Aimee Bielinski
Kansasville,WI
Summary
Past scientist with a background in operations and R&D looking to excel in a challenging yet rewarding opportunity to utilize experienced skills. Proficient in successful approaches for overseeing operations and problem-solving. Excellent skills in development standard operating procedures (SOP) and laboratory improvements.
Hard-working, quick-learning scientist in cardiovascular safety pharmacology. Proficient in leading, managing, executing, and optimizing early drug candidate research studies both as an individual and as a team leader. Extensive experience organizing and prioritizing multiple projects simultaneously. Highly skilled in a wide range of in vivo, ex vivo and in vitro laboratory techniques. Accomplished at writing study reports and contributing to published manuscripts to highlight key experimental results and analysis. Proficient in: GraphPad Prism, Libra, MARS, Microsoft Suite. Skilled at giving presentations to audiences of academic and industry representatives. Highly skilled in reviewing scientific literature/publications and executing practices to existing workflows. Collaborated in writing multiple manuscripts for publication.
Overview
11
11
years of professional experience
Work History
Associate Scientist II
AbbVie Laboratories – Cardiovascular Safety Pharmacology
03.2016 - 07.2024
- Proven ability to support various drug mechanistic projects simultaneously across a diverse cardiovascular assay set from in vitro to ex vivo
- Proficient in cross-functional collaboration within R&D to identify optimal screening assays for early detection of cardiotoxic drug candidates
- Collaboratively work with various groups within Abbvie on multiple projects to produce reliable data for drug selection
- Consistently deliver successful routine assays with timely results in a report format that enabled project team decision making.
- Maintained a safe and organized laboratory environment by adhering to best practices for chemical handling and waste disposal.
- Worked with cross-functional project teams to support productions of AbbVie.
- Managed multiple projects simultaneously, demonstrating exceptional time management skills while maintaining high levels of accuracy.
- Conducted thorough literature reviews to stay current on industry advancements and inform research directions.
- Promoted in 2021 due to performance commensurate of a higher grade level
- Strong ability to perform literature review to aid in independent and team research
- Independently design, conduct and comprehend early drug experiments with timely delivery of data to team projects.
Microbiology Quality Control Analyst
AbbVie Laboratories – Quality Assurance Operations
03.2016 - 05.2018
- Proficiently tested developing and manufactured drugs for various microbial contamination including E
- Coli, S
- Enteric, P
- Aeruginosa and S
- Aureus as well as yeasts and molds
- Properly analyzed microbial growth on samples and executed evaluation testing according to company standards
- Documented testing worksheets in adherence to F.D.A
- Regulations
- Design, develop, and implement novel methods and SOPs for In Vitro assays.
R&D Senior Lab Technician (Contract)
Abbott Laboratories Diagnostics Research & Development
07.2015 - 03.2016
- Chosen to work on a cross functional team on top of existing responsibilities, which involved investigating instrumented issues Instructed to helped Assay Integration Team to change out Pre-Trigger materials on ICQ instrument and running weekly diagnostic tests to validate the instrument was working properly.
Undergraduate Student I
Pathogenic Bacteriology Lab, University of Wisconsin-La Crosse
12.2013 - 12.2015
- Laboratory research was conducted independently after completion of initial training, apart from community projects
- Prepared and presented project summary reports containing analysis and MIC data for head research professor and fellow researchers
- Developed and executed novel laboratory protocols.
Education
Bachelor of Science - Microbiology
University of Wisconsin-La Crosse
La Crosse05.2015
Skills
- Lab scheduling
- Research and experiments
- Laboratory techniques
- Data accuracy
- Microsoft Excel
- Scientific Writing
- Safety processes and procedures
- Public Speaking
- Research design
- Data Analytics
- Cell Culture
Skills
Assays: Cell Contraction, Cell Titer-Fluor Viability, Mitochondrial Reactive Oxygen Species (ROS)-Glo, Seahorse, Odyssey Western Blot and Glucose Uptake-Glo, Nanion SyncroPatch Automated Patch Clamp, Sophion QPatch Automated Patch Clamp, RT-qPCR/PCR, Gel Electrophoresis, DNA/RNA Ext. Kits, Axion Microelectrode Array (MEA) with Human inducted pluripotent cell-derived cardiomyocytes, Incucyte Live-Cell Analysis, Luminex Multiplex, FirePlex Multiplex Immunoassay, Cell Culture: Various cell lines including canine, rodent, and human cells, Immortalized and Primary Multicellular Tissue Cultivation through various assays, Skilled at general lab techniques including Aseptic Technique in GMP environment, Organ/Tissue Bath with various tissues, Electrical Field Stimulation Tissue Bath, Locomotor Activity Assay, Gastrointestinal Activity Assay, Langendorff Isolated Heart Perfusion, Subcutaneous/Intraperitoneal Dosing, Oral Gavage (PO) Dosing
Publications
- Drug-induced QT prolongation: Concordance of preclinical anesthetized canine model in relation to published clinical observations for ten CiPA drugs, Journal of Pharmacological and Toxicological Methods, 05/2020, Koshman YE, Wilsey AS, Bird BM, et al., 10.1016/j.vascn.2020.106871, 32360993
- Disconnect between COX-2 selective inhibition and cardiovascular risk in preclinical models, J Pharmacol Toxicol Methods, 03/2023, Koshman YE, Bielinski AL, Bird BM, Green JR, Kowalkowski KL, Lai-Zhang J, Mahalingaiah PK, Sawicki JW, Talaty NN, Wilsey AS, Zafiratos MT, Van Vleet TR, 10.1016/j.vascn.2023.107251, 36792039
- Species comparison of compounds with known blood pressure effects in a vascular smooth muscle cell collagen contraction assay, J Pharmacol Toxicol Methods, 09/2023, Treadway J, Bielinski A, Zafiratos M, Polakowski J, 10.1016/j.vascn.2023.107290, 37442214
References
Available Upon Request
Timeline
Associate Scientist II
AbbVie Laboratories – Cardiovascular Safety Pharmacology
03.2016 - 07.2024
Microbiology Quality Control Analyst
AbbVie Laboratories – Quality Assurance Operations
03.2016 - 05.2018
R&D Senior Lab Technician (Contract)
Abbott Laboratories Diagnostics Research & Development
07.2015 - 03.2016
Undergraduate Student I
Pathogenic Bacteriology Lab, University of Wisconsin-La Crosse
12.2013 - 12.2015
Bachelor of Science - Microbiology
University of Wisconsin-La Crosse
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