Summary
Overview
Work History
Education
Skills
Websites
Accomplishments
Affiliations
Classes taught
Conference presentations
Peer Reviewed Publications
Textbook Chapters Published
References
Timeline
Generic

Jamie Corro

Albany,United States

Summary

Dedicated, curious, enthusiastic, and hardworking individual who is interested In the translational field of biomedical sciences.

My strong background is unique, as having worked in both molecular biology and analytical chemistry laboratories.

My familiarity with a wide range of instrumentation and techniques across various disciplines and specialties showcases my adaptability and readiness to work in diverse environments.

Strong interest in microscopy, genetics, drug discovery, and infectious diseases.

Advanced knowledge in microscopy techniques and developed and implemented protocols and procedures used across multiple research labs within the Wadsworth Center's Department of Genetics.

Eager to apply theoretical knowledge and hands-on experience gained through coursework, research projects, and internships to contribute effectively in a professional setting.

Detail-oriented team player with strong organizational skills. Ability to handle multiple projects simultaneously with a high degree of accuracy.

To seek and maintain full-time position that offers professional challenges utilizing interpersonal skills, excellent time management and problem-solving skills.

Possess excellent critical thinking, analytical, and communication skills. Committed to continuous learning and growth.

Seeking opportunities to leverage my education and skills to make a positive impact in biomedical and research sciences.

Career goal is to work in laboratory and environment with a strong focus on problem solving.

Recently completed my Ph.D. in Biomedical Science from the State University of New York At Albany (SUNY Albany).

Overview

16
16
years of professional experience

Work History

Graduate Student Researcher

State University at Albany, School of Public Health Biomedical Sciences Program/Wadsworth Center
08.2016 - Current

Dissertation Research: Elucidating the physiology of mycobacteria with ribosome hibernation induced by zinc starvation

Advisor: Dr. Anil Ojha

Rational: Ribosomes are essential biomolecular machines utilized for protein synthesis in every kingdom of life. Zinc is an important micronutrient controlling the expression and incorporation of different ribosomal proteins. In zinc-replete conditions, zinc-binding ribosomal paralogues (called C+) are incorporated into the ribosome. In zinc depleted, but still growth permissive conditions, non-zinc binding paralogues (called C-) replace their zinc binding counterparts in the ribosome. In zinc-starved and growth-restrictive conditions, the ribosomes stabilize as hibernating 70S monosomes through the coordinated binding of Mrf and Mpy, in which Mrf recruits Mpy to bind the ribosomal decoding center.

-Used genetic, biochemical, microscopic, single-cell analysis, in vitro, and in vivo studies to visually distinguish ribosome remodeling and ribosome hibernation and relate this to bacterial physiology and antibiotic tolerance.

-Constructed and visualized fluorescent reporters and proteins in Mycobacterium smegmatis and Mycobacterium tuberculosis using epifluorescent microscopy, confocal microscopy, and flow cytometry.

-Purified ribosomal proteins and ribosomal subunits and studied them using biocheimal assays and immunoblotting.

-Researched changes in bacterial physiology using biochemical assays and confocal microscopy.

-Used microfluidics and epifluorescent microscopy to visualize single-cell growth dynamics.

-Analyzed mouse lung tissue using confocal microscopy.

-Performed RNA Seq for Mycobacterium smegmatis and Mycobacterium tuberculosis samples to gain insight into changes in the transcription profile during ribosome hibernation.

-Used ICP-MS to determine the exact zinc concentration within bacterium.

-Prepared Mycobacterium tuberculosis samples for metabolite extraction and profiling

-Performed immunofluorescent staining and visualization of mouse lung sections infected with Mycobacterium tuberculosis and visualized changes in neutrophil recruitment and abundance using confocal microscopy

Office Assistant

Dr. Robin Feigelis, M.D. Internal Medicine and Cardiology
06.2008 - 08.2016

Performed general clerical, administrative, and lab duties under the direction of Dr. Feigelis, including: ICD-9, Medical Coding, prescription processing, management of patient records and appointments, centrifuging of blood samples, faxing, copying, and payment processing.

