Summary
Overview
Work History
Education
Skills
Also known as...
Languages
Publications
Pending Publications Under Administrative Review
Professional Activities And Societies
Timeline
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Ya-Ping Shiau

Ya-Ping Shiau

Sacramento,CA

Summary

An accomplished scientist with 7+ years of Ph.D. and 4+ years of postdoctoral experience in oncology, specializing in drug development, nanomedicine, and cancer research. Proven ability to lead cross-functional projects, drive innovation, and mentor teams in high-impact research environments. Expertise in cell culture (primary cells, cell lines, drug-resistant cells), murine models, nanoparticle toxicity, and therapeutic evaluation of herbal extracts. Investigated exosome-mediated mechanisms in ocular diseases. Proficient in regulatory compliance, strategic project management, and advanced laboratory techniques. Strong analytical, leadership, and bilingual communication skills. Committed to adapting to evolving challenges and delivering scientific solutions with real-world impact.

Overview

16
16
years of professional experience

Work History

Postdoctoral Scholar

UC Davis Health
01.2021 - Current
  • Expertise in oncology, immunology, and drug delivery systems.
  • Published three review articles on cancer drug development focusing on autophagy regulation and nanoparticle application.
  • Authored two research papers on cancer treatment, exploring chemo drug combinations, phototherapy, and mechanistic investigations

Consultant

Theranostec Inc
01.2022 - 01.2023
  • Assisted in animal model establishment, experimental design, and study execution and supported grant acquisition.

Postdoctoral Researcher

Chung-Shan Medical University
01.2020 - 01.2021
  • Expertise in establishing murine models of uveitis, conducting mechanistic investigations on extracellular vesicles, and studying the therapeutic efficacy of quercetin in retinal degeneration.
  • Experienced in lab management, including guiding students' research directions and evaluating potential studies
  • Assist the laboratory to publish three research publications in a year

Master's and Ph.D. Students

National Taiwan University
01.2013 - 01.2020
  • Led research on the therapeutic efficacy of herbal extracts in the central nervous system, investigating their anti-inflammatory effects on primary microglial cells and potential treatments for autoimmune multiple sclerosis and allergic murine models.
  • Assisted in establishing SOPs for the cuprizone-induced demyelination murine model and contributed to securing ongoing grant funding post-graduation.
  • Published three peer-reviewed studies on the immunotoxicity of iron oxide nanoparticles and the immunopharmacology of herbal extracts.

Undergraduate Student

Chung Shan Medical University
01.2009 - 01.2013
  • Conducted research on herbal medicine extracts for male infertility treatment, evaluating their potential in reproductive recovery.
  • Provided technical support in tissue sample collection, facilitating seamless data acquisition and mentoring junior researchers to advance their studies

Education

Ph.D. - Veterinary Medicine

National Taiwan University
Taipei, Taiwan
01.2020

Undergraduate - Biomedical Sciences

Chung Shan Medical University
Taichung, Taiwan
01.2013

Skills

  • Cell culture (Cell line and Primary microglia and splenocyte and drug-resistance cells)
  • ELISA
  • Flow Cytometry
  • Western Blot/ PCR
  • Sphere cell and tumor organoid
  • Experimental autoimmune encephalomyelitis murine model and cuprizone-induced MS murine model
  • Cancerous murine model (Pancreatic and HNSCC)
  • Inflammatory murine model (Postoperative ileus and Endotoxin-induced uveitis)
  • Allergic murine model (Delayed-type hypersensitivity and Ovalbumin-sensitized mice)
  • Histological examination (HE and IHC)

Also known as...

English name: Alvina

Preferred name: Yai-ping Hsiao

Languages

Chinese (Mandarin)
Native or Bilingual
English
Full Professional

Publications

  • Quercetin Alleviates the Accumulation of Superoxide in Sodium Iodate-Induced Retinal Autophagy by Regulating Mitochondrial Reactive Oxygen Species Homeostasis through Enhanced Deacetyl-SOD2 via the Nrf2-PGC-1α-Sirt1 Pathway., Antioxidants., 2021, 10, 7
  • Differences in the Quantity and Composition of Extracellular Vesicles in the Aqueous Humor of Patients with Retinal Neovascular Diseases., Diagnostics., 2021, 11, 7 (First author)
  • Protective Effect of Quercetin on Sodium Iodate-Induced Retinal Apoptosis through the Reactive Oxygen Species-Mediated Mitochondrion-Dependent Pathway., International Journal of Molecular Sciences., 2021, 22, 8
  • Development of Nanosome-Encapsulated Honokiol for Intravenous Therapy Against Experimental Autoimmune Encephalomyelitis., International Journal of Nanomedicine., 2020, 15, 17-29 (First author)
  • Systemic exposure to a single dose of ferucarbotran aggravates neuroinflammation in a murine model of experimental autoimmune encephalomyelitis., International Journal of Nanomedicine., 2019, 14, 1229-124 (First author)
  • Iron oxide nanoparticles attenuate T helper 17 cell responses in vitro and in vivo., Int Immunopharmacol., 2018, 58, 32-39 (First author)

Pending Publications Under Administrative Review

  • Multifunctional and Scalable Nanoparticles for Bimodal Image-Guided Phototherapy in Bladder Cancer Treatment. Nano-Micro Letters
  • Fipronil Triggers Immunotoxicity through Reactive Oxygen Species-Driven Mitochondrial Apoptosis in Thymocytes. Toxics
  • Immunomodulatory Nanoplatforms with Multiple Mechanisms of Action in Cancer Treatment. Nanomedicine
  • Nanomedicine Approaches for Autophagy Modulation in Cancer Therapy. Small science

Professional Activities And Societies

  • Collaborated with international study at the University of Tokyo, Japan
  • Financial Support from the School of National Taiwan University
  • NTU's Department of Veterinary Medicine representative to attend the joint conferences with Tokyo University's Department of Agriculture and Life Sciences
  • Received international travel awards from the Ministry of Science and Technology (MOST) in Taiwan from 2015 to 2019

Timeline

Consultant

Theranostec Inc
01.2022 - 01.2023

Postdoctoral Scholar

UC Davis Health
01.2021 - Current

Postdoctoral Researcher

Chung-Shan Medical University
01.2020 - 01.2021

Master's and Ph.D. Students

National Taiwan University
01.2013 - 01.2020

Undergraduate Student

Chung Shan Medical University
01.2009 - 01.2013

Ph.D. - Veterinary Medicine

National Taiwan University

Undergraduate - Biomedical Sciences

Chung Shan Medical University
Ya-Ping Shiau