Anuradha Rajulapati

Accomplished Scientist with a robust background in proteomics and genomics, honed at BIORA THERAPEUTICS and UT HEALTH NORTH EAST. Excelled in developing cutting-edge biomolecular detection technologies and leading critical research projects. Demonstrates exceptional analytical skills and a commitment to innovation in human health, complemented by strong leadership in laboratory management.

• Role of Catecholaminergic A2 neurons of nucleus of the solitary tract (NTS) in cardiovascular and respiratory adaptations to chronic intermittent hypoxia (CIH) in rats, Featured Topic: Neural Mechanisms In Cardiovascular Regulation, FASEB 2013, Gleneden Beach, OR
• Knockdown of tyrosine hydroxylase in the nucleus of the solitary tract reduces elevated blood pressure during chronic intermittent hypoxia, Invited talk; Featured Topic: Central Nervous System Modulation of Cardiorespiratory Responses to Hypoxia, EB 2013, Boston, MA
• Pharmacological Concentrations of Recombinant Factor VIIa Restores Hemostasis in Acquired Hemophilia Primarily Independent of Tissue Factor, Submitted to 56th Annual meeting and exposition 2015 of American Society of Hematology, Orlando, FL

• Pharmacological Concentrations of FVIIa restores hemostasis independent of tissue factor in antibody-induced Haemophelia mice, Journal of Blood, 11/2015, 126, 293
• Angiotensin receptor subtype AT1a and AMPA receptor subunit GluR2 mRNA levels are reduced in A2 neurons of nucleus of the solitary tract following chronic intermittent hypoxia, Experimental Biology 2013, Boston, MA
• Role of Catecholaminergic A2 neurons of nucleus of the solitary tract (NTS) in cardiovascular and respiratory adaptations to chronic intermittent hypoxia (CIH) in rats, Neural Mechanisms In Cardiovascular Regulation, FASEB 2013, Gleneden Beach, OR
• Knockdown of tyrosine hydroxylase in the nucleus of the solitary tract reduces elevated blood pressure during chronic intermittent hypoxia, High Blood Pressure Council Research, Washington DC, 2012

Visa Status: US citizen, Authorized to work anywhere in the USA

Available upon request

• B Verstockt, J Stylli, P Rahimian, A Rajulapati, K Ehring, D Thomas, J Sabino, M Ferrante, S Singh, S Vermeire, An increased baseline mucosal TNF burden linked to asalimumab non-response: opportunities for therapeutic drug monitoring, Journal of Crohn’s and Colitis, 14, Supplement_1, 01/2020, S531-S532
• Gaddam SK, Sundaram J, Rajulapati A, Pendurthi UR, Lella VMR, Factor VIIa interaction with EPCR modulates the hemostatic effect of rFVIIa in hemophelia therapy: mode of its action, Journal of Blood Advances, 06/01/17, 1206-1214, 10.1182/BLOODADVANCES.2016004143
• Gaddam SK, Sundaram J, Rajulapati A, Pendurthi UR, Lella VMR, Pharmacological Concentrations of recombinant factor VIIa restores hemostasis independent of tissue factor in antibody-induced Haemophelia mice, Journal of Thrombosis and Haemostasis, 02/14/16, 14, 3, 546-50, 26727350
• Kozyulina PY, Loskutov YV, Kozyreva VK, Rajulapati A, Ice RJ, Pugacheva EN, Pro-metastatic protein NEDD9 regulates individual cell migration via caveolin-1 dependent trafficking of integrins, Mol Cancer Res, 03/15/15, 13, 3, 423-38, 25319010
• Kozyreva VK, McLaughlin SL, Livengood RH, Calkins RA, Kelley LC, Rajulapati A, Ice RJ, Smolkin MB, Weed SA, Pugacheva EN, NEDD9 regulates actin dynamics through cortactin deacetylation in an AURKA/HDAC6-dependent manner, Mol Cancer Res, 05/26/14, 12, 5, 681-93, 24574519
• McLaughlin SL, Ice RJ, Rajulapati A, Kozyulina PY, Livengood RH, Kozyreva VK, Loskutov YV, Culp MV, Weed SA, Ivanov AV, Pugacheva EN, NEDD9 depletion leads to MMP14 inactivation by TIMP2 and prevents invasion and metastasis, Mol Cancer Res, 01/07/14, 12, 1, 69-81, 24202705
• Bathina CS, Rajulapati A, Franzke M, Mifflin SW, Knockdown of tyrosine hydroxylase in the nucleus of the solitary tract reduces elevated blood pressure during chronic intermittent hypoxia, Am J Physiol Regul Integr Comp Physiol, 09/18/13, 24049117

• Analytical and skilled Scientist with 12 years of experience in molecular biology, cell biology and immunology with solid problem solving, research and analysis skills with Master of Science degree in Chemistry.
• Adept at assisting with and conducting laboratory experiments on research projects within well-defined guidelines.
• Proven ability to maintain efficient operation of a laboratory, including providing supervision and guidance to junior level technicians.
• Keeps abreast of current publications relative to methods, techniques, and developments within area of research; collects, prepares, and analyzes specimens.
• Skilled at documenting work in a timely manner, assist in writing of research protocols, documents, and presenting data to audiences.
• Capable at quickly adapting to new responsibilities and job requirements outside of current scientific skill set.