QC Analyst

Joule Scientific, assignment at Lycored
12.2015 - 05.2016

-Determined and assessed the potency and composition of vitamins, food additives, and supplements using HPLC.

-Determined particle size of analytes, formulations, beads, crystals, powders, and granular compounds.

-Determined moisture content of analytes, formulations, beads, crystals, powders, and granular compounds.

-Determined composition using FTIR spectra of products, analytes, formulations, beads, crystals, powders, and granular compounds.

Graduate Student Researcher

Arcadia University
02.2015 - 08.2015

-Researched conservation genetics of: the black colobus (Colobus satanas satanas), red colobus (Procolobus pennantii pennantii), and drill (Mandrillus leucophaeus poensis), 3 endemic primate species to Bioko Island primates that are currently endangered due to their hunting for bushmeat.

-Employed bioinformatically mined loci and primers from the rhesus macaque (Macaca mulatta) on chromosomes 1 and 2 to study primates and assess their genetic health.

Extracted DNA, amplified using a 3-primer method of PCR involving a forward primer with a tail, a reverse primer, and a labeled primer with a tail, verified using gel electrophoresis, and genotyped using a CEQ 8000.

-Analyzed statistics using Genepop to determine heterozygosity deficiency, deviations from Hardy-Weinberg Equilibrium, and inbreeding.

Trace Department Intern

Philadelphia Forensic Science Center
05.2014 - 07.2014

employed by the department in future rape cases to detect female epithelial cells and male sperm cells.

-Prepared serial dilutions of human semen and then stained samples using either the SPERM HY-LITER or the already employed Kernechtrot-Picroindigocarmine Stain (KPIC).

-Assessed the sensitivity of the assay and compared it to the KPIC.

-Viewed and analyzed specimens using fluorescent microscopy.

-Received fluorescent microscopy training and certification from Dina Mattes and SPERM HY-LITER training from Dr. Jennifer Old.

Analytical Chemistry Intern

Sun Chemical Corporation
05.2012 - 04.2013

-Used Gas Chromatography (GC-FID) to determine the presence of residual monomers remaining after polymerization reactions.

-Used Fourier Transform Infrared Spectroscopy (FTIR) for composition identification of both liquid samples and packaging substrates.

-Used Gel Permeation Chromatography (GPC) to determine molecular weight distribution of samples.

-Used Diferential Scanning Calorimetry to determine the glass transition of samples.

-Used Gas Chromatography Mass Spectrometry (GC-MS) to determine the identity of volatile components and monomers.

-Used High Pressure Liquid Chromatography (HPLC) to determine sample purity and residual monomers of glycol based polymers.

-Used headspace GC-MS to identify volatile organic solvents and headspace GC-FID to quantify them.

-Performed flashpoint determination using ERDCO SETAFLASH Model 01SF flashpoint and Miniflash FLA by Grabner flashpoint.

-Determined surface energy of substrates using Dynamic Absorption Tester (DAT).

-Determined acid and amine value numbers using standard acid base titrations.

-Investigated and conducted independent research project that sought to develop a method to determine the hydroxyl value number of materials soluble in dimethyl sulfoxide (DMSO), but not the standard acetonitrile, using a potentiometric titration.

-Determined total percent non-volatiles (TNV).

-Created low density polyethylene, polypropylene, and polyethylene terephthalate laminates using experimental paraffinic polymers from Japan and tested their efficacy and tensile strength using an INSTRON.

Laboratory Assistant/Volunteer

Jane Hubbard Lab at New York University School of Medicine
11.2011 - 05.2012

-Created the media plates that the Caenorhabditis elegans (C. elegans) lived.

Student Assistant

Dr. Eric Brenner, New York Univeristy
10.2010 - 05.2011

Responsible for stocking the lab with plates that contained: NGM medium and specialty plates used for RNAi and Ampicillin-Tetracycline Resistance assays.

-Created stock cholesterol, buffer, and amino acid solutions, created an inventory log of all chemicals, amino acids, and supplies, and helped with the initial design of a yeast two-hybrid assay.

-Helped develop laboratory curriculum for Dr. Brenner’s genetics class.

