Summary
Overview
Work History
Education
Skills
Timeline
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Nithyadevi Duraisamy

Edison,NJ

Summary

I am a driven and enthusiastic Nano-biomedical scientist with over 9 years of experience specializing in biomaterials, regenerative medicine, and drug delivery systems. My research focuses on developing, validating, and integrating advanced experimental and computational models, including in-vitro and in-silico platforms, to simulate therapeutic responses. I have led innovative projects in vaccine prediction for Bovine coronavirus and the design of biomaterials targeting cardiac diseases and knee osteoarthritis. With over 5 years of collaborative experience, I have pioneered novel drug delivery strategies using biopolymer-induced nanomaterials and possess 4+ years of expertise in operating and interpreting data from advanced analytical instruments such as AFM, FESEM, UV-vis, and FTIR. Currently, as a Postdoctoral Research Fellow at Long Island University, I am leveraging organ-on-chip technologies to replicate human physiological responses, enhancing drug testing and validation processes. Known for creativity, quick learning, and self-motivation, I thrive in cross-functional teams and multicultural environments. My goal is to contribute to cutting-edge advancements in healthcare by advancing personalized therapies through biomaterial synthesis, predictive modeling, and drug delivery mechanisms to improve patient outcomes.

Overview

2025
2025
years of professional experience

Work History

Postdoctoral Research Fellow

Long Island University
09.2023 - Current
  • Project Lead 1: Knee Osteoarthritis in Musculoskeletal Repair and Regeneration
    Project Establishment: Initiated and led a project targeting knee osteoarthritis through advanced tissue engineering and regenerative medicine techniques.
    Focus Areas: Concentrated on the repair and regeneration of the cartilage and menisci layers in the knee.
  • Project Lead 2: Vaccine Prediction for Bovine Coronavirus: Project Establishment: Initiated and led a project focused on predicting and developing vaccines for Bovine coronavirus.
    Vaccine Prediction Tools: Utilized advanced computational tools such as Vaxijen, ToxinPred, PSIPRED, IEDB, ImmSim, and AlphaFold2 Colab to identify potential vaccine candidates.
  • In-Silico Analysis: Conducted extensive in-silico analysis to identify epitopes and model their interactions with MHC class II molecules.
  • Project Lead 3: Precise medicine therapy for the Ventricular Desynchronization Using Virtual Twin Technology
    Project Establishment
    Developed personalized therapies for cardiac desynchronization using virtual twin simulations.

Research Assistant

Dept Of Orthopedic Surgery, UCONN Health Center
02.2019 - 12.2021

Research Experience

Research Grant Support: NIH Exploratory/Developmental Research Grant Award (R21)

  • Project Focus: Investigated electrically stimulated ionically conducting polymers as degradable biological grafts, in contrast to synthetic and non-degradable biological grafts.

Specialization Areas:

  • Ionically Conducting Biopolymers: Advanced knowledge in the development and application of biopolymers for medical use.
  • Electrical and Mechanical Stimulation: Pioneered techniques to stimulate tissue, bone, and nerve healing.
  • Targeted Drug Therapy: Developed methods for targeted drug delivery through 3D imprinting and electrospinning.
  • Technological Expertise:3D Imprinting: Leveraged 3D printing technology to create scaffolds and grafts with high precision.
  • Electrospinning: Fabricated nanoscale fibers suitable for tissue engineering applications.
  • Electrochemical Theory: Applied electrochemical principles to improve the effectiveness of biopolymers.

Assistant Professor

Dept Of Physics, Erode Builders Educational Trusts
08.2015 - 05.2016
  • Innovative Teaching Techniques: Proficient in using lectures, media, group discussions, and role-playing to create an engaging and effective learning environment.
  • Student-Centered Approach: Experienced in working with students individually and in small groups to reinforce concepts and enhance academic performance.
  • Commitment to Student Success: Dedicated to helping students achieve their academic goals through tailored support and encouragement.

Nano-analytical laboratory technologist

  • Analytical Instrumentation Proficiency:
    Atomic Force Microscopy (AFM):
    - Trained in the operation and analysis of samples using AFM.
    - Evaluated surface topography and material properties with high precision.
    Ultraviolet Spectroscopy (UV-Vis):
    - Operated UV-Vis spectroscopy to analyze sample absorbance and concentration.
    - Interpreted spectral data to determine the optical properties of materials.
    Fourier Transform Infrared Spectroscopy (FTIR):
    - Conducted FTIR analysis to identify chemical bonds and functional groups in samples.
    - Interpreted IR spectra for material characterization.
    Scanning Electron Microscopy (SEM) and Energy Dispersive X-ray Analysis (EDAX):
    - Operated SEM for high-resolution imaging of sample surfaces.
    - Performed EDAX to determine the elemental composition of samples.
    - Evaluated and interpreted SEM and EDAX data for comprehensive material analysis.

