Summary
Overview
Work History
Education
Skills
Accomplishments
Timeline
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Craig Smith

Sayreville,NJ

Summary

Driven by a passion for scientific innovation and excellence in education, I've leveraged my expertise in histological evaluations and team leadership to significantly enhance project outcomes in the pharmaceutical industry and beyond. My work has not only increased screening capacities by 60% but also fostered a stimulating learning environment, raising student achievements in STEM fields.

Overview

32
32
years of professional experience

Work History

Scientist

Insmed/IProfessional
01.2023 - Current
  • Plan, coordinate, and execute pharmacodynamic studies in rodents.
  • Administer therapeutic agents to rodents through a variety of routes (including intraperitoneal, intravenous, oral, intra-tracheal, subcutaneous, intracerebroventricular).
  • Perform blood and tissue collections.
  • Conduct advanced characterization assays including in vivo.
  • Collaborate closely with in vivo team members, vivarium staff, and ex vivo analysis teams. Analyze and present data to project teams.
  • Author and review protocols, electronic notebook entries, technical reports, and scientific publications.
  • Maintain proper documentation of study procedures and results.
  • Adhere to all local, state, and federal guidelines concerning the use of animals in research.

Specialist -1

Ortho Clinical Diagnostics
05.2022 - 01.2023
  • Execute manufacturing processes according to standard operating procedures while maintaining working knowledge of cGMP requirements to ensure adherence to policies and regulations.
  • Support schedule adjustments to meet criteria production according to weekly workload.
  • Work with team to review departmental production schedules, work orders and related information to ensure batches are completed on schedule.
  • Set up and operate production equipment to produce work in process and finished goods.
  • Demonstrate training progression, and develop competencies to execute all levels of production.

Science Teacher

Newark Public Schools/Great Oaks Legacy Charter
08.2013 - 08.2021
  • Formulated and adopted project based science curriculum to encouraged student interest in Science, Technology, Engineering and Mathematics (STEM) and participation in middle and high school national science competitions.
  • Built platform for sustainable alternate agricultural technologies, including Hydroponics, Aquaponics and Aeroponics.
  • Prepared summative and formative assessments to gauge academic progress and conducted data analysis on student performance to evaluate efficacy of instruction. Raised final science test scores by 10% and 12% in consecutive years based on initial test scores.
  • Demonstrated positive and effective classroom management skills and communicated with students and parents regarding academic progress, assignments and behavior.
  • Leveraged diverse learning strategies to prepare students for higher-level education requirements

Research Scientist

Sanofi US
05.2000 - 12.2012
  • Conducted in-vivo pharmacology experiments in areas of Asthma and Chronic Obstructive Pulmonary Disease (COPD).
  • Increased screening capacity from 40 subjects per week to 500 subjects per week in one year, becoming the number 1 site for in-vivo pulmonary functioning screening.
  • Checked efficacy of compounds to inhibit effects of bronchial constriction in test subjects and reduce inflammation caused by COPD.
  • Developed pulmonary functioning laboratory utilizing guinea pig and mouse plethysmographs and trained team members to perform all surgical cannulations for pulmonary monitoring.
  • Traveled internationally to other sites to set up and lead research associates in key experiments with hundreds of test subjects and generated high quality data.
  • Guaranteed all data met stringent quality control standards.
  • Developed effective working relations with groups, individuals, other research facilities to advance compounds to clinical trials.
  • Wrote reports, reviews and summaries regarding efficacy of small molecules on Asthma and COPD. Presented data to management and at conferences.

Scientist II

Wyeth-Ayerst Research
01.1993 - 06.1999
  • Conducted experiments in areas of Cardio-Vascular Diseases and Women's Health.
  • Developed sophisticated in-vivo models of Air and Balloon angioplasty, prioritized project tasks after discussions with department lead and increased screening capacity by 60% in first year.
  • Utilized histological techniques to verify compound efficacy in reducing atherosclerotic plaque formation in vessel walls.
  • Developed and utilized in-situ-hybridization techniques to identify key elements present in plaque formation. Trained colleagues in histological preparation and utilization of technology to evaluate slides.
  • Developed and implemented oral gavage, IP, subcutaneous, osmotic pump diffusion, and intravenous dosing techniques to administer compounds to test subjects.

Education

Bachelor of Science - Biology

Fairleigh Dickinson University
Teaneck, NJ

Skills

  • Utilized crosscutting concepts to expand student understanding of core ideas in science and engineering practices
  • Expertise in inducing vascular wall injury, and histological evaluation of plaque formation
  • Trained and managed teams of both scientists and students to execute large scaled studies and projects
  • Expertise in small animal surgeries /necropsy and multiple animal dosing techniques (IP, SC, IV, and GI)
  • Knowledgeable in tissue culture, flow cytometry and ELISA Assay setup and execution
  • Knowledgeable in development of pharmaceutical grade reagents

Accomplishments

    Dozens of outstanding achievement awards for advancement of compounds to clinical phase.

    Developed high throughput in-vivo models and established pulmonary functioning labs. Innovated surgical procedures for in-vivo studies and developed techniques for administering doses to study subjects.

    Contributed to the publication of several Scientific articles.

    Provost Award recipient

    NAACP Special Achievement Award recipient

    University Honors Program

Timeline

Scientist

Insmed/IProfessional
01.2023 - Current

Specialist -1

Ortho Clinical Diagnostics
05.2022 - 01.2023

Science Teacher

Newark Public Schools/Great Oaks Legacy Charter
08.2013 - 08.2021

Research Scientist

Sanofi US
05.2000 - 12.2012

Scientist II

Wyeth-Ayerst Research
01.1993 - 06.1999

Bachelor of Science - Biology

Fairleigh Dickinson University

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