Summary
Overview
Work History
Education
Skills
Bonzai Horticulture
Timeline
Generic

Laurence Webster

Aiken,SC

Summary

Versatile Chemist with management and leadership experience. Works with different types of chemicals, compounds, Instrumentation, processes and materials. Proficient in performing tests, documenting results, reviewing data, troubleshooting, and communicating in a timely and efficient manner while utilizing GMP with the goal of meeting deadlines. Well-organized and detail-oriented Senior Analyst with good management and planning abilities developed over 12+ years in Diagnostic, Small Molecule, and Peptide/Biopharma Industry.

Overview

29
29
years of professional experience

Work History

Quality Control Chemist III

Ambiopharm
06.2022 - Current
  • Perform all laboratory testing for release team with a primary focus on: HPLC(Purity and Related Impurities), UPLC(Assay), GC(Direct inject and Residual Solvents), MS, Bioassay, Elemental Analysis(%Peptide Content by Nitrogen Determination), and Raw Material Testing
  • Secondary responsibilities include writing and creating deviation reports, OOS investigations, initiating change controls, and QC Reviewer
  • Ordering samples for analytical testing and data sheets for reporting
  • Coordinating outside laboratory analysis for associated projects of which analyst is responsible
  • Creation of Instrument Methods, Processing Methods, Method Sets, and all manual and auto- integration associated with Empower III along with batch processing and individual processing
  • Testing phases include Crude, Intermediate/In-Process, and Finished Product/Release
  • Products Tested: Semaglutide, Liraglutide, Bivalirudin, and others.

Quality Control Supervisor/Quality Control Chemist

Harrington Pepsi
08.2019 - 05.2022
  • Responsible for all laboratory, production operations, and quality of all PepsiCo products site wide
  • Oversees all HPLC analysis for beverage content related to sugar, sugar substitutes, caffeine content, and preservative combinations
  • Designs testing for water purification, with emphasis on bromide content and new methods of bromate prevention
  • Oversees and supervises laboratory staff on daily testing and quality verification of products
  • Manages and verifies both the receipt and quality testing of in house High Fructose Corn Syrup, CO2 , and N2 gasses necessary for the production of Pepsi products
  • Assists in the development and formulation of new products
  • Responsible for placing products on hold and initiating root cause investigations for held products that are deemed out of specification
  • Utilizes HPLC analysis for batched product before it is produced to ensure it follow PepsiCo guidelines
  • Responsible for HPLC troubleshooting
  • Initiates both disclipinary action and Performance Improvement Plans (PIP) for employees
  • Resolves Employee disputes and refers those disputes up the management chain
  • Author and Reviewer of Laboratory and production SOP’s
  • Ensures GMP guidelines are followed and reinforced through training
  • Ensures the quality of all products by hourly verification of code nomenclature and configurations referencing time, date, and equipment that produced product
  • As a member of the food safety team, reports bi-weekly to the vice president of the company and president of operations on potential hazards, improvements, and resolution of issues regarding food safety.
  • Supported audits and led teams to fully investigate quality control processes and root out deficiencies.
  • Supervised and directed quality control personnel through effective mentoring, coaching and work delegation.

Quality Control Chemist II/Instrumentation Coordinator

CreoSalus,Inc
11.2017 - 06.2019
  • Oversees all validation of instrumentation (Installation Qualification, Operational Qualification, Performance Qualification)
  • Responsible for scheduling maintenance of equipment and all vendor and engineer visits for planned maintenance and repair
  • Schedules service and negotiates equipment repair and exchange with corporate service departments and regional managers of servicing companies
  • Itemized all equipment for annual Quality Control departmental budget
  • Instituted training programs with vendors for all laboratory personnel
  • Performs in-house repairs of instrumentation
  • Train personnel on the use of equipment
  • Responsible for documenting all service to instrumentation and coordinates all pre and post approval from corporate management
  • Responsible for reviewing and approving all service work completed by vendors
  • Responsible for submitting all service work to Quality Assurance
  • As an analyst, prepares samples for Peptide testing
  • This includes: Crude, Fraction analysis, Drug Substance, and Drug Product via LCMS,GC, and Elemental Analyzer
  • Updates all equipment around daylight savings time
  • Worked with IT department and management to upgrade all workstations to Windows 10 and Enterprise for all Thermo-Fisher equipment
  • Created and validated the companies Nitrogen protocol
  • Coordinated all testing supplies and guidelines with gas vendors, Restek senior technicians, and division heads of the United States Pharmacopea.
  • Advised chemists and laboratory technicians on existing and emerging quality control methods to enhance testing and research capabilities.
  • Collaborated with laboratory technicians, production personnel and customers to improve product quality and functionality.

