Purva Sethi
Kansas City,MO
Summary
Dynamic professional with a robust background in biomarker development, immunoassays, nanoparticle development and stem cell research. Expert in clinical trial coordination and stem cell culture techniques, complemented by strong skills in scientific communication and digital marketing. Proven track record of driving awareness and achieving regulatory compliance, showcasing a blend of technical proficiency and strategic acumen. Networked with elite research teams from Switzerland, Italy and Phoenix scientific institutions to develop and improve research protocols for biomarker development. Conducted complicated research with integrity and great attention to detail.
Overview
8
8
years of professional experience
Work History
Postdoctoral Researcher
Kansas City University, Kansas City, MO, USA
2023.03 - Current
- To understand if the accumulation of TDP-43 (platelets) is parallel to Amyotrophic Lateral Sclerosis (ALS) pathophysiology in Nervous system
- To develop and test immunoassays employing proprietary antibodies by using very efficient Capillary electrophoresis immunoassay (CEI technique)
- To evaluate the presence of antibodies in brain associated forms of TDP-43 in platelets
- Enhanced research outcomes by designing and implementing innovative experiments for blood based biomarker development.
- Improving research efficiency by suggesting the accumulation of pmTDP-43 in platelets may correlate to its pathological aggregation in neurons
- Secured grant funding for collaborative projects between industrial and academic partners. It will leverage expertise in ALS-associated biochemistry, gene regulation, cell biology and blood-based biomarker development, through persuasive proposal writing and networking efforts.
- Presented research findings at international conferences, fostering knowledge exchange among peers.
Medical Lab Assistant (MLA)
Butler Memorial Hospital
2021.09 - 2022.09
- Real time COVID specimen testing
- Enhanced patient care by maintaining accurate records of lab results and communicating with medical professionals.
- PCR standardized protocols using PANTHER and CEPHEID analyzers
- Respiratory Panel Analyses using EPlex analyzer
- Handling Meditech Expanse
- Microbiology Processing: Urine culture, wood cultures, stool cultures, Strep Screens and etc.
Chair Person (Moderator)
StemCyte Inc. USA
2020.09 - 2021.03
Moderate webinars with opinion leaders to generate awareness on various topics like:
- Fostered better understanding towards potential of stem cells and stem cell banking
- Enhanced board communication by implementing a structured meeting agenda and minutes system.
- HLA matching
- Pandemic and pregnancy planning
- New born and infant care
- Overcoming the fear of labor
Leading various training sessions on:
- Medico marketing
- Stem cell preservation techniques
Head (Marketing and Medical Affairs)
StemCyte Inc. (USA)
2018.02 - 2019.09
- Stem cell isolation and characterization from cord blood
- Clinical trial coordination
- Meeting opinion leaders
- Developing marketing strategies
- CME conduction
- Medico marketing training
Manager (Medical Affairs)
StemCyte Inc. (USA)
2018.01 - 2018.12
- Provided responses to regulatory agencies regarding product information or issues.
- Analyzed field studies and reports, compiled information and submitted concise and informative summaries.
- Worked with internal team members to accomplish regulatory goals and achieve full compliance with all products.
Transplant Coordinator
StemCyte Inc. (USA)
2016.03 - 2018.01
- Reviewed medical testing requests to determine validity of diagnostic testing requests.
- Improved patient care by providing thorough education on the transplant process and post-operative care.
- Enhanced transplant coordination by streamlining communication among multidisciplinary teams.
- Optimized patient outcomes through meticulous pre-transplant evaluations and assessments.
- Collaborated with medical staff to develop individualized care plans for each transplant candidate.
- Provided ongoing education for clinical staff on transplantation topics, promoting a knowledgeable workforce.
- Educated patients on preventive healthcare strategies and at-home care.
