Stacie E. Hughes

I have led and assisted in diverse scientific projects focused on meiotic biology. Utilizing genetics, molecular biology, cytology, and biochemistry, these projects have fostered collaborations with multiple cores at the Stowers Institute. Throughout my time in the Hawley lab, I have authored nine research papers and reviews as the first author and contributed to the publication of several other scientific projects. Additionally, I have presented my work internally and at various scientific meetings. My extensive experience includes supervising and mentoring junior scientists, including undergraduate students. I have also provided valuable support to fellow lab members in preparing manuscripts, talks, and grants while ensuring compliance with the Stowers ODR policy. As a research specialist prepared for advanced roles, I possess strong skills in data analysis, experimental design, and scientific writing. My approach is characterized by a strong focus on collaboration and achieving outcomes. With a reputation for critical thinking, problem-solving, and effective communication, I am known for being reliable and adaptable to changing project needs. Knowledgeable [Desired Position] with robust background in research methodologies and data analysis. Successfully led multiple research projects, contributing to significant advancements in field. Demonstrated expertise in problem-solving and critical thinking, consistently delivering high-quality insights.

• Meiosis: The elusive sister chromatid repair., Current Biology, 2021, 31, 9, R454-R456
• Alternative Synaptonemal Complex Structures: Too Much of a Good Thing?, Trends in Genetics, 2020, 36, 11, 833-844
• Meiosis: Location, Location, Location, How Crossovers Ensure Segregation., Current Biology, 2020, 30, 7, R311-R313
• Female Meiosis: Synapsis, Recombination, and Segregation in Drosophila melanogaster., Genetics, 2018, 208, 3, 875-908
• Live Imaging of Meiosis I in Late-Stage Drosophila melanogaster Oocytes., Methods in Molecular Biology, 2017, 1471, 255-264
• Heterochromatin: a rapidly evolving species barrier., PLoS Biology, 2009, 7, 10, e1000233
• The measurement and analysis of age-related changes in Caenorhabditis elegans., The C. elegans Research Community, Wormbook, 2008, 1-21, http://www.wormbook.org

• A transcriptomics-based RNAi screen for regulators of meiosis and early stages of oocyte development in Drosophila melanogaster., G3 (Bethesda), 2024, 14, 4, jkae028
• The E3 ubiquitin ligase Sina regulates the assembly and disassembly of the synaptonemal complex in Drosophila females., PLoS Genetics, 2019, 15, 5, e1008161
• Regulation of Polo Kinase by Matrimony Is Required for Cohesin Maintenance during Drosophila melanogaster Female Meiosis., Current Biology, 2020, 30, 4, 715-722.e3
• Discovery of supernumerary B chromosomes in Drosophila melanogaster., Genetics, 2014, 196, 4, 1007-16
• Topoisomerase II is required for the proper separation of heterochromatic regions during Drosophila melanogaster female meiosis., PLoS Genetics, 2014, 10, 10, e1004650
• Gamma-tubulin is required for bipolar spindle assembly and for proper kinetochore microtubule attachments during prometaphase I in Drosophila oocytes., PLoS Genetics, 2011, 7, 8, e1002209
• Binding of Drosophila Polo kinase to its regulator Matrimony is noncanonical and involves two separate functional domains., Proceedings of the National Academy of Science USA, 2013, 110, 13, E1222-31
• The Multiple Roles of Mps1 in Drosophila Female Meiosis., PLoS Genetics, 2007, 3, 7, e113
• The inhibition of polo kinase by matrimony maintains G2 arrest in the meiotic cell cycle., PLoS Biology, 2007, 5, 12, e323
• Congression of achiasmate chromosomes to the metaphase plate in Drosophila melanogaster oocytes., Developmental Biology, 2009, 325, 1, 122-8
• Heterochromatic threads connect oscillating chromosomes during prometaphase I in Drosophila Oocytes., PLoS Genetics, 2009, 5, e1000348
• Genetic and pharmacologic factors that influence reproductive aging in nematodes., PLoS Genetics, 2007, 3, 2, e25
• Valproic acid extends worm lifespan., Aging Cell, 2008, 7, 3, 305-17
• Identification of mutations that delay somatic or reproductive aging of Caenorhabditis elegans., Genetics, 2011, 189, 1, 341-56