Durga Shankar Sharma
Postdoctoral Researcher
Coralville,IA
Summary
More than nine years of academic lab experience. Trained and experienced in molecular biology, cell biology, hematology, and immunology. Experienced with equipment operation training and presentations. My main career aim is to excel in research and development by applying my knowledge and technical skills.
Experienced with advanced research methodologies and data analysis in scientific studies. Utilizes cutting-edge techniques to drive innovative research outcomes. Track record of producing high-quality publications and collaborating effectively within multidisciplinary teams.
Dedicated scientist with strong expertise in research methodologies, data analysis, and scientific writing. Proven ability to collaborate effectively within multidisciplinary teams and adapt to evolving project needs. Skilled in experimental design, statistical analysis, and advanced laboratory techniques. Known for delivering impactful results and consistently driving projects to successful completion.
Overview
12
12
years of professional experience
11
11
years of post-secondary education
1
1
Language
Work History
Postdoctoral Researcher
University of Iowa
Iowa City, Iowa
10.2024 - Current
- Developed novel methodologies for data analysis, significantly improving research efficiency.
- Contributed to and actively participated in research conception, design and execution to address defined problems.
- Pursued independent and complementary research interests.
- Implemented cutting-edge technologies in the lab, staying at the forefront of scientific advancements in the field.
Postdoctoral Researcher
University of Michigan
Ann Arbor, Michigan
10.2022 - 10.2024
- Presented research findings at international conferences, fostering knowledge exchange among peers.
- Leveraged interpersonal and communication skills to mentor PhD, graduate and undergraduate students.
- Conducted thorough literature reviews to inform experimental design and maintain awareness of current trends in the field.
- Designed research projects and alternative approaches and discussed results with professor.
- Mentored junior researchers, enhancing their skills and supporting their career development.
- Developed novel methodologies for data analysis, significantly improving research efficiency.
- Maintained accurate records of research findings and provided statistical analysis of data results.
- Liaised with supervisor to review grants and manuscripts to develop potential publications.
- Enhanced research outcomes by designing and implementing innovative experiments in the lab.
- Optimized laboratory processes to ensure accurate results and efficient use of resources.
- Participated in lab meetings and project presentations.
- Prepared samples for analysis by performing complex sample preparation tasks.
- Developed new protocols and improved existing laboratory processes.
Postdoctoral Researcher
University of Toledo
Toledo, OH
12.2021 - 10.2022
- Designed effective experimental controls, ensuring robust conclusions from research studies.
- Conducted thorough literature reviews to inform experimental design and maintain awareness of current trends in the field.
- Designed research projects and alternative approaches and discussed results with professor.
Ph.D. (Biochemistry)
University of Hyderabad
Hyderabad, Telangana
07.2015 - 11.2021
- Advisor- Prof
- Ravi Gutti
- Thesis Title: Cannabinoid Receptor 2 Signaling: Role in Megakaryocyte Development and Neuroimmune Regulation
- Organized and detail-oriented with a strong work ethic.
- Demonstrated respect, friendliness and willingness to help wherever needed.
- Used strong analytical and problem-solving skills to develop effective solutions for challenging situations.
- Proven ability to learn quickly and adapt to new situations.
- Skilled at working independently and collaboratively in a team environment.
- Worked well in a team setting, providing support and guidance.
- Assisted with day-to-day operations, working efficiently and productively with all team members.
- Paid attention to detail while completing assignments.
Research Fellow
University of Hyderabad
Hyderabad, Telangana
07.2013 - 04.2014
- Conducted comprehensive literature reviews to identify knowledge gaps and inform future studies.
- Optimized experimental designs using advanced statistical techniques to ensure valid conclusions were drawn from collected data.
