Mlana Lore
Summary
Experienced and passionate research scientist in molecular and cell biology focused on improving human health outcomes through scientific innovation.
Overview
6
6
years of professional experience
Work History
Senior Associate Scientist II
Mosaic Biosciences
03.2024 - Current
- Independently developed and executed cell-based assays including generation of stable cell lines, multi-panel flow cytometry, ELISA, and cell growth assays to evaluate protein therapeutic drug candidates.
- Took active role in departmental and client-facing meetings, engaging with all parties and accurately presenting complex scientific data.
Associate Scientist II
Mosaic Biosciences
04.2023 - 03.2024
- Designed and executed mammalian cell-based assays to characterize protein therapeutics.
- Implemented quality control measures throughout the experimentation process to ensure the integrity of study outcomes.
- Collaborated with cross-functional teams for successful completion of projects, meeting deadlines and objectives.
Research Assistant
University Of Colorado Anschutz Medical Campus
08.2021 - 03.2023
- Developed and executed all aspects of an independent research project on the regulation of nonsense-mediated RNA decay in disease states.
- Participated in lab meetings and project presentations, and contributed to the preparation of manuscripts for publication in peer-reviewed journals.
- Mentored undergraduate and rotation students
- Secured competitive external funding sources.
Cell Biology Research Intern
National Institute Of Environmental Health Sciences
05.2021 - 08.2021
- Analyzed diverse RNA sequencing data sets using bioinformatic tools to identify patient-relevant patterns in RNA splicing during induced pluripotency.
Science Tutor
Eckerd College
01.2019 - 05.2021
- Tutored undergraduate students in cell biology, genetics, general and organic chemistry, and biochemistry.
- Assisted students in developing study skills and strategies.
- Independently led genetics laboratory sections.
Biochemistry Research Assistant
Eckerd College
08.2018 - 05.2021
- Independently conducted biochemistry research in yeast and bacterial systems.
- Presented data at multiple regional and national conferences, receiving recognition of excellence in research.
- Acquired multiple nationally competitive funding sources
Neurology Research Intern
Massachusetts General Hospital
05.2019 - 08.2019
- Optimized current laboratory protocols to analyze a novel biomarker of stroke at the gene and protein level.
Toxicology Intern
Chimerix
05.2018 - 08.2018
- Prepared written summaries of extensive literature reviews on drug-induced hepatotoxicity.
- Supported toxicology staff members in data analysis and review.
Education
PhD (No Degree) - Molecular Biology
University of Colorado Anschutz Medical Campus
Aurora, CO03.2023
Bachelor of Science - Molecular Biology
Eckerd College
St. Petersburg, FL05.2021
Skills
- Aseptic technique, mammalian, yeast, insect, and bacterial cell culture
- ELISA, flow cytometry, western blot, DNA and RNA extraction and sequencing, cloning, stable cell line generation, luminescence assays, light and fluorescent microscopy, qRTPCR
- Microsoft Office, Google Suite, GraphPad Prism, R Studio (beginner), SPSS, FlowJo
Publications
- Kolakada, D... Lore, M. , et al. (IN REVIEW, Mar 2024). Peptidyl-tRNA hydrolysis rate influences the efficiency of nonsense-mediated mRNA decay.
- Kolakada, D... Lore, M. , et al. (IN REVIEW, Feb 2024). A system of reporters for comparative investigation of EJC-independent and EJC-enhanced nonsense-mediated mRNA decay. Mol. Cell.
- Lore, M ., Muñoz, O., Jagannathan, S. (May 2023). The long and short of EJC-independent nonsense-mediated RNA decay. Biochemical Society Transactions.
- Contributing writer. Colorado RNA Club Newsletter Latest (Nov 2022). Viral RNAs.
Timeline
Senior Associate Scientist II
Mosaic Biosciences
03.2024 - Current
Associate Scientist II
Mosaic Biosciences
04.2023 - 03.2024
Research Assistant
University Of Colorado Anschutz Medical Campus
08.2021 - 03.2023
Cell Biology Research Intern
National Institute Of Environmental Health Sciences
05.2021 - 08.2021
Neurology Research Intern
Massachusetts General Hospital
05.2019 - 08.2019
Science Tutor
Eckerd College
01.2019 - 05.2021
Biochemistry Research Assistant
Eckerd College
08.2018 - 05.2021
Toxicology Intern
Chimerix
05.2018 - 08.2018
PhD (No Degree) - Molecular Biology
University of Colorado Anschutz Medical Campus
Bachelor of Science - Molecular Biology
Eckerd College