Dr. Vishnu Sravan Bollu

Experienced Global Pharmacovigilance Scientist with a PhD and six (06) years of expertise in pharmacovigilance. Proficient in overseeing PV and Drug Safety activities, ensuring regulatory compliance. Skilled in directing aggregate report preparation, coordinating affiliate liaison, and excelling in Health Authority Inspections and Internal Audits representation. Dedicated to staff development and organizational enhancement, poised to drive safety excellence and implement innovative processes across the organization

• MedDRA training (Dec 2023)
• PV India Forum "Future Directions in PV" (Mar 2023)

1. Bollu VS, Barui AK, Mondal SK, Prashar S, Fajardo M, Briones D, Rodriguez-Dieguez A, Patra CR, Gomez-RuizS.Curcumin-loaded silica-based mesoporous materials: Synthesis, characterization and cytotoxic propertiesagainst cancer cells. Materials Science and Engineering: C. 2016 Jun 1;63:393-410.

2. Bollu VS, Nethi SK, Dasari RK, Rao SS, Misra S, Patra CR. Evaluation of in vivo cytogenetic toxicity ofeuropium hydroxide nanorods (EHNs) in male and female Swiss albino mice. Nanotoxicology. 2016 Apr20;10(4):413-25.

3. Bollu VS, Bathini T, Barui AK, Roy A, Ragi NC, MalOth S, Sripadi P, Sreedhar B, Nagababu P, Patra CR.Design of DNA-intercalators based copper (II) complexes, investigation of their potential anti-cancer activity andsub-chronic toxicity. Materials Science and Engineering: C. 2019 Dec 1;105:110079.

4. Bollu VS, Soren G, Jamil K, Bairi A, Yashmaina S. Genotoxic and histopathological evaluation of zinc oxidenanorods in vivo in Swiss albino mice. J Evol Med Dent Sci. 2016 Oct 17;5:6186-92.

5. Nethi SK, Barui AK, Jhelum P, Basuthakur P, Bollu VS, Reddy BR, Chakravarty S, Patra CR. Europiumhydroxide nanorods mitigate hind limb ischemia in wistar rats. Advanced Therapeutics. 2021Jun;4(6):2100016.

6. Nethi SK, Bollu VS, Patra CR. Rare Earth-Based Nanoparticles: Biomedical Applications, Pharmacological andToxicological Significance. Nanoparticles and their Biomedical Applications. 2020:1-43.

7. Rachamalla HK, Mondal SK, Deshpande SS, Sridharan K, Javaji K, Jaggarapu MM, Jinka S, Bollu VS, Misra S,Banerjee R. Efficient anti-tumor nano-lipoplexes with unsaturated or saturated lipid induce differential genotoxiceffects in mice. Nanotoxicology. 2019 Oct 21;13(9):1161-75.

8. Mukherjee S, Bollu VS, Roy A, Nethi SK, Madhusudana K, Kumar JM, Sistla R, Patra CR. Acute toxicity,biodistribution, and pharmacokinetics studies of pegylated platinum nanoparticles in mouse model. AdvancedNanoBiomed Research. 2021 Jul;1(7):2000082.

9. Barui AK, Nethi SK, Basuthakur P, Jhelum P, Bollu VS, Reddy BR, Chakravarty S, Patra CR. Therapeuticangiogenesis using zinc oxide nanoflowers for the treatment of hind limb ischemia in a rat model. BiomedicalMaterials. 2021 Mar 26;16(4):044103.

10. Appalanaidu K, Kotcherlakota R, Dadmal TL, Bollu VS, Kumbhare RM, Patra CR. Synthesis and biologicalevaluation of novel 2-imino-4-thiazolidinone derivatives as potent anti-cancer agents. Bioorganic & medicinalchemistry letters. 2016 Nov 1;26(21):5361-8.

11. Nethi SK, Barui AK, Bollu VS, Rao BR, Patra CR. Pro-angiogenic properties of terbium hydroxide nanorods:molecular mechanisms and therapeutic applications in wound healing. ACS Biomaterials Science &Engineering. 2017 Dec 11;3(12):3635-45.