Education
Doctor of Philosophy - Biochemistry
University of Hyderabad
Hyderabad 07.2015 - 01.2021
Master of Science - Biochemistry
University of Hyderabad
Hyderabad 07.2012 - 10.2014
Bachelor of Science - Biotechnology
Soft Vision Institute of Biotechnology, Devi Ahilya Vishwa Vidyalaya
Indore, M.P. 07.2007 - 07.2010
Skills
- Western Blot
- Quantitative RT-PCR
- Immunofluorescence
- Confocal Microscope
- Immunoprecipitation
- Co-Immunoprecipitation
- Platelet Aggregometry
- Plasmid Preparation
- RNA Isolation
- DNA Isolation
- Cell Culture
- Flow Cytometry
- Transfection
- Co Transfection
- Pathway Analysis
- PCR
- Expression Profiling
- Microarray Analysis
Professional Services
Judge and Reviewer, 13th Annual Midwest Graduate Research Symposium, 03/16/24, Toledo, OH, USA
Mentored Students
- 2024, Joe Zheng, Project student, University of Michigan, USA
- 2023, Amanda Kucinskas, Summer project student, University of Michigan, USA
- 2022, Amol Koli, Undergraduate student, University of Toledo, Toledo, USA
- 2021, Uha Reddy, Project Student, University of Hyderabad, Hyderabad, India
- 2019, Ch. V.S. Anjali, Project Student, University of Hyderabad, Hyderabad, India
- 2018, Saranya, Project Student, University of Hyderabad, Hyderabad, India
- 2017, Subhankari Behra, Project Student, University of Hyderabad, India
Scientific Societies
Stem Cell Society Singapore (SCSS), 2018 - Present
Locations
- University of Iowa, Iowa City, IA, 52240, USA
- University of Michigan, Ann Arbor, MI, 48109, USA
- University of Toledo, Toledo, OH, 43606, USA
- University of Hyderabad, Hyderabad, Telangana, 500046, India
- Softvision Institute of Biotechnology, DAVV, Indore, Madhya Pradesh 452010 India
Personal Information
- Date of Birth: 03/20/91
- Marital Status: Married
Awards
- Award to present research work entitled 'Virodhamine: A Cannabinoid Receptor Agonist Induces Megakaryocyte Maturation and Pro-Platelet Production from In-vitro Megakaryoblastic Cells', Stem Cell Society Singapore (SCSS) Symposium, 12/09/20 - 12/11/20
- Travel award for research work entitled 'Virodhamine: A Cannabinoid Receptor Agonist to Enhance the Platelets Production from Megakaryocyte through Attenuation of Mitochondrial Function', Laboratory Medicine Congress & KSLM 60th Annual Meeting, 09/01/19
- Senior Research Fellow, University Grant Commission (UGC), India, 01/01/18
- Junior Research Fellow, University Grant Commission (UGC), India, 01/01/16
Publications
- Co-stimulatory effect of TLR2 and TLR4 stimulation on megakaryocytic development is mediated through PI3K/NF-ĸB and XBP-1 loop., Cellular Signaling, 10.1016/j.cellsig.2021.109924
- The Potential Therapeutic Role of Cannabinoids and Endocannabinoid System in Neuro-Immune Disorders., Journal of Neuroimmunology, 10.1016/j.jneuroim.2021.577501
- Virodhamine, an endocannabinoid induces megakaryocyte differentiation by regulating MAPK activity and function of mitochondria., Journal of Cellular Physiology, 10.1002/jcp.29949
- RUNX1 and TGF-β signaling Cross Talk Regulates Ca2+ Ion Channels Expression and Activity during Megakaryocyte Development., The FEBS Journal, 10.1111/febs.15329
- Endoplasmic reticulum stress induced apoptosis and caspase activation is mediated through mitochondria during megakaryocyte differentiation., Mitochondrion, 10.1016/j.mito.2020.115120
- Pituitary adenylate cyclase- activating polypeptide (PACAP): Differential effects on neonatal vs adult megakaryocytopoiesis., Thrombosis Research, 10.1016/j.thromres.2019.01.012
- Epigenetic mechanisms: Role in hematopoietic stem cell lineage commitment and differentiation., Current Drug Targets, 10.2174/1389201019666180215110010
- Current Updates on Role of Lipids in Hematopoiesis., Infectious Disorders - Drug Targets, 10.2174/1871526518666180215110010
Conferences
- Virodhamine: A Cannabinoid Receptor Agonist Induces Megakaryocyte Maturation and Pro-platelet Production from In-vitro Megakaryoblastic Cells., Stem Cell Society Singapore (SCSS) Symposium, 12/09/20 - 12/11/20
- Virodhamine: A Cannabinoid Receptor Agonist to Enhance the Platelets Production from Megakaryocyte through Attenuation of Mitochondrial Function., Laboratory Medicine Congress & KSLM 60th Annual Meeting, 09/01/19
- Cannabinoid receptors and its role in Megakaryocyte development., International Congress of Cell Biology-2018, 01/01/18
- Cannabinoid receptors: Role in Megakaryocyte development., BioQuest 2017 - SLS, 01/01/17
Timeline
Postdoctoral Researcher
University of Iowa
10.2024 - Current
Postdoctoral Researcher
University of Michigan
10.2022 - 10.2024
Postdoctoral Researcher
University of Toledo
12.2021 - 10.2022
Doctor of Philosophy - Biochemistry
University of Hyderabad
07.2015 - 01.2021
Ph.D. (Biochemistry)
University of Hyderabad
07.2015 - 11.2021
Research Fellow
University of Hyderabad
07.2013 - 04.2014
Master of Science - Biochemistry
University of Hyderabad
07.2012 - 10.2014
Bachelor of Science - Biotechnology
Soft Vision Institute of Biotechnology, Devi Ahilya Vishwa Vidyalaya
07.2007 - 07.2010
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