Vinitha Deepu

Postdoctoral Fellow with extensive knowledge of cardiovascular research . Hardworking with a strong understanding of molecular biology processes. Adaptable and hardworking individual with excellent problem-solving skills.

• Best Oral Presentation (Student) Award for oral presentation titled “Cyclophilin A impairs efferocytosis and advances atherosclerotic lesions" in the 34th Kerala Science Congress organized by Kerala State Council for Science, Technology and Environment (KSCSTE) held on 27-29 January 2022 at Trivandrum
• Global Health Travel Awards” for free registration to “Keystone Symposia’s- eSymposia on Obesity: From Cell to Patient - EK17” for eposter presentation titled “ Cyclophilin A through activation of mitochondrial caspase 3 induces apoptosis in macrophages and enhances aortic lesions in high fat diet fed rabbits” held February 1-3 at Silverthorne, Colorado, USA
• Naranjan Dhalla Best Poster Awards for “Cyclophilin A promotes macrophage apoptosis by mitochondrial cascade activation" in the International Conference of Cardiovascular Sciences (ICCS 2020) organized by Delhi Pharmaceutical Sciences and Research university held on 21-23 February, 2020.
• Naranjan Dhalla best poster award for “Cyclophilin A induces apoptosis and impairs efferocytosis of high glucose activated macrophages” at International Academy of Cardiovascular Sciences (IACS-India Section) on Translational Research in Cardiovascular Science held at Bangalore on February 15-17, 2019
• Naranjan Dhalla Best Poster Awards for “Cyclophilin A promotes macrophage-derived foam cell formation in high glucose conditions by inducing ER stress" in the 10th International Conference of Academy of Cardiovascular Sciences (International Academy of Cardiovascular Science- India Section) on Recent Advances in Cardiovascular Sciences, at Madurai Kamaraj University, Madurai, Tamilnadu,8-10 February,2018.
• Naranjan Dhalla Best Poster Award for “Metformin attenuates lipid uptake in high glucose induced macrophages by inhibiting cyclophilin A" in the 9th International conference on Translational Research in Cardiovascular Sciences, at Vallabhai Patel Chest Institute, 9-11 February, 2017
• Naranjan Dhalla Best Poster Award for “Cyclophilin A enhances oxidized low-density lipoprotein induced foam cell formation in monocyte derived macrophages in high glucose condition", Vinitha A , Surya Ramachandran, C C Kartha at 8th International conference of International Academy of Cardiovascular Science- India section on Translational Research in Cardiovascular Science, Gujarath, February 5-6,2016.
• Received ICMR Senior Research Fellowship from 2018- 2021

• Deepu V, Rai V, Agrawal DK. Quantitative Assessment of Intracellular Effectors and Cellular Response in RAGE Activation. Archives of internal medicine research. 2024;7(2):80.
• Deepu V, Rai V, Agrawal DK. Interaction Between Genetic and Environmental Factors in the Pathogenesis of Cardiovascular Disease. InEnvironmental Factors in the Pathogenesis of Cardiovascular Diseases 2024 Aug 2 (pp. 351-382). Cham: Springer Nature Switzerland.
• Anandan V, Retnabai SK, Jaleel A, Thulaseedharan T, Mullasari A, Pillai MR, Kartha CC, Ramachandran S. Cyclophilin A induces macrophage apoptosis and enhances atherosclerotic lesions in high‐fat diet‐fed hyperglycemic rabbits. FASEB BioAdvances. 2021 May;3(5):305.
• Anandan V, Thulaseedharan T, Suresh Kumar A, Chandran Latha K, Revikumar A, Mullasari A, Kartha CC, Jaleel A, Ramachandran S. Cyclophilin a impairs efferocytosis and accelerates atherosclerosis by overexpressing CD 47 and down-regulating calreticulin. Cells. 2021 Dec 20;10(12):3598.
• Ramachandran S, Anandan V, Kutty VR, Mullasari A, Pillai MR, Kartha CC. Metformin attenuates effects of cyclophilin A on macrophages, reduces lipid uptake and secretion of cytokines by repressing decreased AMPK activity. Clinical Science. 2018 Mar 30;132(6):719-38.
• Vinitha A, Kutty VR, Vivekanand A, Reshmi G, Divya G, Sumi S, Santosh KR, Pratapachandran NS, Ajit MS, Kartha CC, Ramachandran S. PPIA rs6850: A> G single-nucleotide polymorphism is associated with raised plasma cyclophilin A levels in patients with coronary artery disease. Molecular and cellular biochemistry. 2016 Jan;412:259-68.
• Ramachandran S, Vinitha A, Kartha CC. Cyclophilin A enhances macrophage differentiation and lipid uptake in high glucose conditions: a cellular mechanism for accelerated macro vascular disease in diabetes mellitus. Cardiovascular diabetology. 2016 Dec;15:1-9.
• Ajithkumar GS, Vinitha A, Binil Raj SS, Kartha CC. Drug Resistance of Endocardial Endothelial Cells is Related to Higher Endogenous ABCG2. Cardiovascular toxicology. 2016 Oct;16:390-405.
• Ramachandran S, Venugopal A, Kutty VR, Chitrasree, VA, Mullassari A, Pratapchandran NS, Santosh KR, Pillai MR, Kartha CC. Plasma level of cyclophilin A is increased in patients with type 2 diabetes mellitus and suggests presence of vascular disease. Cardiovascular diabetology. 2014 Dec;13:1-8.

• Devendra K. Agrawal, M.Sc. (Chemistry), Ph.D. (Biochemistry), Ph.D. (Medical Sciences), MBA, MS (ITM), FAAAAI, FAHA, FAPS, FIACS, Professor and Director, Department of Translational Research, COMP, Western University of Health Sciences, Pomona, California, 91766, dagrawal@westernu.edu
• Vikranth Rai, MBBS, PhD, Department of Translational Research, COMP, Western University of Health Sciences, Pomona, California, 91766, vrai@westernu.edu
• Dr Abdul Jaleel, Scientist G, Rajiv Gandhi Centre for Biotechnology, Thiruvananthapuram, Kerala, 695014, jaleel@rgcb.res.in
• Dr Surya Ramachandran, Associate Professor-Medical Biotechnology, Gujarat Biotechnology University (GBU), Gandhinagar, Gujarat, 382355, surya.ramachandran@gbu.edu.in