Ilze Smidt
Minneapolis,MN
Summary
Experienced Senior Research Assistant with in-depth knowledge of data collection, analysis, and interpretation. Strengths include strong analytical skills, problem-solving ability, and attention to detail. Proven record of contributing to research projects and publishing findings in academic journals. Demonstrated impact on previous work through contributions to successful project outcomes and implementation of efficient research methodologies.
Overview
6
6
years of professional experience
Work History
Senior Research Assistant II
Ellisen Lab, MGH & Harvard Medical School
Boston, MA
04.2022 - Current
- Maintained precise research documentation in support of a multi-center clinical trial.
- Collaborated with clinical teams to streamline tissue sample collection processes, as well as lead lab members in optimizing tissue sample utilization and analysis protocols.
- Performed translational analysis of patient specimens to identify mechanisms underlying early breast cancer pathogenesis.
- Executed deliverables for industry partners in cutting-edge antibody-drug-conjugate development.
Research Fellow
INBRE Fellowship, MDIBL & USMF
06.2020 - 10.2020
- Mentor: Timothy Breton, Ph.D, University of Maine at Farmington, comparative genomics research into the SREBs (Super-conserved Receptors Expressed in the Brain), utilizing genome browsers and alignment software to identify functional motifs & conserved residues between sub-classes of SREBs across 80 vertebrate fish species.
Education
B.S. - Neuroscience, Education, English Literature
Bates College
Lewiston, MaineSkills
- Flow cytometry
- Cell culture techniques
- Western blot analysis
- Immunofluorescence microscopy
- Clinical trial oversight
- Research documentation practices
- Mentorship and training
- Human tissue handling practices
- Tissue dissociation to single cell suspension
- PCR and RT-qPCR techniques
- Exosome isolation via ultracentrifugation
- Mouse colony management
- DNA gel electrophoresis methods
- Genome-wide CRISPR screening
- Growth curve analysis
- Dose-response curve analysis
Community Service
Community Outreach Fellow, Bates College Harward Center, Lewiston/Auburn, Maine, 09/01/18, 06/01/21
Publications
- Breast Cancer Inequities: The Intersectional Role of Social Epidemiology and Tumor Biology, Cancer Causes & Control, 2026
- Characterization of the G protein-coupled receptor family SREB across fish evolution, Nature Scientific Reports, 2021
- A Nectin-2 dimer specific antibody–drug conjugate suppresses tumor growth, In Submission at Molecular Cancer Therapeutics, 2026
- Cellular neighborhoods of interacting tumor, immune and vascular populations shape response to Sacituzumab Govitecan in triple-negative breast cancer, In Submission at Cancer Discovery, 2026
- Abstract P3-04-06: Genomic and transcriptomic profiling of BRCA mutation carrier tissues reveals the landscape of early pathogenesis of BRCA1/2-associated breast cancer,
- Abstract 4449: SIRT5 promotes chemoresistance through metabolic rewiring for nucleotide replenishing in refractory triple negative breast cancer,
- Abstract 6582: HD-PTP modulates anti-tumor immunity via extracellular vesicles in triple-negative breast cancer,
- Abstract 4353: Utilizing scRNA sequencing to understand biomarkers of response and resistance to Sacitizumab Govetican in localized TNBC,
- Abstract 767: Genomics and transcriptomics profiling of BRCA mutation carriers revealed the landscape of early pathogenesis of BRCA1/2-associated breast cancer,
Wet Lab Skills
- Flow Cytometry
- Cell Culture
- Cell Viability Assays
- Western Blot
- Immunofluorescence Microscopy
- RNA purification and reverse transcription to cDNA
- PCR & RTqPCR
- Exosome Isolation using Ultracentrifugation
- Mouse Colony Management
- Mouse Ear Tag and Tail Snip
- Immuno-precipitation
- DNA gel electrophoresis
- Transfection and Transduction
- Genome Wide CRISPR-Screen
- Growth Curve Generation
- Dose-Response Curve Generation
Timeline
Senior Research Assistant II
Ellisen Lab, MGH & Harvard Medical School
04.2022 - Current
Research Fellow
INBRE Fellowship, MDIBL & USMF
06.2020 - 10.2020
B.S. - Neuroscience, Education, English Literature
Bates College