Quality Control Chemist I

Sigma-Tau/Exelead Biopharma
09.2016 - 10.2017
  • Carried out GC, HPLC, UPLC, LCMS, UV-Vis, and FTIR analysis for small molecule in-process and release testing.
  • Coordinated and designed QC Labratory waste disposal program encompassing design and construction of waste containers. Developed program for proper segregation of waste reagents.
  • Routine testing of Nitrogen-Amonia testing utilizing Nessler's reagent.
  • Performed preventive maintenance and calibrated equipment to keep laboratory in compliance with GMP standards.

Medical Technologist I

Covance
11.2015 - 08.2016
  • Performed LCMS 96 well plate analysis of Cortisol, Prednisone,Free and Total Testosterone, TT/DHT, Aldosterone (Urine and Serum), and Andro/DHEA
  • Utilized LIMS system and Analyst Software
  • LCMS troubleshooting
  • Preperation of standards and mobile phase
  • Followed laboratory protocols for specimen processing, analysis, and results reporting.
  • Analyzed laboratory findings to check accuracy of results.

Sample Handling Assistant I

Covance
03.2014 - 11.2015
  • Sample Handling and inventory of all incoming and outgoing samples
  • Documentation and scheduling of samples along with delegation of workload as Bio-Registration Team Lead
  • Solely responsible for all cryogenic freezing of designated incoming samples as well as their release to labs for analysis

Radio Operator

United States Navy
12.1995 - 08.1999
  • Skills: Inventory and custody of top-secret (top secret special category) information and materials, secure and non-secure communication
  • Deployment to Persian Gulf, Ammunition and transport offload
  • Troubleshooting of all circuit and communication equipment
  • Responsible for daily morning communication breifing for Commanding Officer
  • Surface Warfare Qualification

Education

Chemistry, Bachelors Degree - Chemistry

Purdue University
West Lafayette, IN
08.2013

Skills

  • UPLC/HPLC (Waters, Thermo, Agilent, Shimadzu)
  • LCMS
  • GC (Thermo, Agilent)
  • GCMS
  • QTRAB
  • AbSciex MS
  • TOMTEC Quadra 4
  • TECAN Freedom EVO
  • SPE DRYER
  • NMR
  • UV/VIS
  • FTIR
  • Karl Fisher(Volumetric/Coulombic)
  • Computational Chemistry—Empower Software(Waters)
  • Analyst Software(AB Sciex)
  • Chromeleon (Thermo-Fisher)
  • Chemstation
  • Computer—Microsoft Office
  • Internet Browsers
  • LIMS
  • Biology—Aseptic Technique
  • Gram Stain
  • PEGylated enzymes
  • Chemistry—Aliquoting
  • Titration
  • Recrystallization
  • Distillation
  • Sample Handling
  • Process Improvement
  • Data Collection
  • Corrective Action Planning
  • Corrective Actions
  • Data Interpretation
  • Standard Operating Procedures
  • Technical Writing
  • Technical Analysis
  • Equipment Calibration
  • Microsoft Office

Bonzai Horticulture

Trimming, pruning, and training the shape of junipers is a joy I set aside for myself.  This meditative art of maintenance allows for inflection and peace.

Timeline

Quality Control Chemist III

Ambiopharm
06.2022 - Current

Quality Control Supervisor/Quality Control Chemist

Harrington Pepsi
08.2019 - 05.2022

Quality Control Chemist II/Instrumentation Coordinator

CreoSalus,Inc
11.2017 - 06.2019

Quality Control Chemist I

Sigma-Tau/Exelead Biopharma
09.2016 - 10.2017

Medical Technologist I

Covance
11.2015 - 08.2016

Sample Handling Assistant I

Covance
03.2014 - 11.2015

Radio Operator

United States Navy
12.1995 - 08.1999

Chemistry, Bachelors Degree - Chemistry

Purdue University

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