Cindy Truong
Saugus,MA
Summary
Highly motivated scientist with over 5 years of experience in gene therapies, specializing in AAV, LNP, and VLP technologies. Proficient in ELISA, PCR, cell-based assays, and mammalian cell culture. Demonstrated success in developing effective characterization methods and actively contributing to the advancement of genetic medicines for improved healthcare outcomes.
Overview
8
8
years of professional experience
Work History
Principle Research Associate (Analytical Operations)
NVELOP THERAPEUTICS
06.2024 - Current
- Lead cross functional meetings with department managers within the company to coordinate sample testing based on company project timelines and communicate with team to coordinate sample testing as needed
- Build and manage trending charts for all assay controls and standards to ensure all assays are within assay specification
- Organize and streamline a sample submission process by using Micronic barcoded tubes to automate sample handling
- Execute biophysical characterization assays that include impurity, identity, and ELISA to support research and generate certificate of analysis (COA) for all drug products produced for in-vivo studies
- Collaborate with the automation team to ensure high throughput screening for routine assays
- Author standard operating procedures, as well as perform peer review of results reported in ELN
Senior Research Associate (Analytical Development)
NVELOP THERAPEUTICS
06.2023 - 06.2024
- Execute, implement, and document characterization assays for identity, impurity which include ELISA, dPCR, DNA and protein quantification, HCP, etc
- Collaborate with departments and cross-functional teams to answer technical and scientific questions through team-based experiments
- Support different stages of assay development, feasibility, robustness, and prequalification
- Manage analytical reagent inventory including reference standard materials as per regulatory standards
- Author and revise standard operating procedures, as well as perform peer review of results reported in electronic laboratory notebook (ELN)
Senior Associate Scientist (Analytical Development)
ONCORUS INC
10.2022 - 09.2023
- Work with team members to align with career and company goals in addition to ensuring high reproducibility in method performance
- Design and provide analytical support for assay optimization, development, prequalification, and technology transfer for characterization of viral products and impurities
- Generate and maintain mammalian cell banks from various cell lines to develop various potency methods for drug product candidates
- Screen various technologies that can detect cytotoxicity and cytopathic effects from various transfection methods
- Generate stability protocols and reports for all stability studies performed in the analytical development lab
- Oversee and maintain all chemical safety data sheets (SDS) onsite and assist with chemical spills in the laboratory as Chemical Safety Officer
Associate Scientist II (Analytical Development)
ONCORUS INC
06.2021 - 09.2022
- Perform full analytical testing to support oHSV and/or LNP product characterization that include plaque forming assays, cell-based expression assays, ELISAs, qPCR, gel electrophoresis, DLS
- Maintain various mammalian cell lines, critical laboratory reagents, and troubleshooting of advanced equipment
- Collaborate cross functionally with Process Development and Research teams to support process development and discovery program studies
QC Analyst Analytics
HOMOLOGY MEDICINES
12.2019 - 06.2021
- Perform routine QC testing including, but not limited to: ddPCR, ELISA, HPLC, CE, cell-based assays, bioburden, endotoxin, plate reading, and TOC
- Assist with the design, development and implementation of quality analytical training programs and training new employees
- Author and revise SOPs/Forms and other relevant controlled documentation, as well as perform peer review of both internal and externally generated data
- Participate in laboratory equipment qualification activities, as needed, and ensure laboratory operational readiness and assists with troubleshooting/continuous improvement as needed
QC Chemical Testing Analyst
LEMAITRE VASCULAR
05.2019 - 11.2019
- Performed in-process and product release chemical analysis using various analytical techniques for other analyst’s data results
- Performed Gas Chromatography (GC) and HPLC analysis for in-process testing materials
- Operated all test equipment, including maintaining calibration, quality control, samples and reagent inventory, routine maintenance and troubleshooting
- Assisted with the planning, preparation, and execution of validation protocols
- Wrote Standard Operating Procedure (SOP) for new procedures and improvement for current ones
Laboratory Assistant
Fisher College
09.2016 - 05.2019
- Prepared buffers-and media preparation for bacterial plating and produced SDS PAGE electrophoresis gels
- Maintained laboratory equipment and consumables for the laboratory
- Supported the team with lab preparation such as aliquoting enzymes, diluting TBE buffer, setting up the lab benches for each class including Genetics, Forensics, General Biology I & II, Biochemistry, and Cell & Molecular Biology
- Optimized previously generated data for transformation of EColi bacteria in LB/Ara/Amp media and wrote a new standard operating procedure for the analysis of this study
Education
Bachelor of Art - Biology
Fisher College
Boston, MA05.2019
Skills
- Research and analysis
- Data interpretation
- ELISA
- ddPCR
- Mammalian Cell Culture
- Potency
- Control Trending
- Nano Track Analysis
- Gel Electrophoresis
- Method Development
- Method Qualitification
- Team collaboration
- DNA Extraction
- Sample processing
- Powerpoint
- Protocol development
- Benchling
- JMP
- Graph Prism
- Quality control methodologies
- Test automation
- QC testing
- Problem-solving
- Attention to detail
- Excellent communication
- Organizational skills
- Reliability
Languages
Vietnamese
Professional Working
Timeline
Principle Research Associate (Analytical Operations)
NVELOP THERAPEUTICS
06.2024 - Current
Senior Research Associate (Analytical Development)
NVELOP THERAPEUTICS
06.2023 - 06.2024
Senior Associate Scientist (Analytical Development)
ONCORUS INC
10.2022 - 09.2023
Associate Scientist II (Analytical Development)
ONCORUS INC
06.2021 - 09.2022
QC Analyst Analytics
HOMOLOGY MEDICINES
12.2019 - 06.2021
QC Chemical Testing Analyst
LEMAITRE VASCULAR
05.2019 - 11.2019
Laboratory Assistant
Fisher College
09.2016 - 05.2019
Bachelor of Art - Biology
Fisher College
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