Andressa Reginato

My academic journey began with a bachelor’s degree in Nutrition from Unicamp (Brazil), where I first discovered my passion for laboratory research. This led me to pursue a master’s and PhD in Nutrition and Metabolism at the same university. I investigated how saturated fatty acids modulate autophagy and inflammation in various mouse tissues—including the hypothalamus, liver, and adipose tissue. Throughout this period, I gained extensive hands-on experience with molecular biology techniques, such as Real-Time PCR, Western blotting, and Flow Cytometry (BD Accuri).

During my PhD, I was awarded an international fellowship at the University of Toronto (Canada), where I worked with primary and immortalized neuronal and microglial cell lines, further expanding my skills in cell culture and experimental design.

Following this, I joined Albert Einstein College of Medicine (New York) to study metabolic improvements driven by a twice-a-night dietary intervention in mice. My work focused on analyzing immune cells from the stromal vascular fraction of adipose tissue using spectral flow cytometry (Cytek Aurora) to understand their role in body weight regulation in mice.

Currently, I work at Montefiore Medical Center in a clinical immunology lab, where I specialize in the phenotyping and quantification of lymphocytes from peripheral blood, bone marrow, and lymph nodes (Beckman Coulter - Navios). I work closely with the hematopoietic stem cell lab, analyzing CD34+ cells for transplantation, and CD3+ cells for CAR-T therapy. This role has deepened my knowledge in immunology, stem cell biology, and flow cytometry in a clinical setting.

I’m now eager to bring my combined academic and clinical expertise toward a supervisor position, contributing to translational studies and therapeutic development. I thrive in collaborative, multidisciplinary teams, and am passionate about using cutting-edge technology to advance science that impacts patient care.

2024, ICCS (International Clinical Cytometry Society) Christine Aguhar Scholarship recipient.

• Dr. Marciane Milanski, University of Campinas, marcia31@unicamp.br
• Dr. Denise Belsham, University of Toronto, d.belsham@utoronto.ca
• Dr. Adriana Colovai, Montefiore Medical Center, a.colovai@montefiore.org

Mattar P, Reginato A, Lavados C, Das D, Kalyani M, Martinez-Lopez N, Sharma M, Skovbjerg G, Skytte JL, Roostalu U, Subbarayan R, Picarda E, Zang X, Zhang J, Guha C, Schwartz G, Rajbhandari P, Singh R. Insulin and leptin oscillations license food-entrained browning and metabolic flexibility. Cell Rep. 2024 Jul 23;43(7):114390. doi: 10.1016/j.celrep.2024.114390.

Reginato A, Veras ACC, Baqueiro MDN, Panzarin C, Siqueira BP, Milanski M, Lisboa PC, Torsoni AS. The Role of Fatty Acids in Ceramide Pathways and Their Influence on Hypothalamic Regulation of Energy Balance: A Systematic Review. Int J Mol Sci. 2021 May 19;22(10):5357. doi: 10.3390/ijms22105357. PMID: 34069652; PMCID: PMC8160791.

Reginato A, Siqueira BP, Miyamoto JÉ, Portovedo M, Costa SO, de Fante T, Rodrigues HG, Ignácio-Souza LM, Torsoni MA, Torsoni AS, Le Stunff H, Belsham DD, Milanski M. Acute effects of fatty acids on autophagy in NPY neurones. J Neuroendocrinol. 2020 Oct;32(10):e12900. doi: 10.1111/jne.12900. PMID: 33040385.

• I love to climb in my free time!