Summary
Overview
Work History
Education
Skills
Timeline
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JÉSSICA VASQUES RAPOSO VEDOVI

JÉSSICA VASQUES RAPOSO VEDOVI

Reading,MA

Summary

Experienced Research Scientist with over 12 years in genetic analysis (Next Generation Sequencing) and plasma biomarkers (SIMOA and ELISA), specializing in neurological diseases and viral infections. Ph.D. in Parasitic and Molecular Biology with expertise in Herpesvirus research, CRISPR/Cas9 antiviral strategies, and in vivo RNAi treatments for Herpetic Encephalitis. Skilled in multiplex qPCR diagnostics and antiviral studies, with a strong background in biosafety, molecular biology, and gene editing. Highly-motivated employee with desire to take on new challenges. Strong work ethic, adaptability, and exceptional interpersonal skills. Adept at working effectively unsupervised and quickly mastering new skills.

Overview

13
13
years of professional experience
1
1
Language

Work History

Postdoctoral Researcher

Universidade Federal do Estado do RJ, Rio De Janeiro, Rio De Janeiro
09.2021 - 09.2024
  • Executed and coordinated research projects in precision medicine for neurosciences
  • Identified genetic variants linked to clinical outcomes and radiological profiles in patients with neurodegenerative and inflammatory demyelinating diseases (IDD) of the CNS
  • Conducted exome analysis of Neuromyelitis optica patients
  • Monitored the entry and collection of biological samples from patients for research
  • Biomarker detection (ELISA and SIMOA assays) related to demyelinating diseases, neuroinflammatory conditions, and viral infections with neurological manifestations
  • Managed the genetic sequencing (NGS Illumina) platform and its activities
  • Trained staff in experiment execution
  • Supervised undergraduate, master's, and doctoral students.
  • Participated in conferences and presented research work
  • Engaged in teaching practices for undergraduate courses.

Doctoral Researcher

Fundação Oswaldo Cruz
Rio De Janeiro, RJ
03.2017 - 09.2021
  • Analyzed the antiviral activity of CRISPR/Cas9 against HSV-1 in vitro
  • Supervised undergraduate students
  • Attended conferences and presented research work in the field
  • Published the first report of triple Betaherpesvirus infection
  • Demonstrated that the CRISPR/Cas9 anti-HSV-1 complex effectively inhibited HSV-1 replication.

Master Research Fellow

FUNDAÇÃO OSWALDO CRUZ, BRAZIL | Rio De Janeiro, RJ
, DE
01.2015 - 01.2017
  • Developed a multiplex qPCR test for simultaneous detection of three
  • Betaherpesvirinae viruses, crucial for diagnosing herpesviruses in transplant patients and autoimmune diseases
  • Presented research at events, congresses, and field-specific conferences.

Student Researcher

FUNDAÇÃO OSWALDO CRUZ, Rio De, Janeiro, RJ
01.2012 - 01.2014
  • Infected BALB/c mice with HSV-1 to study viral effects
  • Assessed and compared HSV-1 viral loads of KOS and EK strains in
  • BALB/c mice through cell culture (p.f.u)
  • Demonstrated the use of siRNA in vivo to inhibit HSV-1 replication, reduce clinical signs of Herpetic Encephalitis (HSE), and increase survival time in mice.

Education

light chain in mild COVID-19 patients Molecular Psychiatry -

01.2024

DOI: 10.1038/s -

01.2023

DOI: 10.1016/j. -

01.2023

CRISPR/Cas-9 vector system: targets UL-39 and inhibits HSV -

01.2023

High Levels of NfL, GFAP, TAU, and UCH-L1 as Predictor Biomarkers in Acute COVID-19 Molecular Neurobiology -

01.2023

Exome Analysis Course -

Instituto Carlos Chagas - Fiocruz, ICC
01.2022

PhD - Molecular Biology

Fundação Oswaldo Cruz
09.2021

10.1007/s12035-023-03803-z. Molecular Mimicry between SARS-CoV-2 and CNS Autoimmune Disorders Microorganisms, 2023. DOI -

01.2021

doi: 10.1007/s -

01.2021

01.2020

10.1186 -

Montgomery College
01.2019

01.2018

Master of Science - Molecular Biology

Fundação Oswaldo Cruz
02.2017

Master's Degree - FAPERJ

Instituto Oswaldo Cruz
01.2017

COVID -

01.2015

DOI: 10.3851/IMP3016 -

01.2015

Bachelor of Science - Biology

Universidade Do Grande Rio
07.2014

Skills

  • Virology; Molecular Biology; Cell Culture; Gene editing; RNAi; Neuroscience; Immunology; ELISA; qPCR; Scientific writing;
  • Peer Reviews; Animal testing; Results Analysis; Laboratory equipment functions; Research and publication; Lab experiments
  • And research; Gel Electrophoresis; Primer design; DNA isolation; Plasmid synthesis; Experimental design; Data Interpretation;
  • Statistical Analysis; Training & Development; Variant investigation; Problem-solving abilities

Timeline

Postdoctoral Researcher

Universidade Federal do Estado do RJ, Rio De Janeiro, Rio De Janeiro
09.2021 - 09.2024

Doctoral Researcher

Fundação Oswaldo Cruz
03.2017 - 09.2021

Master Research Fellow

FUNDAÇÃO OSWALDO CRUZ, BRAZIL | Rio De Janeiro, RJ
01.2015 - 01.2017

Student Researcher

FUNDAÇÃO OSWALDO CRUZ, Rio De, Janeiro, RJ
01.2012 - 01.2014

light chain in mild COVID-19 patients Molecular Psychiatry -

DOI: 10.1038/s -

DOI: 10.1016/j. -

CRISPR/Cas-9 vector system: targets UL-39 and inhibits HSV -

High Levels of NfL, GFAP, TAU, and UCH-L1 as Predictor Biomarkers in Acute COVID-19 Molecular Neurobiology -

Exome Analysis Course -

Instituto Carlos Chagas - Fiocruz, ICC

PhD - Molecular Biology

Fundação Oswaldo Cruz

10.1007/s12035-023-03803-z. Molecular Mimicry between SARS-CoV-2 and CNS Autoimmune Disorders Microorganisms, 2023. DOI -

doi: 10.1007/s -

10.1186 -

Montgomery College

Master of Science - Molecular Biology

Fundação Oswaldo Cruz

Master's Degree - FAPERJ

Instituto Oswaldo Cruz

COVID -

DOI: 10.3851/IMP3016 -

Bachelor of Science - Biology

Universidade Do Grande Rio

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