Andreshae Spiller
Austin,TX
Summary
Results-driven clinical laboratory professional with specialized experience in molecular and genetic testing workflows, including cell-free DNA (cfDNA), circulating tumor DNA (ctDNA) analysis and NGS support. Proven ability to manage high-volume patient samples with precision while ensuring compliance with HIPAA and CLIA standards. Adept at supporting genetic diagnostic processes, troubleshooting workflow issues, and collaborating with clinical teams to ensure timely and accurate results. Brings a strong commitment to patient care, data integrity, and continuous process improvement.
Overview
7
7
years of professional experience
Work History
Clinical Laboratory Operator II | Signatera COMM
Natera
2025.04 - Current
- Support commercial-scale testing operations for the Signatera assay, used for monitoring cancer recurrence and treatment response through circulating tumor DNA analysis.
- Assist in testing of patient samples according to standard operating procedure.
- Meet expected performance metrics within role as applicable.
- Responsible for maintaining updated understanding and knowledge of methods performed in the lab.
- Completes training and other deadlines on time.
- Recognizes, escalates, and troubleshoot equipment malfunctions and common processing errors according to the laboratory’s standard operating procedures.
- Recognizes, documents, and escalates protocol deviations in lab to lead/supervisor.
- Communicates with team and other departments
- Assists teammates in completing daily tasks.
- Adheres to Departmental Expectations.
- Participates in team meetings and performs other duties as assigned.
Clinical Laboratory Operator I | Extractions
Natera
2023.07 - 2025.04
- Performed high-volume patient sample processing supporting molecular diagnostic workflows.
- Conducted patient sample testing and nucleic acid extraction according to laboratory SOPs and Good Laboratory Practices (GLP).
- Maintained accurate documentation and sample tracking within laboratory systems to ensure testing integrity and compliance.
- Assisted with troubleshooting equipment malfunctions and procedural inconsistencies, escalating issues when necessary.
- Completed technical training and maintained proficiency across laboratory platforms and protocols.
- Perform circulating cell-free DNA (cfDNA) or nucleic acid extraction from patient plasma or other specimen types.
Assistant Branch Manager
Republic Finance
2019.01 - 2022.07
- Supported daily branch operations by coordinating staff workflows, monitoring performance metrics, and ensuring efficient task completion.
- Trained and mentored new and existing team members, providing guidance on procedures, compliance standards, and customer service expectations.
- Reviewed client documentation and financial records to ensure accuracy, completeness, and regulatory compliance.
- Managed high volumes of client accounts while maintaining organized documentation and detailed records within internal systems.
- Collaborated with leadership to identify process improvements that increased operational efficiency and service quality.
- Resolved complex customer concerns by analyzing account details and coordinating solutions with internal teams.
- Assisted with onboarding new employees and supporting team training initiatives.
- Maintained strict adherence to company policies, financial regulations, and documentation standards.
Education
Bachelor of Science - Biology
Alcorn State University
Lorman, MS2016-05
Skills
- Strong written and verbal communication
- Cross-team collaboration
- Advanced Time Management
- Independent and team-based work
- Attention to detail and accuracy
- Adaptability in fast-paced environment
- Quality Control & Sample Validation
- CLIA/CAP Compliance
- End-to-end NGS workflow ownership
- Assay troubleshooting & root cause analysis
- Validation & verification of new methods
- Data interpretation
- Analytical thinking
- Prioritization in high-volume environments
- Ownership & accountability
Timeline
Clinical Laboratory Operator II | Signatera COMM
Natera
2025.04 - Current
Clinical Laboratory Operator I | Extractions
Natera
2023.07 - 2025.04
Assistant Branch Manager
Republic Finance
2019.01 - 2022.07
Bachelor of Science - Biology
Alcorn State University