A versatile molecular and biochemical scientist with experience in both plant and animal systems. Expertise in lipid metabolism, enzymology, and signalling pathways. Expertise in advanced procedures like chromatography and mass spectrometry. Collaborative team player dedicated to driving progress in biological sciences.
Basic and translational research on understanding RNA synthesis and turnover in head and neck cancers,
Deciphering the roles of the family of human proteins that contain the Alpha Beta Hydrolase domain in regulating lipid metabolism
Understanding the G-Protein signaling pathway of plants in response to varied abiotic stress conditions.
Investigated the molecular intricacies of lipids and their impact on metabolic pathways to design effective plant-based supplements/diets for promoting health and preventing metabolic disorders.
Characterizing the biochemical and physiological roles of Alpha Beta Hydrolase Domain containing family of proteins in Arabidopsis.
Design and conduct experiments to study the structure, function, and metabolism of lipids in distinct biological systems (Plants, Yeast and Mice).
• Anitha Vijayakumar, Mrinmoyee Majumder, Shasha Yin, Charles Brobbey, Joseph Karam, Breege Howley, Philip H Howe, Stefano Berto, Lalima K Madan, Wenjian Gan, and Viswanathan Palanisamy,PRMT5-mediated arginine methylation of FXR1 is essential for RNA binding in cancer cells. 2023. Nucleic acid Research (Under review)
• Mrinmoyee Majumder, Harinarayanan Janakiraman, Paramita Chakraborty, Anitha Vijayakumar, Sari Mayhue, Hong Yu, Toros Dincman, Romeo Martin, Elizabeth O’Quinn, Shikhar Mehrotra and Viswanathan Palanisamy. RNA-binding protein HuR reprograms immune T cells and promotes oral squamous cell carcinoma 2023. Oral oncology (Accepted)
• Venkateshwari V, Vijayakumar A, Vijayakumar AK, Reddy LPA, Rajasekharan R (2018). Lipidome and transcriptome profiling of Portulaca oleracea: Characterization of lysophosphatidylcholine acyltransferase. Planta. DOI 10.1007/s00425-018-2908-8. IF: 4.1
• Pandey S, Vijayakumar A (2018) Emerging themes in heterotrimeric G-protein signaling in plants. Plant Sci. 170:292-300 IF: 4.7
• Heterotrimeric G-proteins as regulators of cellular redox status in plants. S Pandey, E McConnell, A Vijayakumar, SR Choudhury, L Hicks. Abstracts of papers of the American Chemical Society. International. 255 (2018)
• Iyappan R*, Vijayakumar A*, and Rajasekharan R (2018) The Arabidopsis Serine/Threonine/Tyrosine Protein Kinase Phosphorylates Oil Body Proteins that Regulate Oil Content in the Seeds. Sci. Rep doi:10.1038/s41598-018-19311-3 (*equal first author) IF: 4.3
• Kaur J, Roy Choudhury S, Vijayakumar A, Hovis L, Rhodes Z, Rob Polzin D, Blumenthal D, Pandey S. (2018) Arabidopsis type III Gγ protein AGG3 is a positive regulator of yield and stress responses in the model monocot Setaria viridis. Front. Plant Sci. doi: 10.3389/fpls.2018.00109 IF: 5.7
• Acharya BR, Choudhury SR, Estelle A, Vijayakumar A, Hovis L and Pandey S (2017) Optimization of phenotyping assays for the model monocot Setaria viridis. Front. Plant. Sci. doi: 10.3389/fpls.2017.02172 IF: 5.7
• Vijayakumar A, Panneerselvam V, Vijayakumar AK, Rajasekharan R (2016) The Arabidopsis ABHD11 Mutant Accumulates Polar Lipids in Leaves as a Consequence of Absent Acylhydrolase Activity. Plant Physiol, 170:180-193 IF: 8.9
• Vijayakumar A, and Rajasekharan R (2016) Distinct Roles of Alpha/Beta Hydrolase Domain Containing Proteins. Biochem. Mol. Biol. J. 2, 3: 18 IF:1.4
• Parthibane V, Iyappan R, Vijayakumar A, Venkateshwari V, Rajasekharan R (2012)
Serine/Threonine/Tyrosine Protein Kinase Phosphorylates Oleosin, a Regulator of Lipid Metabolic Functions. Plant Physiol. 159:95-10 IF:8.9
• Vijayaraj P, Jashal CB, Vijayakumar A, Rani, DSH. Rao VK, Rajasekharan R (2012) A Bifunctional Enzyme That Has Both Monoacylglycerol Acyltransferase and Acyl Hydrolase Activities. Plant Physiol. 160:667-83. IF: 8.9