Education
Ph.D. - Stem Cell Nanotechnology
Narsee Monjee Institute of Management And Science
Mumbai-India2015
Master of Science - Applied Microbiology And Biotechnology (AMBT)
Banasthali Vidyapith
Jaipur-India2010
Bachelor of Science - Biotechnology (Honors)
Banasthali Vidyapith
Jaipur,India2008
Skills
- Performing Immunoassay and antibody optimization by using CEI technique
- Stem Cell culture and differentiation along with other cell culture techniques
- Nanoparticle Synthesis and Characterization
- Mammalian Cell Culture, freezing, thawing, isolation
- Blotting techniques, PCR, Toxicity Studies
- HLA Matching and Computational skills
- Clinical Trial Coordination
- Sales Training and Product Development
- Biostatistics
- Scientific writing and paper publications
- Social media and digital marketing
Voluntary Work
Shree Pacetronix Pvt.Ltd./Biopace technology -India/USA : Assisted Pacemaker Implantation in order to help the poor patients in need in India,Indore.
Choitram Charitable Hospital-India,Indore: Teaching Pathology to nurses and developing their skill for better healthcare practice.
Research Projects
PhD Project: Synthesis and Characterization of novel nanoparticles and studies on their interactions with Stem cells
This study basically focused on detailed cellular interactions of human serum albumin coated iron oxide nanoparticles (HSA-IONPs) with the umbilical cord derived human mesenchymal stem cells (hUC-MSCs). It highlights minimum membrane damage and mitochondrial impairment post internalization which was further confirmed by the lowest detection of reactive oxygen species after HSA-IONPs internalization.
further, the labeling of the isolated stem cells did not alter the cytoskeletal integrity and morphology of hUC-MSCs. The MRI analysis also proved the maintenance of contrast signal generation even after 28 days in differentiated hUC-MSCs.
HSA-IONPs proved to be promising alternative for future pre-clinical studies in comparison to the other commercially available IONPs for stem cell based therapies in labeling and tracking the transplanted cells.
Publications
- Sanganeria P, Sachar S, Chandra S, Bahadur D, Ray P & Khanna A. 2015. Cellular internalization and detailed toxicity analysis of protein immobilized iron oxide nanoparticles. J Biomed Mater Part B:Appl Biomater, 103B: 125-134. (IF=3.18)
- Sanganeria P, Sachar S, Chandra S, Bahadur D, Ray P & Khanna A. 2015. Effect of HSA coated iron oxide labeling on human umbilical cord derived mesenchymal stem cells. Nanotechnology, 26(12), 125103. (IF=3.82)
- Ashish S, Rodriguez RR, Sethi P, Yu F, Raj M. Anaplastic Lymphoma Kinase (ALK) Mutation-Targeting Treatment With Alectinib in Lung Adenocarcinoma and Primary Cutaneous Marginal Zone B-Cell Lymphoma. Cureus. 2022 Oct 4;14(10):e29922. doi: 10.7759/cureus.29922. PMID: 36348885; PMCID: PMC9633320.
Conferences and certifications
- Participated in annual Target-ALS Meeting, Boston 7th -9th May, 2024.
- Live podium presentation at KCU’s 2024 Research Symposium 2nd -5thApril, 2024.
- Participated in annual Target-ALS Meeting, Boston 5th -7th May, 2023.
- Invited as Speaker at, "World Summit on Stem Cells and Immunotechnology" organized by Shunxi Stem Cell and Regenerative Medicine, kunming, Yunnan Province, China-2017.
- Best Poster Award received at International Conference on Nanoscience and Technology (ICONSAT-2014), India
- Post graduate diploma in German Language
- Diploma in Biostatistics
Additional Information
USA Citizenship (2024)
Timeline
Postdoctoral Researcher
Kansas City University, Kansas City, MO, USA
2023.03 - Current
Medical Lab Assistant (MLA)
Butler Memorial Hospital
2021.09 - 2022.09
Chair Person (Moderator)
StemCyte Inc. USA
2020.09 - 2021.03
Head (Marketing and Medical Affairs)
StemCyte Inc. (USA)
2018.02 - 2019.09
Manager (Medical Affairs)
StemCyte Inc. (USA)
2018.01 - 2018.12
Transplant Coordinator
StemCyte Inc. (USA)
2016.03 - 2018.01
Ph.D. - Stem Cell Nanotechnology
Narsee Monjee Institute of Management And Science
Master of Science - Applied Microbiology And Biotechnology (AMBT)
Banasthali Vidyapith
Bachelor of Science - Biotechnology (Honors)
Banasthali Vidyapith
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