Doctoral Researcher

Bharathiar University
04.2011 - 09.2015

Title: In-vivo and In-vitro Studies on Bio-compatible Pure and Drug-loaded Biopolymer Induced Silver/Titanium Dioxide Core-shell Nanoparticles for Targeted Breast Cancer Therapy

  • Polymeric Induced Metal/Metal Oxide Platforms:Designed and developed polymeric induced metal/metal oxide platforms to investigate the pathophysiology of the bacterial pathogen Staphylococcus aureus.
    Applied these platforms for bioimaging and targeted drug delivery to breast cancer tissues.
  • Charge Manipulation with Biosurfactant Polymers:Utilized biosurfactant polymers such as polyethylene glycol (PEG) and sodium alginate to create positive and negative charges.
    Attached anticancer drugs between the metal/metal oxide nano core-shell layers for enhanced drug delivery.
  • Development of Anticancer Drug-loaded Nanoparticles:Conducted unique research on anticancer drug-loaded core-shell nanoparticles (nanospheres) using Letrozole and Doxorubicin.
    Employed the Stober chemical method for nanoparticle synthesis.
    Conducted in-vivo studies using chemically induced animal models (Xenograft studies) with SD-type rats to evaluate the efficacy and targeting capabilities of the developed nanoparticles.

Education

certification Completed course certification in “Learn Bioinformatics from scratch (Theory & Practical) -

Udemy
01-2023

Ph.D - Interdisciplinary Physics-Material Science

Bharathiar University
09.2015

PG Diploma - Nanoscience and Technology

Bharathiar University - Bharathiar University
12.2010

Master of Philosophy - Physics

Bharathiar University
10.2010

Master of Science - Physics

PSG College of Arts and Science
05.2009

Bachelor of Science - Physics

Vellalar College For Women
05.2007

Skills

Areas of Expertise

  • Chemical and Wet-Lab Techniques
  • In-silico Modeling and Analysis
  • Cell Culture and Biological Assays
  • Analytical Instrumentation
  • Scientific Software and Computational Tools
  • Teaching and Mentorship
  • Scientific Publishing and Peer Review

Independent Researcher

  • Conducted research on biological and photocatalytic nanomaterials for water purification and targeted therapeutic treatments involving redox reactions
  • Designed and executed chemical synthesis methods for Bio-nonmaterial production
  • Analyzed metal and drug release using dialysis membrane techniques
  • Conducted various in-vitro assays, including cytotoxicity, MTT assay, DNA assay, live/dead assay, protein leakage, ALP/ALZ assay
  • Performed ELISA, Western Blot, histology, and immunohistochemistry
  • Utilized advanced analytical tools such as UV-visible spectroscopy, FTIR, XRD, Raman spectroscopy, TEM, DSC, TGA, NMR, and dynamic light scattering

In-silico Protocols

  • Used Biovia Discovery Studio from Dassault systems for biomolecule interaction studies
  • Applied Pymol and AutoDock for molecular docking and visualization
  • Employed vaccine prediction tools (Vaxijen, ToxinPred, PSIPRED, IEDB tool, ImmSim, SnapGene, AlphaFold2 Colab) for computational biology research

Cell Culture Studies

  • Cultured various cell lines including HMSCs, fibroblasts, keratinocytes, Schwann cells, monocytes, and MCF-7 breast cancer cell lines
  • Managed co-culture conditions and differentiation protocols
  • Conducted paraffin embedding, sectioning, and H&E staining

Teaching and Mentorship

  • Teaching Human anatomy and Physiology for Medicine & Nursing Undergraduate students
  • Taught and mentored students in nanobiomaterial research and related fields
  • Provided guidance on experimental protocols and data analysis

Journal Reviewer

  • Reviewed scientific manuscripts for peer-reviewed journals, ensuring the quality and integrity of published research

Timeline

Postdoctoral Research Fellow

Long Island University
09.2023 - Current

Research Assistant

Dept Of Orthopedic Surgery, UCONN Health Center
02.2019 - 12.2021

Assistant Professor

Dept Of Physics, Erode Builders Educational Trusts
08.2015 - 05.2016

Doctoral Researcher

Bharathiar University
04.2011 - 09.2015

Ph.D - Interdisciplinary Physics-Material Science

Bharathiar University

PG Diploma - Nanoscience and Technology

Bharathiar University - Bharathiar University

Master of Philosophy - Physics

Bharathiar University

Master of Science - Physics

PSG College of Arts and Science

Bachelor of Science - Physics

Vellalar College For Women

Nano-analytical laboratory technologist

certification Completed course certification in “Learn Bioinformatics from scratch (Theory & Practical) -

Udemy
Nithyadevi Duraisamy