-Created stocks and records of C. elegans mutants, testing mating capabilities and phenotypic effects of mutant C. elegans for recessive lethality or deleterious, epistatic and lethal interactions of various mutations

-Inoculated C. elegan NGM plates, bacteria plated, and created their living medium.

Education

Doctorate in Biomedical Sciences, Introduction to Immunology, Lab Rotations in Biomedical Sciences, Molecular Cell Biology A-C, Emerging Infectious Diseases, Current Lit in Biomedical Sciences, Advanced topics in Biomedical Sciences: Cancer, Neuroscience, Stem Cells, Model Organisms, HIV, Drugs, and Vaccines, and Prokaryotic Biology, Virology, Biodefense lecture and laboratory, Infectious Disease Epidemiology, Responsible Conduct in Research, Advanced Topics in RNA Biology Modules I-III, Paradigms of Microbial Pathogenesis, Biomedical Horizons, Principles and Chemistry of RNA Biology -

State University of New York At Albany (SUNY Albany)
Albany, New York
08.2024

Masters of Science in Forensic Science (MSFS) in Forensic Science, Polymer Chemistry, Forensic Chemistry I, Forensic Chemistry II, Serology, Human Molecular Biology, Pharmacology, Toxicology, Equilibrium Analysis, Criminal Law and Ethics, Crime Scene Investigation, Microscopy, Forensic Pattern Analysis, Trace Evidence Analysis -

Arcadia University
Glenside, PA
08.2015

Bachelors - Biology

New York University
05.2012

Skills

  • Epifluorescent microscopy
  • Confocal microscopy (laser scanning and spinning disk)
  • Compound light microscopy
  • Stereomicroscopy
  • Polarized light microscopy
  • Bacterial culturing, plasmid preparation, transformation, cloning, and handling
  • Biochemical techniques, protein purification
  • Immunoblotting
  • Gel electrophoresis
  • DNA extraction, quantitation
  • PCR, primer design, Sanger sequencing
  • ELISA
  • RNA extraction, libration preparation, and RNA Seq
  • Flow Cytometry
  • Immunohistochemistry
  • FTIR, GPC, DSC, GC-MS, HPLC, LC-MS, GC-FID, INSTRON
  • Flashpoint analysis
  • Solid-phase extractions, liquid-liquid extractions
  • Molecular biology and genetic techniques
  • Good Laboratory Practices (GLP)
  • Data collection and organization
  • Scientific Writing
  • Data Collection
  • Qualitative Research
  • Research design
  • Data Interpretation
  • Quantitative Research
  • Experimental design
  • Experiment Design
  • Academic Networking
  • Hypothesis testing
  • Lab Techniques
  • FIJI
  • FlowJo
  • QuPath
  • R
  • AutoQuant
  • Chemstation
  • Mac and PC Literacy

Accomplishments

  • Salutatorian - June 2008, Park Ridge High School
  • National Honor Society - September 2007, Park Ridge High School
  • RNA Fellowship - August 2017, RNA Institute and SUNY Albany

Affiliations

American Society for Microbiology (ASM)

Classes taught

  • HSPH305, Biological Basis of Personal and Public Health, Bacteria and the Problem with Antibiotic Resistance, Guest lecturer, Spring 2020, Fall 2020, Spring 2021, Fall 2021, Spring 2022, Fall 2022, Spring 2023, Fall 2023, Spring 2024
  • BMS505, Biological Basis of Public Health, Tuberculosis, Teaching Assistant, Guest Lecturer, Fall 2019, Fall 2020, Fall 2021

