum, 08/2019, 05/2023
  • Dissertation Committee Member, Shilpi Bhatia, Applied Science and Technology, NC A&T, Ph.D, Role for BK polyomavirus (BKyV) in p53-mediated prostate cancer in African vs Caucasian-American patients, 08/2019, 05/2023
  • Dissertation Committee Member, Laquaundra Hampton, Applied Science and Technology, NC A&T, Ph.D class of 2023, Impact of Redox Modification on MAP Kinase substrate Selection, 08/2020, 05/2023
  • NSF Graduate Research Fellowship Program (GRFP) grant editor/reviewer, 01/2021, 01/2022
  • Thesis Committee Member, Naudia M. Gay, Biology, NC A&T, M.S. Bridges to Doctorate class of 2020, The Impact of Oxidation on PKA Binding Interactions with PKI, 08/2020, 05/2022
  • Thesis Committee Member, Aldeisha D. Smith, Biology, NC A&T, M.S. class of 2020, Potential for the Use of Silver and Bacteriophage Combination Therapy as an Escherichia coli Antimicrobial, 08/2018, 05/2020
  • NC A&T College of Science and Technology Undergraduate Research Council, NC A&T, 08/2019, 05/2020
  • Search Committees, Biology department Assistant/Associate Professor (Neuroscience), Biology department Non-Tenure Track Teaching Assistant Professor position 1, Biology department Non-Tenure Track Teaching Assistant Professor position 2, Biology, NC A&T, Spring 2019
  • MS Thesis Committee member, Laquaundra Hampton, Impact of Redox Modification on p38 Global Substrate Selection, 03/2019, 12/2019
  • MS Thesis Committee member, Jaime Ingram, Relation of Hydrogen Peroxide to Health Awareness and Behaviors, 11/2018, 12/2018
  • Judge, Annual Biomedical Research Conference for Minority Students (ABRCMS), 11/2018
  • Judge, NC A&T Undergraduate Research Symposium, 11/2017
  • Chair, Seminar and Publicity Committee, Biology, NC A&T, 08/2017
  • Co-chair, Scholarship Committee, Biology, NC A&T
  • Ad hoc Reviewer, Experimental Eye Research (2013), Gene (2015), BMC Musculoskeletal Disorders (2016), Connective Tissue Research (2017, 2020, 2023)
  • Grant Writing and Editing, NICHD MGL (Molecular Genomics Lab) subsidized funding application, NIH Division of Intramural Research (DIR) Director's Award application, 2015, 2014

Bibliography

  • Science Capital Survey Preliminary Results from 5 years of data collection at a large HBCU, Jackson KT, Smith SM, Smith AD, Patterson JW, White AM, Rorie CJ, Preliminary data analysis and article framing are complete for a summer/fall 2024 submission
  • Teaching Point of Care Ultrasound (POCUS) to Undergraduate Students at a public HBCU: Rationale, Design, and Implementation, Deacon IF, Smith SM, Chen Y, Sarwal A, Samuel RE, All data collected; manuscript in preparation for spring/summer 2024 submission
  • Considering Student Science Capital in Biology Programs at HBCUs: Developing Faculty STEM Leaders to Support Broadening Participation in Research, Jackson KT, Smith SM, Smith AD, Patterson JW, White AM, Rorie CJ, All data collected; manuscript in preparation for spring/summer 2024 submission
  • Unveiling Hidden Science Capital in Student-directed projects from a Scientific Writing Course, Smith SM, Smith AD, Adjei-Fremah S., Rorie CJ, Jackson KT, Reviewed favorably but we withdrew paper; preparing for spring 2024 submission to more appropriate journal
  • Elucidating the age-specific proteomic profiles of skin extracellular matrix to understand their orchestration of regenerative wound healing, Mouzon K, Hammett NS, Anderson AD, Mackinnon ME, Surratt TT, Smith, SM, Manuscript prepared for submission in spring 2024
  • CRTAP, the causative protein in type VII OI, partially localizes to the ER membrane, Smith SM, Marini JC, Manuscript completed, 2016
  • Osteogenesis Imperfecta, Marini JC, Endotext 2015. In: De Groot, Beck-Peccoz et. al., (Editors). Endotext [Internet]. South Dartmouth (MA): MDText.com, Inc.; 2000-. 2015 Apr 22. PMID: 25905334
  • Osteogenesis Imperfecta due to mutations in non-collagenous genes: Lessons in bone biology, Marini JC, Reich A, Smith SM, Curr Opin Pediatr. 2014 Aug;26(4):500-7. doi: 10.1097/MOP.0000000000000117
  • Collagen V localizes to pericellular sites during tendon collagen fibrillogenesis, Smith SM, Zhang G, Birk DE, Matrix Biol. 2013 Aug 15. pii: S0945-053X(13)00119-4. doi: 10.1016/j.matbio.2013.08.003. [Epub ahead of print]
  • Pericellular proteins of the developing mouse tendon: a proteomic analysis, Smith SM, Thomas CE, Birk DE, Connect Tissue Res. 2012;53(1):2-132011. 53(1): 2-13. Epub Aug 18, 2011
  • Regulation of collagen fibril nucleation and initial fibril assembly involves coordinate interactions with collagens V and XI in developing tendon, Wenstrup RJ, Smith SM, Florer JB, Zhang G, Beason DP, Seegmiller RE, Soslowsky LJ, Birk DE, J Biol Chem. 2011 Jun 10;286(23):20455-65. Epub 2011 Apr 5
  • Focus on Molecules: Collagens V and XI, Smith SM, Birk DE, Exp Eye Res. Epub 2010 Aug 10
  • Perlecan (HSPG2), Smith S, Hassell JR, Exp Eye Res. 2006 Sep;83(3):471-2. Epub 2006 Mar 23
  • Modulation of FGF-2 binding to chondrocytes from the developing growth plate by perlecan

