Yayu Liu

Resourceful Ph.D student passionate about advancing knowledge in cell biology through high-quality research. Self-motivated professional with excellent communication, planning and problem solving abilities. Extensive 8+ years working experience in biological laboratory and proficiency in various bio-related technique as well as animal experiments. Friendly and confident with the ability to work as a leader in the team.

Liu, Y. , Lei, P., Kashyap, A., Groth, T., Samuel R. &Andreadis, S.T Cleavage of Cadherin-11 Facilitates β-catenin Nuclear Translocation in Triple-Negative Breast Cancer and Promotes Metastasis, Paper in review （2021）

Liu, Y. , Lei, P., Row, S. & Andreadis, S.T. Cadherin-11 binds to PDGFRbeta and enhances cell proliferation and tissue regeneration via the PDGFR-AKT signaling axis. FASEB J 34, 3792-3804 (2020)

Liu, Y., Row,S, Alimperti, S., Agarwal, S.K. & Andreadis, S.T. Cadherin-11 is a novel regulator of extracellular matrix synthesis and tissue mechanics. J Cell Sci 129, 2950-2961 (2016).

Y. Liu , A. Kashyap, T. Groth, P. Lei, R. Samuel and S.T. Andreadis, Novel role of Cadherin-11 in breast cancer metastasis via cross-talking with Wnt-pathway , Annual Stem Cells in Regenerative Medicine Symposium (SCiRM), Buffalo, NY, May 21, 2021

Y. Liu , S. Row and S.T. Andreadis, Engagement of Cadherin-11 Promotes Cell Growth in Cooperation with Platelet Derived Growth Factor Receptor (PDGFR) via AKT Pathway, Annual Stem Cells in Regenerative Medicine Symposium (SCiRM), Buffalo, NY, Jun 21, 2019

Y. Liu , S. Row, P. Lei, S.T. Andreadis, Engagement of Cadherin-11 Promotes Cell Growth in Cooperation with Platelet Derived Growth Factor Receptor (PDGFR) via AKT Pathway, Tissue Engineering and Regenerative Medicine International Society (TERMIS AMERICAS), Orlando, FL, Dec 5, 2019

Y. Liu , S. Row and S.T. Andreadis, Engagement of Cadherin-11 Promotes Cell Growth in Cooperation with Platelet Derived Growth Factor Receptor (PDGFR) via AKT Pathway, Annual Stem Cells in Regenerative Medicine Symposium (SCiRM), Buffalo, NY, Jun 21, 2019

Y. Liu , S. Row and S.T. Andreadis, Cadherin 11 Modulate Fibroblast Growth Via Cooperation with Platelet Derived Growth Factor Receptor Beta, Annual Meeting of the American Institute of Chemical Engineers (AIChE), Pittsburgh, PA, Nov 1, 2018.

Y. Liu , S. Row, S. Agarwal, S.T. Andreadis, Cadherin 11 Modulate Fibroblast Growth Via Cooperation with Platelet Derived Growth Factor Receptor Beta, Annual Meeting of the Biomedical Engineering Society (BMES), Atlanta, GA, Oct 19, 2018.

Y. Liu , S. Row and S.T. Andreadis, Cadheirn 11 as a Novel Regulator of Cell Growth in Cooperation Platelet Derived Growth Factor Beta, Annual Stem Cells in Regenerative Medicine Symposium (SCiRM), Buffalo, NY, Jun 11, 2018

Y. Liu , S. Row, S. Agarwal, and S.T. Andreadis, “Novel role of Cadherin-11 in cell signaling via direct interaction with the PDGF receptor”, Annual Meeting of the Biomedical Engineering Society (BMES), Phoenix, AZ, Oct 14, 2017.

Y. Liu , K. Seldeen, B. Troen, S. Row, S. Agarwal and S.T. Andreadis, “Novel Role of Cadherin 11 in Extracellular Matrix Synthesis and Muscular Physiology”, Annual Meeting of the American Institute of Chemical Engineers (AIChE), San Francisco, CA, 2016.

Y. Liu , K. Seldeen, S. Row, B. Troen, S. Agarwal, and S.T. Andreadis, “Novel Role of Cadherin 11 in Extracellular Matrix Synthesis and Muscular Physiology”, Annual Meeting of the Biomedical Engineering Society (BMES), Minneapolis, MN, Oct 8, 2016.

Y. Liu , S. Row, S. Alimperti, T.A. George, S. Agarwal and S.T. Andreadis, “Cadherin-11 Regulates Mechanical Properties of Tissues and Collagen and Elastin Synthesis in-Vivo and in-Vitro”, Annual Meeting of the American Institute of Chemical Engineers (AIChE), Salt Lake, Utah, Nov8, 2015.

Y. Liu , S. Row, S. Alimperti, A.T. George, S.K. Agarwal, S.T. Andreadis, “Cadherin-11 Regulates Collagen and Elastin Synthesis in-vivo and in-vitro by Activating TGF-β and ROCK Pathway”, Annual Meeting of the Biomedical Engineering Society (BMES), Tampa, FL, Oct 7-9, 2015.

S. Row, S. Alimperti, M.T. Koobatian, Y. Liu , T.A. George, S. Agarwal and S.T. Andreadis, “Cadherin-11 Directs Mesenchymal Stem Cell Differentiation and Regulates Extracellular Matrix Production and Mechanical Properties of Myogenic Tissues in-Vivo and in Vitro”, Annual Meeting of the American Institute of Chemical Engineers (AIChE), Atlanta, GA, Nov 1, 2014.

S. Row, S. Alimperti, M. Koobatian, Y. Liu , T. George, S. Agarwal, and S.T. Andreadis, “Cadherin-11 Directs Mesenchymal Stem Cell Differentiation and Regulates Extracellular Matrix Production and Mechanical Properties of Myogenic Tissues in-vivo and in vitro”, Annual Meeting of the Biomedical Engineering Society (BMES), San Antonio, Oct 24, 2014.

• Mammalian cell and bacterial culture, cell line generation, lentiviral production, overexpression gene, SiRNA and CRISPR/Cas9 gene editing.
• Western Blot, Silver Staining, Immunostaining, Immuno-precipitation, ChIP-Seq, RNA-Seq, RT-PCR, Immunohistochemistry for cells and tissue (paraffin, frozen).
• Molecular biology and cloning including vector design, generation fusion protein, introducing point mutation as well as function domain depletion, sequencing, lentiviral production, transfection and transduction.
• Rodent handing and in vivo experimentation, anesthesia, injections; cell/tissue/organs isolation.
• Flow cytometry (BD Fortessa/Calibur), Confocal microscopy (Zeiss, Nikon), ChemiDoc image system (Bio-rad), Plate reader (BioTek), Nanodrop (Thermo Fisher), Trans-blot Turbo (Bio-rad), CFX96 Real-Time system (Bio-rad).
• Software including Qupath, LAS X, FCS Express, GraphPad, Microsoft Office, MATLAB, ImageJ.

• American Chemical Society (ACS)
• American Institute of Chemical Engineers (AIChE)
• Tau Beta Pi (Engineering Honor Society)
• Omega Chi Epsilon (Honor Society for Chemical Engineering)