Conference presentations

  • Visualization of zinc regulated ribosome remodeling and hibernation in Mycobacterium smegmatis, The RNA Symposium, Albany, NY, March 2019, Poster presentation
  • Zinc depletion leads to ribosome remodeling, hibernation, and bacterial dormancy Mycobacterium smegmatis, The RNA Symposium, Albany, NY, March 2020, Poster presentation
  • Visualization of dormancy induced by ribosome hibernation in zinc-starved mycobacteria, eSymposia-Tuberculosis: Science Aimed at Ending the Epidemic, Virtual, December 2020, Oral and poster presentation
  • Zinc regulated ribosome hibernation contributes to bacterial dormancy and persistence in mycobacteria, ASM Symposium, September 2022, Poster presentation
  • Ribosome hibernation factor induces isoniazid persisters of Mycobacterium tuberculosis in neutrophil-rich lung lesions, ASM Trainee Symposium, March 2023, Oral presentation
  • Ribosome hibernation factor induces isoniazid persisters of Mycobacterium tuberculosis in neutrophil-rich lung lesions, Boston Bacterial Meeting, June 2023, Oral presentation
  • Ribosome hibernation factor induces isoniazid persisters of Mycobacterium tuberculosis in neutrophil-rich lung lesions, Life Sciences Research Symposium XIV, October 2023, Oral presentation
  • Visualization of Non-Replicating Persisters of Mycobacterium tuberculosis in Lung Lesions, Gordon Conference on Microbial Stress Responses, July 2024, Oral presentation

Peer Reviewed Publications

Li, Y., Corro, J. H., Palmer, C. D. & Ojha, A. K. Progression from remodeling to hibernation of ribosomes in zinc- starved mycobacteria. Proc Natl Acad Sci USA 117, 19528–19537 (2020).


Li, Y. et al. Starvation sensing by mycobacterial RelA/SpoT homologue through constitutive surveillance of translation. Proc. Natl. Acad. Sci. U.S.A. 120, e2302006120 (2023).


ORCID ID:

https://orcid.org/0009-0008-8915-5733

Textbook Chapters Published

Li Y, Keshavan P, Corro JH, Koripella RK, Agrawal RK, Ojha AK. Purification of Hibernating and Active C- Ribosomes from Zinc-Starved Mycobacteria. Methods Mol Biol. 2021;2314:151-166. doi: 10.1007/978-1-0716-1460- 0_5. PMID: 34235651.

References

  • Valerie Bolivar, Professor, valerie.bolivar@health.ny.gov
  • Rich Cole, Professor, Committee Member, richard.cole@health.ny.gov
  • Anil Ojha, Principle Investigator (PI), Mentor, Professor, Anil.Ojha@health.ny.gov
  • Janice Pata, Professor, Committee Member, janice.pata@health.ny.gov

Timeline

Graduate Student Researcher

State University at Albany, School of Public Health Biomedical Sciences Program/Wadsworth Center
08.2016 - Current

QC Analyst

Joule Scientific, assignment at Lycored
12.2015 - 05.2016

Graduate Student Researcher

Arcadia University
02.2015 - 08.2015

Trace Department Intern

Philadelphia Forensic Science Center
05.2014 - 07.2014

Analytical Chemistry Intern

Sun Chemical Corporation
05.2012 - 04.2013

Laboratory Assistant/Volunteer

Jane Hubbard Lab at New York University School of Medicine
11.2011 - 05.2012

Student Assistant

Dr. Eric Brenner, New York Univeristy
10.2010 - 05.2011

Office Assistant

Dr. Robin Feigelis, M.D. Internal Medicine and Cardiology
06.2008 - 08.2016

Doctorate in Biomedical Sciences, Introduction to Immunology, Lab Rotations in Biomedical Sciences, Molecular Cell Biology A-C, Emerging Infectious Diseases, Current Lit in Biomedical Sciences, Advanced topics in Biomedical Sciences: Cancer, Neuroscience, Stem Cells, Model Organisms, HIV, Drugs, and Vaccines, and Prokaryotic Biology, Virology, Biodefense lecture and laboratory, Infectious Disease Epidemiology, Responsible Conduct in Research, Advanced Topics in RNA Biology Modules I-III, Paradigms of Microbial Pathogenesis, Biomedical Horizons, Principles and Chemistry of RNA Biology -

State University of New York At Albany (SUNY Albany)

Masters of Science in Forensic Science (MSFS) in Forensic Science, Polymer Chemistry, Forensic Chemistry I, Forensic Chemistry II, Serology, Human Molecular Biology, Pharmacology, Toxicology, Equilibrium Analysis, Criminal Law and Ethics, Crime Scene Investigation, Microscopy, Forensic Pattern Analysis, Trace Evidence Analysis -

Arcadia University

Bachelors - Biology

New York University
Jamie Corro