12. Mukherjee S, Dasari M, Priyamvada S, Kotcherlakota R, Bollu VS, Patra CR. A green chemistry approachfor the synthesis of gold nanoconjugates that induce the inhibition of cancer cell proliferation through induction ofoxidative stress and their in vivo toxicity study. Journal of Materials Chemistry B. 2015;3(18):3820-30.

13. Mukherjee S, Sau S, Madhuri D, Bollu VS, Madhusudana K, Sreedhar B, Banerjee R, Patra CR. Greensynthesis and characterization of monodispersed gold nanoparticles: toxicity study, delivery of doxorubicin andits bio-distribution in mouse model. Journal of Biomedical Nanotechnology. 2016 Jan 1;12(1):165-81

14. Barui AK, Nethi SK, Basuthakur P, Jhelum P, Bollu VS, Reddy BR, Chakravarty S, Patra CR. Therapeuticangiogenesis using zinc oxide nanoflowers for the treatment of hind limb ischemia in a rat model. BiomedicalMaterials. 2021 Mar 26;16(4):044103.

15. Mukherjee S, Bollu VS, Roy A, Nethi SK, Madhusudana K, Kumar JM, Sistla R, Patra CR. Acute toxicity,biodistribution, and pharmacokinetics studies of pegylated platinum nanoparticles in mouse model. AdvancedNanoBiomed Research. 2021 Jul;1(7):2000082.

16. Barui AK, Bollu VS, Londhe S, Deshpande SS, Das S, Nethi SK, Alabbasi MM, Kuncha M, Kumar JM, SistlaR, Misra S. Toxicological evaluation of therapeutically active zinc oxide nanoflowers in pre-clinical mouse model.NanoImpact. 2023 Jul 1;31:100479.

1. Barui, Ayan K., Rajesh Kotcherlakota, Vishnu Sravan Bollu, Susheel K. Nethi, and Chitta R. Patra. "Biomedical and drug delivery applications of functionalized inorganic nanomaterials." In Biopolymer-Based Composites, pp. 325-379. Woodhead Publishing, 2017. 2.

2. Nethi, Susheel Kumar, Vishnu Sravan Bollu, and Chitta Ranjan Patra. "Rare Earth-Based Nanoparticles: Biomedical Applications, Pharmacological and Toxicological Significance." In Nanoparticles and their Biomedical Applications, pp. 1-43. Springer, Singapore, 2020.

                                                                                                                                                    Vishnu Sravan Bollu

1. Best poster award at 2nd International Toxicology Conclave (ICT 2016) with the title “Genotoxic investigationof pro-angiogenic europium hydroxide nanorods in Swiss albino mice”. CSIR-Indian Institute of ToxicologyResearch, Nov-2016, Lucknow.

2. Presented poster in 4th International Conference on Advanced Nanomaterial and Nanotechnology(ICANN-2015) with title “Cytogenetic toxicity study of pro-angiogenic nanorods in Swiss albino mice.” IndianInstitute of Technology, Dec-2015, Guwahati.

3. Presented poster in International Conference in Chemical Biology (ICCB-2014) on the topic Therapeuticmechanisms underlying the angiogenesis induced by rare earth nanoparticles Indian Institute of ChemicalTechnology, Feb-2014 (6-8), Hyderabad.

4. Best oral presentation award for the topic Recent Advances in Bone Cancer Treatment: PreventingMetastasis and Bone Loss in a state level conference “Recent Advances in Pharmaceutical Sciences.” 13March 2011, Karimnagar.

5. Participated as a delegate in 43rd Annual Conference of Indian Pharmacological Society & InternationalConference on Pharmacology and Translational Research Organized at National Institute of Nutrition, 14-16December 2010, Hyderabad.

6. Attended Preconference workshop on Writing Pre-Clinical Protocol & GLP Concepts heldin National Institute of Nutrition, 13 December 2010, Hyderabad.

7. Participated in International Conference on Recent Advances in Drug Discovery, in University College ofPharmaceutical Sciences, Kakatiya University. 22-24 October 2010.Waranagal.

8. Presented a scientific poster as co-author in International Seminar on Herbal Drug Research: Presentand Future Prospects on the topic “Pharmacological Evaluation of Curcumin for its NephroprotectiveActivity in 5/6 Nephrectomised rat model.” 4-6 December 2009, Ootacamund.