Research

  • Senior Research Fellow in Bone and Extracellular Matrix, National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD, Joan C. Marini, M.D., PhD, 2013-01-01, 2016-12-31
  • Research Associate in Molecular Pharmacology & Physiology, Morsani College of Medicine at University of South Florida (USF), Tampa, FL, David E. Birk, PhD, 2012-01-01, 2013-12-31
  • Postdoctoral Research Fellow in Pathology & Cell Biology, Morsani College of Medicine at USF, Tampa, FL, David E. Birk, PhD, 2007-01-01, 2012-12-31
  • Graduate Research Assistant in Biochemistry & Molecular Biology, USF College of Medicine, Tampa, FL, John R. Hassell, PhD, 2000-01-01, 2007-12-31, The proteoglycan perlecan regulates long bone growth through interactions with developmental proteins in the growth plate.
  • Graduate Research Assistant, University of Florida College of Medicine Interdisciplinary PhD Program, Gainesville, FL, William Hauswirth, PhD; Margaret Wallace, PhD; William Kem, PhD, 1998-01-01, 1999-12-31
  • Undergraduate Honors Research Fellow in Biochemistry & Molecular Biology, USF College of Medicine and the James A. Haley VA Hospital, Tampa, FL, William R. Gower, PhD, 1996-01-01, 1998-12-31, Expression of the gastrointestinal regulatory peptides, i.e. atrial natriuretic peptides, and their receptors in a mouse model of congestive heart failure.

Personal Information

Title: Assistant Professor of Anatomy and Physiology

Awards

  • Biology department nominee for Junior Faculty Teaching Award (2019)
  • NC A&T ADVANCE IT Writing Retreat Fellow (2019)
  • NC A&T ADVANCE IT Award to attend annual STEM Women of Color Conclave (2017)
  • American Society for Cell Biology Minority Affairs Committee (ASCB MAC) 2017 Junior Faculty Career Development Workshop Award (2017)
  • Ruth L. Kirschstein Postdoctoral National Research Service Award (NRSA #F32AR056937) (2009-2012)
  • University of South Florida (USF) College of Medicine Latin American & Caribbean Scholarship (2003)
  • Fellowship, USF Interdisciplinary PhD Program in Cellular and Molecular Biology (IP2CMB), USF Institute for Biomolecular Science (2001-2003)
  • Phi Kappa Phi National Honor Society (1998)
  • Fred L. & Helen M. Tharp Endowed Scholarship (1997)
  • Golden Key National Honor Society (1996)
  • Annual USF Honors Convocation (1995-1998)
  • Dr. Martin Luther King, Jr. Scholar Award (1994)

Timeline

Senior Research Fellow in Bone and Extracellular Matrix

National Institute of Child Health and Human Development
01.2013 - 01.2016

Research Associate in Molecular Pharmacology & Physiology

Morsani College of Medicine at University of South Florida (USF)
01.2012 - 01.2013

Postdoctoral Research Fellow in Pathology & Cell Biology

Morsani College of Medicine at USF
01.2007 - 01.2012

Graduate Research Assistant in Biochemistry & Molecular Biology

USF College of Medicine
01.2000 - 01.2007

Graduate Research Assistant

University of Florida College of Medicine Interdisciplinary PhD Program
01.1998 - 01.1999

Undergraduate Honors Research Fellow in Biochemistry & Molecular Biology

USF College of Medicine and the James A. Haley VA Hospital
01.1996 - 01.1998

Assistant Professor of Anatomy and Physiology

North Carolina A&T State University

Doctor of Philosophy - Medical Science, Biochemistry & Molecular Biology

Morsani College of Medicine at the University of South Florida (USF)

Bachelor of Science - Biology

Judy Genshaft Honors College at USF
Simone Marsha-Lee Smith